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BACKGROUND:: In the nineteenth century, prior to the introduction of the cuff sphygmomanometer, stiffening of arteries was recognized as an indicator of vascular ageing and cardiovascular risk. Through the twentieth century, views on vascular ageing came to focus on brachial blood pressures and on occlusive atherosclerotic disease. Such focus deflected attention from primary ageing changes, repres
Introduction. The aetiology and pathogenesis of ulcerative colitis (UC) are essentially unknown. Galectins are carbohydrate-binding lectins involved in a large number of physiological and pathophysiological processes. Little is known about the role of galectins in human UC. In this immunohistochemical exploratory study, both epithelial and inflammatory cell galectin expression were studied in pati
n this paper a new model, tailor-made for nutrient deficient aerobic COD removal, is presented. The Activated Sludge Model No. 1 is chosen as a basis for model development. The original model is extended to include (1) phosphorus state variables; (2) phosphorus and nitrogen limited heterotrophic growth; (3) additional 'luxury' uptake of phosphorus and (4) a separate active biomass component to mod
The far-field spatial distributions of high-order harmonics in an ionized medium have been investigated using a computer model that includes both the single atom effects and the collective effects of the medium. The results show that depletion of the non-linear medium due to ionization and radial phase variations across the gas jet cause broadening and complicated structures in the far-field spati
To cite this article: Stalder J-F, Barbarot S, Wollenberg A, Holm EA, De Raeve L, Seidenari S, Oranje A, Deleuran M, Cambazard F, Svensson A, Simon D, Benfeldt E, Reunala T, Mazereeuv J, Boralevi F, Kunz B, Misery L, Mortz CG, Darsow U, Gelmetti C, Diepgen T, Ring J, Moehrenschlager M, Gieler U, Taïeb A, for the PO-SCORAD Investigators Group. Patient-Oriented SCORAD (PO-SCORAD): a new self-assessm
An interpretation is given of the threshold photoelectron spectrum of Ar between the P-3 and D-1 double-ionization thresholds. In this region the observed spectrum is less cluttered than below the P-3 thresholds and the interpretation is more straightforward. One of the characteristic features of the spectrum is the excitation to Rydberg orbitals with high angular momentum l in agreement with the
Autoantibodies to GAD65 (GAD65Ab) are prominent in type 1 diabetes. These autoantibodies may be present both years before and after the clinical diagnosis of type 1 diabetes and are widely used as a marker for the disease. Recently it has been demonstrated that progression to type 1 diabetes is accompanied by GAD65Ab epitope maturation. Here we examine whether autoantibody maturation processes als
The authors sought to non-invasively defect changes in atrial fibrillation rhythm during autonomic provocative maneuvers. Digital Holter from 23 patients with chronic AF before and after active postural change were subjected to routine editing, and then underwent QRS and T wave subtraction, leaving pure atrial fibrillatory records. Spectral analysis by autoregressive method was performed on this r
An in-house written software package was used to generate templates of QRS complexes and T waves using self-similarity techniques, and leave a residual signal representing only atrial activity. The templating performance differences between individual ECG leads were tested. The mean number of templates in each of the 3 ECG leads was 8±4, 2±1, 7±5 for the QRS complexes, and 11±5, 11±8, 10±5 for the
Resistivity imaging in combination with drill hole information is a powerful tool in geotechnical site investigations. Traditionally the resistivity data is inverted with a 2D smooth inversion algorithm, resulting in a minimum structure model. In the geological interpretation it can be difficult to determine sharp layer boundaries in these models. An additional parameterized inversion of resistivi
Models of community organization involve variations of the top-down (predator control) or bottom-up (nutrient limitation) hypotheses. Verbal models, however, can be interpreted in different ways leading to confusion. Therefore, we predict from first principles the range of possible trophic level interactions, and define mathematically the instantaneous effects of experimental perturbations. Some o
Cytomegalovirus (CMV) has been implicated in the pathogenesis of atherosclerosis. Abdominal aortic aneurysm is regarded traditionally as a consequence of atherosclerosis. Several microorganisms have been suggested as possible contributing factors for the development of abdominal aortic aneurysm. The relevance of CMV in the processes underlying the development, expansion, and rupture of abdominal a
The main aim of the present study was to investigate whether or not temperament dimensions are stable over time. Twenty-six patients (21 women and five men) filled in the Karolinska Scales of Personality (KSP) both at admission after a suicide attempt (index) and at follow-up 5 years later. KSP changes were significantly associated with low severity of psychiatric symptoms and no reported reattemp
