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Objectives: To examine the risk of progression and time to progression from penile intraepithelial neoplasia (PeIN) to invasive penile cancer in patients treated for PeIN with either surgery, laser ablation or topical treatment, and to examine recurrence risk after treatment of PeIN. Patients and Methods: Data on patients diagnosed with PeIN (n = 1122) between 2000 and 2020 were extracted from the
Objective: Screening for abdominal aortic aneurysm (AAA) defined as an infrarenal aortic diameter (IAD) of ≥30 mm reduces mortality, but managing patients with diameters of 25 to 29 mm is debated. Incorporating body surface area into the diagnostic criteria may improve the identification of those at risk of developing treatment-requiring aneurysms in this group. In a previous study, we defined a r
OBJECTIVES: To investigate the optimal duration of venoarterial extracorporeal membrane oxygenation (ECMO) for cardiogenic shock refractory to medical therapies after cardiac surgery and whether its prolonged use is justified. DATA SOURCES: Previously published articles on postcardiotomy venoarterial ECMO. STUDY SELECTION: Articles reporting on the early outcome after postcardiotomy venoarterial E
Background: The purpose of this analysis was to revisit the open US Food and Drug Administration (FDA) inspection list results from clinical trials and show the possibilities of evaluating inspection results between different world regions and explore what aspects of clinical trial deficiencies are most often reported.Aims: The aim of this study was to evaluate inspection results from different re
The dynamics of chemical reactions in solution are of paramount importance in fields ranging from biology to materials science. Because the hydrogen-bond network and proton dynamics govern the behavior of aqueous solutions, they have been the subject of numerous studies over the years. Here, we report the observation of a previously unknown associative state in the hydroxide ion that forms when a
Objective: To assess foetal circulating free foetal haemoglobin (fHbF) levels and heme defences, correlated to foetal circulatory biometry and foetal sex in severe early-onset foetal growth restriction (FGR). Design, Setting and Population: A prospective study severe early-onset foetal growth restriction pregnancies with close clinical management (estimated foetal weight (EFW) < 3rd centile and <
Background: Composite outcome measures aim to provide a more holistic view when determining the effectiveness and safety of surgical interventions. Recently, 'Ideal Outcome' (IO) harmonized the European and American composite outcome of pancreatic surgery. The rate of IO after pancreatoduodenectomy was 54% but is unknown after left pancreatectomy(LP). Methods: This transatlantic analysis included
Taking advantage of the relatively automatic and easy operation procedure, continuous-flow catalysis has become a promising wastewater treatment technique for organic dye removal. However, developing suitable packing catalysts with favorable activity and low flow resistance remains a challenging task for the construction of continuous-flow catalytic systems. In this paper, we report the preparatio
Two cast Mg–Al–Ba–Ca alloys, DieMag633 and DieMag844, are the focus of this study. Their microstructureMicrostructure consists of a eutectic Ca-rich structure, the lamellar Al2Ca, and of a hard, compact and brittle interdendritic Ba-rich phase, the Mg21Al3Ba2 phase. Both phases have a much higher hardness than the α-Mg matrix and strongly influence the crack propagationCrack propagation under quas
Recension av Mårten Ericson & Petter Lönegård, Den europeiska komedien: Antropomorfa kartor 1850–1950.
Recension av Elias Lidén (red.), Sven Hedin och hans tid.
Low-dimensional topological states have transformed our understanding of charge transportation through quantum materials. Many relevant observations have been connected to bismuth (Bi) containing materials or ultrathin Bi films. Here, we studied sub-monolayer amounts of Bi deposition on the In-terminated InSb(111)A surface using various complementary surface science techniques. Bi deposition at el
Three new genera in the lichen family Teloschistaceae, i.e.: Josefhafellia for the former Caloplaca bellemerei group, Bagliettoella for the former Gyalolechia marmorata branch and Tsarenkoella for the former Caloplaca obscurella group are described and compared with closely related genera. The positions of the species Lacrima apostatica (basionym: Loekoesia apostatica) and Neoplaca sideritis (basi
The distribution of betony (Betonica officinalis L.) is mapped using 390 herbarium specimens from 31 countries (28 European, 2 African and 1 Asian), representing ca 200 localities. Populations from 19 of these localities were used in seed cultivation experiments. Characters that correlate with their biogeography were searched for both in the herbarium material and in the cultivated material. Three
Extracellular vesicles (EVs) have been identified as important mediators of cancer metastasis, especially in the establishment of organ-specific metastatic niches. These membranous vesicles secreted by tumor cells release diverse bioactive cargo, including proteins, nucleic acids, and lipids, thereby allowing for intercellular communication and microenvironment modulation. Recent evidence demonstr
