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BACKGROUND: It is widely believed that cancer can be prevented by high intake of fruits and vegetables. However, inconsistent results from many studies have not been able to conclusively establish an inverse association between fruit and vegetable intake and overall cancer risk. METHODS: We conducted a prospective analysis of the European Prospective Investigation into Cancer and Nutrition (EPIC)

A summary of the aging and material validation studies carried out for the ATLAS Transition Radiation Tracker (TRT) is presented. Particular emphasis is put on the different phenomena observed in straw tubes operating with the chosen Xe/CF4/CO2 mixture. The most serious effects observed are silicon deposition on the anode wire and damage of the anode wire gold plating. Etching phenomena and active

Wild and managed bees are well documented as effective pollinators of global crops of economic importance. However, the contributions by pollinators other than bees have been little explored despite their potential to contribute to crop production and stability in the face of environmental change. Non-bee pollinators include flies, beetles, moths, butterflies, wasps, ants, birds, and bats, among o

The Bronze Age of Eurasia (around 3000-1000 BC) was a period of major cultural changes. However, there is debate about whether these changes resulted from the circulation of ideas or from human migrations, potentially also facilitating the spread of languages and certain phenotypic traits. We investigated this by using new, improved methods to sequence low-coverage genomes from 101 ancient humans

Genome-wide association studies have identified >50 common variants associated with kidney function, but these variants do not fully explain the variation in eGFR. We performed a two-stage meta-analysis of associations between genotypes from the Illumina exome array and eGFR on the basis of serum creatinine (eGFRcrea) among participants of European ancestry from the CKDGen Consortium (nStage1: 111

Precision medicine aims to predict a patient's disease risk and best therapeutic options by using that individual's genetic sequencing data. The Critical Assessment of Genome Interpretation (CAGI) is a community experiment consisting of genotype-phenotype prediction challenges; participants build models, undergo assessment, and share key findings. For CAGI 4, three challenges involved using exome-

High-risk human papillomavirus (HPV) types cause most cervical carcinomas and are sexually transmitted. Sexual behavior therefore affects HPV exposure and its cancer sequelae. The International Collaboration of Epidemiological Studies of Cervical Cancer has combined data on lifetime number of sexual partners and age at first sexual intercourse from 21 studies, or groups of studies, including 10,77

Insulin resistance is a key mediator of obesity-related cardiometabolic disease, yet the mechanisms underlying this link remain obscure. Using an integrative genomic approach, we identify 53 genomic regions associated with insulin resistance phenotypes (higher fasting insulin levels adjusted for BMI, lower HDL cholesterol levels and higher triglyceride levels) and provide evidence that their link

Dementia is a global problem and major target for health care providers. Although up to 45% of cases are primarily or partly due to cerebrovascular disease, little is known of these mechanisms or treatments because most dementia research still focuses on pure Alzheimer's disease. An improved understanding of the vascular contributions to neurodegeneration and dementia, particularly by small vessel

Multiple myeloma (MM) is a plasma cell malignancy with a significant heritable basis. Genome-wide association studies have transformed our understanding of MM predisposition, but individual studies have had limited power to discover risk loci. Here we perform a meta-analysis of these GWAS, add a new GWAS and perform replication analyses resulting in 9,866 cases and 239,188 controls. We confirm all

A recent comprehensive whole genome analysis of a large breast cancer cohort was used to link known and novel drivers and substitution signatures to the transcriptome of 266 cases. Here, we validate that subtype-specific aberrations show concordant expression changes for, for example, TP53, PIK3CA, PTEN, CCND1 and CDH1. We find that CCND3 expression levels do not correlate with amplification, whil

Background: Long-term exposure to air pollution has been hypothesized to elevate arterial blood pressure (BP). The existing evidence is scarce and country specific. Objectives: We investigated the cross-sectional association of long-term traffic-related air pollution with BP and prevalent hypertension in European populations. Methods: We analyzed 15 population-based cohorts, participating in the E

BACKGROUND: Previously, small studies have found that BRCA1 and BRCA2 breast tumors differ in their pathology. Analysis of larger datasets of mutation carriers should allow further tumor characterization.METHODS: We used data from 4,325 BRCA1 and 2,568 BRCA2 mutation carriers to analyze the pathology of invasive breast, ovarian, and contralateral breast cancers.RESULTS: There was strong evidence t

Whilst common genetic variation in many non-coding genomic regulatory regions are known to impart risk of colorectal cancer (CRC), much of the heritability of CRC remains unexplained. To examine the role of recurrent coding sequence variation in CRC aetiology, we genotyped 12,638 CRCs cases and 29,045 controls from six European populations. Single-variant analysis identified a coding variant (rs31

Squamous cell carcinomas (SqCC) of the aerodigestive tract have similar etiological risk factors. Although genetic risk variants for individual cancers have been identified, an agnostic, genome-wide search for shared genetic susceptibility has not been performed. To identify novel and pleotropic SqCC risk variants, we performed a meta-analysis of GWAS data on lung SqCC (LuSqCC), oro/pharyngeal SqC

Hur vi skriver kan avslöja lögner – ny forskning kan bli verktyg för rättsväsendet Hur vi skriver kan avslöja lögner – ny forskning kan bli verktyg för rättsväsendet Av Gisela Lindberg - Publicerad den 11 februari 2026 Foto: Mostphotos För att få en uppfattning om någon ljuger studerar man ofta hur personen talar. Ny forskning tyder på att det kan vara lovande att också undersöka hur någon skriver

https://www.ht.lu.se/article/hur-vi-skriver-kan-avsloeja-loegner-ny-forskning-kan-bli-verktyg-foer-raettsvaesendet - 2026-04-20

Från forskning till rättvisa: Sanningskommissionen för det samiska folket i fokus | Department of History 23 Apr Från forskning till rättvisa: Sanningskommissionen för det samiska folket i fokus 23 April 2026 13:15 to 15:30 Seminar Panelsamtal utifrån forskningsantologin "Marken, vattnet, tankarna - Konsekvenser för samer av svensk politik" framtagen av Sanningskommissionen för det samiska folket

https://www.historiska.lu.se/en/about-the-department/calendar/event/fran-forskning-till-rattvisa-sanningskommissionen-det-samiska-folket-i-fokus/ - 2026-04-23

Från forskning till rättvisa: Sanningskommissionen för det samiska folket i fokus | Humanistiska och teologiska fakulteterna 23 apr Från forskning till rättvisa: Sanningskommissionen för det samiska folket i fokus 23 april 2026 13:15 till 15:30 Seminarium Panelsamtal utifrån forskningsantologin "Marken, vattnet, tankarna - Konsekvenser för samer av svensk politik" framtagen av Sanningskommissionen

https://www.ht.lu.se/om-fakulteterna/aktuellt/kalendarium/evenemang/fran-forskning-till-rattvisa-sanningskommissionen-det-samiska-folket-i-fokus/ - 2026-04-23

Från forskning till rättvisa: Sanningskommissionen för det samiska folket i fokus | Mänskliga rättigheter 23 apr Från forskning till rättvisa: Sanningskommissionen för det samiska folket i fokus 23 april 2026 13:15 till 15:30 Seminarium Panelsamtal utifrån forskningsantologin "Marken, vattnet, tankarna - Konsekvenser för samer av svensk politik" framtagen av Sanningskommissionen för det samiska fo

https://www.mrs.lu.se/om-oss/kalendarium/evenemang/fran-forskning-till-rattvisa-sanningskommissionen-det-samiska-folket-i-fokus/ - 2026-04-23

Från forskning till rättvisa: Sanningskommissionen för det samiska folket i fokus | Historiska institutionen 23 apr Från forskning till rättvisa: Sanningskommissionen för det samiska folket i fokus 23 april 2026 13:15 till 15:30 Seminarium Panelsamtal utifrån forskningsantologin "Marken, vattnet, tankarna - Konsekvenser för samer av svensk politik" framtagen av Sanningskommissionen för det samiska

https://www.historiska.lu.se/om-institutionen/kalendarium/evenemang/fran-forskning-till-rattvisa-sanningskommissionen-det-samiska-folket-i-fokus/ - 2026-04-23