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Background:Computed tomographic angiography (CTA) may require a non-contrast enhanced dataset for the diagnostic workup. By using dual-energy acquisition, it is possible to obtain a virtual non-contrast-enhanced (VNC) dataset, thereby possibly eliminating the non-contrast acquisition and reducing the radiation dose.Purpose:To compare image quality of VNC images reconstructed from arterial phase du
Deep learning has the potential to drastically increase the accuracy and efficiency of prostate cancer diagnosis, which would be of uttermost use. Today the diagnosis is determined manually from H&E stained specimens using a light microscope. In this paper several different approaches based on convolutional neural networks for prostate cancer classification are presented and compared, using th
Transition-metal complexes are used as photosensitizers1, in light-emitting diodes, for biosensing and in photocatalysis2. A key feature in these applications is excitation from the ground state to a charge-transfer state3,4; the long charge-transfer-state lifetimes typical for complexes of ruthenium5 and other precious metals are often essential to ensure high performance. There is much interest
We created a system to simulate the heart allocation process in a transplant queue, using a discrete event model and a neural network algorithm, which we named the Lund Deep Learning Transplant Algorithm (LuDeLTA). LuDeLTA is utilized to predict the survival of the patients both in the queue and after transplant. We tried four different allocation policies: wait time, clinical rules and allocating
In this study, the processes behind observed new particle formation (NPF) events and subsequent organic-dominated particle growth at the Pallas Atmosphere-Ecosystem Supersite in Northern Finland are explored with the one-dimensional column trajectory model ADCHEM. The modeled sub-micron particle mass is up to ∼75 % composed of SOA formed from highly oxidized multifunctional organic molecules (HOMs
Heart transplantations have made it possible to extend the median survival time to 12 years for patients with end-stage heart diseases. This operation is unfortunately limited by the availability of donor organs and patients have to wait on average about 200 days in a waiting list before being operated. This waiting time varies considerably across the patients. In this paper, we studied the outcom
This study investigated the feasibility of targeting the free, unbound forms of prostate-specific antigen (fPSA) for in vivo imaging of prostate adenocarcinomas (PCa), as PSA is produced and secreted at abundance during every clinical stage and grade of PCa, including castration-resistant disease. We injected (125)I-labeled monoclonal antibody PSA30 (specific for an epitope uniquely accessible on
The search for new cancer biomarkers is essential for fundamental research, diagnostics, as well as for patient treatment and monitoring. Whereas most cancer biomarkers are biomolecules, an increasing number of studies show that mechanical cues are promising biomarker candidates. Although cell deformability has been shown to be a possible cancer biomarker, cellular forces as cancer biomarkers have
There is significant interest from the medical andneuroscience communities for studying the behavior of zebrafishlarvae, particularly in the context of drug testing. In this paper, wepropose a method for analyzing the behavior of zebrafish larvaein a high-throughput system using automatic image analysis.Specifically, algorithms for estimating the poses of the larvae invideo recordings are presente
Simultaneous sound event localization and detection (SELD) for multi-source sound events is an open research field. The Multi-ACCDOA format is a popular way to handle activity-coupled sound events where the same class occurs at multiple locations at the same time. An important part is the Auxiliary Duplicating Permutation Invariant Training (ADPIT) paradigm that calculates the loss for order-agnos
Nonvolatile memory devices based on ferroelectric HfxZr1-xO2 (HZO) show great promise for back-end integrable storage and for neuromorphic accelerators, but their adoption is held back by the inability to scale down the HZO thickness without violating the strict thermal restrictions of the Si CMOS back end of line. In this work, we overcome this challenge and demonstrate the use of nanosecond puls
Effectively identifying deviations in real-world medical time-series data is a critical endeavor, essential for early surveillance of disease outbreaks. This paper demonstrates the integration of time-series anomaly detection techniques to develop surveillance systems for disease outbreaks. Utilizing data from Sweden's telephone counseling service (1177), we first illustrate the trends in physical
Importance: The lack of an in vivo measure for α-synuclein (α-syn) pathology until recently has limited thorough characterization of its brain atrophy pattern, especially during early disease stages. Objective: To assess the association of state-of-the-art cerebrospinal fluid (CSF) seed amplification assays (SAA) α-syn positivity (SAA α-syn+) with magnetic resonance imaging (MRI) structural measur
Understanding the mechanisms governing interfacial charge transfer in photoactive layer is crucial for optimizing photogenerated charge separation efficiency. In this study, the interfacial charge transfer process is regulated by applying external electric field (Fext) and ternary hydrogen bonding strategies. We observe significant changes in the excited state properties and charge transfer parame
In organic solar cells (OSCs), comprehending the charge transfer mechanism at D/A interfaces is crucial for photoinduced charge generation and enhancing power conversion efficiency (PCE). The charge transfer mechanism and photovoltaic performance of the parallel stacking interface configuration of the PTQ10 polymer donor and T2EH non-fullerene acceptor (NFA) are systematically studied at the micro
The handover (HO) procedure is one of the most critical functions in a cellular network driven by measurements of the user channel of the serving and neighboring cells. The success rate of the entire HO procedure is significantly affected by the preparation stage. As massive Multiple-Input Multiple-Output (MIMO) systems with large antenna arrays allow resolving finer details of channel behavior, w
