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Climate projections from global circulation models (GCMs), part of the Coupled Model Intercomparison Project 6 (CMIP6), are often employed to study the impact of future climate on ecosystems. However, especially at regional scales, climate projections display large biases in key forcing variables such as temperature and precipitation. These biases have been identified as a major source of uncertai

Baltic Earth is an independent research network of scientists from all Baltic Sea countries that promotes regional Earth system research. Within the framework of this network, the Baltic Earth Assessment Reports (BEARs) were produced in the period 2019-2022. These are a collection of 10 review articles summarising current knowledge on the environmental and climatic state of the Earth system in the

Land-cover changes have a clear impact on local climates via biophysical effects. European land cover has been affected by human activities for at least 6000 years, but possibly longer. It is thus highly probable that humans altered climate before the industrial revolution (AD1750–1850). In this study, climate and vegetation 6000 years (6 ka) ago is investigated using one global climate model, two

Time-domain spectroscopy encompasses a wide range of techniques, such as Fourier-transform infrared, pump-probe, Fourier-transform Raman, and two-dimensional electronic spectroscopies. These methods enable various applications, such as molecule characterization, excited state dynamics studies, or spectral classification. Typically, these techniques rarely use sampling schemes that exploit the prio

Background: The absence of Epithelial Membrane Protein 3 (EMP3) on red blood cells (RBCs) underlies the MAM-negative (MAM−) phenotype. EMP3 is a ubiquitous protein found at low levels in most tissues but with higher expression in hematopoietic cells. Low levels of CD44 are a signature of MAM− RBCs due its proposed physical interaction with EMP3, indicating that EMP3 stabilises CD44 in the membrane

Recently, many forms of audio industrial applications, such as sound monitoring and source localization, have begun exploiting smart multi-modal devices equipped with a microphone array. Regrettably, model-based methods are often difficult to employ for such devices due to their high computational complexity, as well as the difficulty of appropriately selecting the user-determined parameters. As a

In this paper, we revisit the problem of estimating the relative pose from a sparse set of point-correspondences. For each point-correspondence we also estimate the relative depth, i.e. the relative distance to the scene point in the two images. This yields an additional constraint, allowing us to use fewer matches in RANSAC to generate the pose candidates. In the paper we propose two novel minima

BACKGROUND: Previous studies have demonstrated an association between transplantation rate per center and postoperative mortality after heart transplantation. In 2011, Sweden centralized heart transplants and waiting lists, reducing the number of centers from 3 to 2. We aimed to assess the active waiting time and pre- and post-transplant mortality before and after centralization.METHODS: Heart tra

Natural killer (NK) cells represent the cytotoxic member within the innate lymphoid cell (ILC) family that are important against viral infections and cancer. Although the NK cell emergence from hematopoietic stem and progenitor cells through multiple intermediate stages and the underlying regulatory gene network has been extensively studied in mice, this process is not well characterized in humans

Many forms of small-size radars suffer from minor clock oscillations due to crystalline impurities in their internal clocks, causing time-varying clock offsets between the transmitter and the receivers. This offset causes a bias and an increased variance in the positioning of close-range targets, limiting the achievable accuracy well beyond the expected estimation limitations. This performance is

This paper develops an adaptive grid two-dimensional (2-D) direction-of-arrival (DOA) estimation technique employing an integrated dictionary framework. In contrast to using a traditional grid over distinct angles, combined angle information atoms are adopted to construct the dictionary, using a SPICE-based noise power estimate to select the active regions. To compensate for off-grid bias effects,

Uncertainty in our calculations of a system reveals the limits of our knowledge. This limitation makes model representations of the Earth system challenging and our predictions less reliable. However, despite appearing chaotic and non-linear, a system always follows a deterministic trajectory, which can often be expressed probabilistically. Building on this concept, this thesis applies data assimi

BACKGROUND: Malaria remains a significant public health concern, especially for the deadliest parasite, Plasmodium falciparum. During acute malaria, various cytokines, including osteopontin (OPN), regulate the immune response. OPN has been shown to be protective against malaria in mice. Nonetheless, its precise function and potential ability to control parasites during acute malaria in humans rema

Post-marketing reports of suspected adverse drug reactions are important for establishing the safety profile of a medicinal product. However, a high influx of reports poses a challenge for regulatory authorities as a delay in identification of previously unknown adverse drug reactions can potentially be harmful to patients. In this study, we use natural language processing (NLP) to predict whether

Global wetlands are the largest and most uncertain natural source of atmospheric methane (CH4). The FLUXNET-CH4 synthesis initiative has established a global network of flux tower infrastructure, offering valuable data products and fostering a dedicated community for the measurement and analysis of methane flux data. Existing studies using the FLUXNET-CH4 Community Product v1.0 have provided inval

Background: Long-term recovery following critical COVID-19 has not been sufficiently studied. Objective: The primary objective was to describe changes in functional outcome and Health-Related Quality of Life (HRQoL) between 3 and 12 months in critically ill COVID-19 survivors. The secondary objective was to investigate factors associated with good functional outcome and HRQoL at 12 months. Methods

This article addresses the problem of multi-target localization from acoustic time delay measurements in a 3-D underwater environment, taking into account the depth-dependent sound speed of the underwater wave propagation. Specifically, we formulate the problem as an optimal mass transport (OMT) optimization over a grid of potential candidate positions. By exploiting an iterative refinement approa

Filter exchange imaging (FEXI) is a double diffusion-encoding (DDE) sequence that is specifically sensitive to exchange between sites with different apparent diffusivities. FEXI uses a diffusion-encoding filtering block followed by a detection block at varying mixing times to map the exchange rate. Long mixing times enhance the sensitivity to exchange, but they pose challenges for imaging applicat