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What do muffins and space travel have in common? Answer: They affect our genes through altered DNA methylation patterns. Two researchers who studied this recently met at the public defence of a doctoral thesis at Lund University. Andrew Feinberg from Johns Hopkins University's School of Medicine in Baltimore, USA, has often been called the "father of epigenetics”.  When the US Space Agency NASA de

https://www.ludc.lu.se/article/big-data-muffins-and-space-travel - 2025-10-17

Eric Lander, a long time collaborator of the diabetes researchers at LUDC, has been appointed as scientific advisor to Barack Obama, the new president of the United States. Eric Lander is an honorary doctor at the faculty of medicine at Lund University and member of the Scientific Advisory Board of LUDC. - It’s an honor, of course, but it's more the responsibility to serve right now, Eric Lander c

https://www.ludc.lu.se/article/ludc-and-president-obama-have-same-scientific-advisor - 2025-10-17

350 international top scientists are gathering in Malmö to attend the 10th international congress of the Immunology of Diabetes Society (IDS). The focus of the congress will be on how to prevent and cure type 1 diabetes. -Malmö hosting such an event underlines Lund University Diabetes Centre’s (LUDC) position at the absolute scientific front. Not least when it comes to clinical studies aiming to p

https://www.ludc.lu.se/article/international-scientific-congress-type-1-diabetes - 2025-10-17

In competition with about ten other European consortia, Lund University and collaborators have received a research grant of approximately 150 million SEK. The money, which is given by the European Union, will be complemented by funding from the pharmaceutical industry. The funding will be used to advance in the battle against complications caused by diabetic diseases. In addition to Lund Universit

https://www.ludc.lu.se/article/unified-european-effort-fight-diabetic-complicati - 2025-10-17

A common variant of the melatonin receptor gene increases the risk of developing type 2 diabetes. This discovery was made by two research groups at Lund University Diabetes Centre (LUDC), and reveals a completely new mechanism underlying diabetes. The finding, presented in the latest issue of the scientific journal Nature Genetics, also opens a new avenue for treating the disease. Finding that Mel

https://www.ludc.lu.se/article/unexpected-link-between-diabetes-and-sleep-hormone-melatonin - 2025-10-17

Heart attack and stroke afflicts many in spite of them having few or no known risk factors such as high blood pressure, diabetes, changes in blood fat or smoking. -Because of this it is important to be able to identify those at risk who would benefit from preventive treatment, says Olle Melander, docent at Lund University and chief physician at Akutcentrum, UMAS. He is the main author of a new art

https://www.ludc.lu.se/article/new-risk-markers-discovered-cardiac-infarction-and-stroke - 2025-10-17

The risk of becoming obese is 2.5 times higher for those who have double copies of the best known risk gene for overweight and obesity. However, this is only true if the fat consumption is high. A low fat diet neutralizes the harmful effects of the gene. “This means that the critical factor is what you eat. At least in the case of the FTO gene, the most important obesity gene identified so far” sa

https://www.ludc.lu.se/article/food-habits-are-more-important-most-important-obesity-risk-gene - 2025-10-17

Type 2 diabetes is often not caused by a lack of insulin per se, but an inability of the beta cells to secrete adequate amounts of it. Recently, scientists at LUDC have identified a previously unknown agent that plays an important role in the release of insulin. Knock-out mice that lack the ClC3 protein have a severely diminished capacity to secrete insulin in spite of intact beta cells. This find

https://www.ludc.lu.se/article/happy-insulin-cell-needs-be-sour - 2025-10-17

Children participating in the DiPiS and TEDDY studies, who are at high risk of developing type 1 diabetes, have the possibility to receive GAD vaccine. The hope is that this will stop the process and prevent the children from falling ill. Some of the children who have an increased risk of type 1 diabetes start producing antibodies directed at the insulin producing cells. This is a warning that the

https://www.ludc.lu.se/article/vaccine-offered-children-i-skania-sweden-high-risk-diabetes - 2025-10-17

The finding of a new genetic risk variant and the description of the exact underlying mechanism explains, on a molecular level, the connection between stress and diabetes. This scientific breakthrough is published online today in the journal Science. Carriers of the risk variant have stressed insulin producing cells which greatly reduces their ability to secrete insulin. Further, making the findin

https://www.ludc.lu.se/article/risk-gene-activates-stress-system-and-increases-risk-diabetes - 2025-10-17

Hyperglycemia starts a complex chain of events that damages blood vessels and cause cardiovascular disease. Scientists at Lund University Diabetes Centre (LUDC) have now been able to demonstrate why this happens, as well as how the destructive chain can be broken. This discovery represents a crucial step towards an efficient treatment of the vascular injuries that will be the cause of death for mo

https://www.ludc.lu.se/article/new-mechanism-underlying-cardiovascular-disease - 2025-10-17

Leif Groop, professor in diabetes and endocrinology at the Department of Clinical Sciences in Malmö, Lund University, has been elected to recipient of Hilda och Alfred Erikssons prize of year 2010. Leif Groop receives the prize "for pioneering research about Type 2 Diabetes" whcih is the motivation by the Academy of Science.- An honorable acknowledgement  and it is always nice to be appreciated fo

https://www.ludc.lu.se/article/royal-academy-science-praise-diabetes-professor - 2025-10-17

A recently discovered estrogen receptor in the insulin-producing cells may facilitate targeted diabetes treatment for women. The type 2 diabetes drugs that are currently available on the market have often only been tested on men. The identification of this new receptor may also explain why type 2 diabetes is less common in women than in men. "Estrogen is thought to have an important anti-diabetic

https://www.ludc.lu.se/article/female-hormone-protects-against-diabetes - 2025-10-17

Children of immigrants from countries with low risk of type 1 diabetes develop the disease more often than expected if they grow up in Sweden, which is a high-risk country. Scientists mean that it is something in the Swedish environment that causes this elevated risk. Ahmed Delli, who is a scientist at Lund University Diabetes Centre, has mapped what happens when a child moves from an area with lo

https://www.ludc.lu.se/article/moving-sweden-increases-risk-diabetes - 2025-10-17

Anders Rosengren, physician at Skåne University Hospital and researcher at Lund University Research Centre in Malmö, has received six and a half million swedish crowns from the Novo Nordisk Foundation Project of Excellence. - This means a lot. I can start a research group of my own and drive the research work faster, says Anders Rosengren.The project he presented and, in tough competition with oth

https://www.ludc.lu.se/article/large-research-grant-mapping-linkage-between-stress-and-diabetes - 2025-10-17

At the time of the atmospheric nuclear weapons testing in the 1950s and 1960s, the level of carbon-14 in the atmosphere increased dramatically. Now researchers from Lund University have developed a method for measuring the carbon-14 content in atherosclerotic plaques in patients. The measurements reveal how old and dangerous the plaques really are. "On the one hand it’s important to find out wheth

https://www.ludc.lu.se/article/nuclear-weapons-tests-provide-information-dangerous-atherosclerosis-plaque - 2025-10-17

All diabetics who developed the disease before the age of six months should be tested for a certain genetic mutation. Some of them might not need insulin injections but could manage their disease just as well, or better, with a simple tablet. “Neonatal diabetes is an uncommon form of diabetes caused by a genetic mutation, which means that insulin is not secreted in the right way”, says Sten Ivarss

https://www.ludc.lu.se/article/many-diabetics-could-manage-without-insulin-injections - 2025-10-17

A prestigious award to Olle Melander, researcher at Lund University Diabetes Centre and physician at Skåne University Hospital in Malmö. He is awarded the prestigious award Peter Sleight Award 2010. The award, which is handed out by the European Society of Hypertension, consists apart from the honor, also by 10.000 euro.- It is of course very honorable to get appreciation for what you do and that

https://www.ludc.lu.se/article/prestigious-award-cardiovascular-research - 2025-10-17

During regulation of blood glucose levels, various hormones interact and counteract with each other in a complex manner. Together, these hormones maintain stable glucose levels. The recent mapping of hormonal interactions, carried out by scientists at Lund University Diabetes Centre (LUDC), aimed to explain why an imbalance occurs and to increase our understanding of the causes of diabetes. Insuli

https://www.ludc.lu.se/article/stable-glucose-levels-are-result-complex-hormonal-balancing-act - 2025-10-17

For the first time, scientists are able to describe the exact mechanism for how a common genetic variant leads to a disruption in blood lipid levels that significantly increases the risk of heart disease. The one in every three persons who carries both copies of the risk allele engages a 40 percent higher risk of suffering a heart attack than persons who do not carry either copy of the risk allele

https://www.ludc.lu.se/article/mechanism-behind-common-heart-attack-gene-explained-scientific-breakthrough-nature - 2025-10-17