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Marine-derived nutritional and bioactive compounds : Proteins and amino acids

Marine ecosystems are consisted with variety of life, accounting for over 80% of the Earth's biodiversity. This rich biodiversity in marine environment includes more than 30,000 species of fish. Additionally, marine biological resources are reservoirs of numerous bioactive compounds with various physiological functions such as antioxidant, anti-inflammatory, anticancer, antiaging, antibacterial, a

Subventricular Zone-on-a-Chip : A Model to Study Neurogenesis Disruption in Neonatal Intraventricular Hemorrhage

Intraventricular hemorrhage (IVH) in preterm infants disrupts neurogenesis in the subventricular zone (SVZ), a key neurogenic niche, yet no effective treatments exist. This work develops a human SVZ-on-a-chip model to investigate the inflammatory response in IVH and its impact on neurogenesis. Using this platform, this work examines the effects of red blood cell lysate (RBCL) and hemorrhagic cereb

Long-term neurodevelopmental outcomes in extremely preterm infants born at 22–26 weeks gestation : a follow-up of 2–2.5 years across two Swedish national cohorts from 2004–2007 to 2014–2016

Objective To compare neurodevelopmental outcomes in extremely preterm (EPT) children born across two epochs in Sweden. Design and setting Nationwide population-based cohorts of infants born at 22–26 weeks’ gestation in 2004–2007 (Cohort 1) and 2014–2016 (Cohort 2), comprising 1606 live births. Survivors were assessed at 2–2.5 years’ corrected age using the same protocol design. Main outcome The pr