Filtyp
We performed a multistage genome-wide association study of melanoma. In a discovery cohort of 1804 melanoma cases and 1026 controls, we identified loci at chromosomes 15q13.1 (HERC2/OCA2 region) and 16q24.3 (MC1R) regions that reached genome-wide significance within this study and also found strong evidence for genetic effects on susceptibility to melanoma from markers on chromosome 9p21.3 in the
Specific alterations (mutations, deletions, insertions) of virus genomes are crucial for the functional characterization of their regulatory elements and their expression products, as well as a prerequisite for the creation of attenuated viruses that could serve as vaccine candidates. Virus genome tailoring can be performed either by using traditionally cloned genomes as starting materials, follow
Mitotic index is an important component of histologic grade and has an etiologic role in breast tumorigenesis. Several small candidate gene studies have reported associations between variation in mitotic genes and breast cancer risk. We measured associations between 2,156 single nucleotide polymorphisms (SNPs) from 194 mitotic genes and breast cancer risk, overall and by histologic grade, in the B
Introduction. The European Multiple System Atrophy-Study Group (EMSA-SG) is an academic network comprising 23 centers across Europe and Israel that has constituted itself already in January 1999. This international forum of established experts under the guidance of the University Hospital of Innsbruck as coordinating center is supported by the 5th framework program of the European Union since Marc
The techniques to measure the position of sense wires and field wires, the gas gain and the gas flow rate inside wire chambers using a collimated and filtered X-ray beam are reported. Specific examples are given using barrel modules of the Transition Radiation Tracker of the ATLAS experiment. (C) 2003 Elsevier B.V. All rights reserved.
BACKGROUND: Polymorphisms of the vitamin D receptor (VDR) gene have been implicated in the genetic regulation of bone mineral density (BMD). However, the clinical impact of these variants remains unclear.OBJECTIVE: To evaluate the relation between VDR polymorphisms, BMD, and fractures.DESIGN: Prospective multicenter large-scale association study.SETTING: The Genetic Markers for Osteoporosis consor
Popular Abstract in English Technological devices in our society are used on a daily basis. The speed in processing jobs and the memory capacity are two key parameters used to set their prices. The information is encoded with a binary system physically implemented on semiconductor circuits, where the bit 1 corresponds to a finite voltage and the bit 0 to zero voltage. In order to increase the spThis thesis aims to contribute to the field of time controlled charge and energy transport in mesoscopic systems. In Chapter 1, Chapter 2 and Chapter 3 a short review of the scattering matrix theory is presented, including both charge and energy transport, useful to understand the mathematical landscape used in Papers I, II, III and IV. Chapter 3 briefly presents the thermoelectric properties of m
Popular Abstract in Swedish Internet har under de senaste tio åren växt från marginalföreteelse till ett populärt och mycket använt medium. Många företeelser och tjänster tar steget över till Internet och bland dessa finns även journalistik. I fokus för denna avhandling står förändringsprocesser för journalistikens villkor, ideal och normer när nyhetsjournalistiken bedrivs på?Internet studerade utDuring the last decade the Internet has become a widely used source of information for the average person and also a publishing tool for media corporations. The transition of journalism from one medium to another is one with important implications as the world wide public consumption of online news grows. This dissertation puts focus on how journalistic content changes when it's published on the W
Popular Abstract in Swedish VADÅ CYTOTOXISKA OCH PROINFLAMMATORISKA EGENSKAPER HOS EOSINOFILA? Vårt immunförsvar är nödvändigt för vår överlevnad, men des's komplexitet gör det svårt att greppa. Man brukar dela upp det i ett ospecifikt och ett specifikt försvar. T och B celler ingår i det ospecifika och vita blodkroppar i det specifika. En andra uppdelning är första försvarslinjen (den barriär soEosinophils are multi-functional leukocytes involved in the pathophysiology of inflammatory diseases such as asthma and inflammatory bowel disease. Participation in some neoplastic diseases and in the host defense against helminths has also been postulated. They are considered both good and bad, protecting or harming the host. The exact roles of eosinophils and their mechanisms of action are poorl
In this special session we wish to critique and reimagine the anthropocentric present. In contemporary consumerist society (Schmitt et al., 2022), the global “free market” is presented as the solution to the environmental and climate urgency through pillars like unlimited growth, responsibilized consumers, and not least, the domination of Nature (e.g. Hornborg 2019). There are alternatives, but th
The digitalization of learning environments during the last decades has changed education at its core. At the same time as computers in the classroom offer multiple advantages, they also allow for multitasking and off-task behavior, undermining students’ attention and affecting their knowledge gains. In today’s highly digitalized classrooms, the challenge of maintaining student focus amidst pervasDue to an increase in unverified information that reaches people, data literacy, i.e. the understanding of how to interact with, and interpret information, becomes increasingly important for informed citizenship and responsible decision-making in a democratic society. Central to data literacy is the ability to draw conclusions based on existing data, as well as to interpret and evaluate numerical
Coronavirus disease 2019 (COVID-19) was first diagnosed in Scotland on 1 March 2020. During the first month of the outbreak, 2,641 cases of COVID-19 led to 1,832 hospital admissions, 207 intensive care admissions and 126 deaths. We aimed to identify the source and number of introductions of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into Scotland using a combined phylogenetic and
BACKGROUND: Nearly a quarter of patients with locally advanced (T4 stage) or perforated colon cancer are at risk of developing peritoneal metastases, often without curative treatment options. We aimed to determine the efficacy of adjuvant hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with locally advanced colon cancer.METHODS: This multicentre, open-label trial was done in nine hos
BACKGROUND: Aortic-root dissection is the leading cause of death in Marfan's syndrome. Studies suggest that with regard to slowing aortic-root enlargement, losartan may be more effective than beta-blockers, the current standard therapy in most centers.METHODS: We conducted a randomized trial comparing losartan with atenolol in children and young adults with Marfan's syndrome. The primary outcome w
Microsoft Word - ITAC01_littlista_HT20.docx Språk- och litteraturcentrum Italienska Litteraturlista ITAB19, Den gudomliga komedin, 7,5 högskolepoäng Fastställd 2022-02-10 av Styrelsen för Sektion 3 för att gälla från VT22. Obligatorisk kurslitteratur Fullständig utgåva av Dante Alighieris gudomliga komedi på svenska, engelska eller italienska, t.ex. Den gudomliga komedin, i tolkning av Ingvar Björ
https://www.sol.lu.se/media/utbildning/dokument/kurser/ITAB19/20261/ITAB19.pdf - 2026-09-14
