Chiral building blocks are needed for the production of drugs and fine chemicals, which requires the use of several synthetic routes to produce a specific enantiomer of interest. One promising approach to introduce chirality into molecules is the stereo-selective whole cell bioreduction of carbonyl compounds or ketones to the corresponding chiral alcohols. The aim of this thesis was to develop ef

This paper introduces the design of a new multiphase clock generator with no feedback loop. A single-stage direct interpolation architecture is proposed. A 1/4 frequency divider and a short-circuit current suppression interpolator are developed to achieve the precise interpolation. The circuit has been fabricated in a standard 0.35 μm, 3.3 V CMOS process. The multiphase clock generator can operate

A variant of the compatrison theory of metaphor is put forward. The main points are (a) a theory of metaphor belongs to semantics, not pragmatics, (b) a metaphorical statement is a similarity statement, usually comparing descriptions of objects, (c) a metaphor is a constellation of words connected by a certain kind of relation - the metaphorical link, (d) metaphors are not necessarily asymmetric,

An edition of the consecration sermons in Gothenburg Cathedral 1633 by Superintendent Andreas Johannis Prytz, with introductory comments. The first sermon deals with the need for Church buildings, the second with the consecration of a new Church.

Biological diversity encompasses the genetic diversity within each species, the range of species in a given ecosystem e.g. species diversity and the diversity of ecosystems across an entire region (Primack, 2000). At present 1 per cent of the world’s described species are threatened with extinction. The most pervasive and overriding threat is habitat loss and degradation due to human activity such

Popular Abstract in Swedish Att få inopererat en höft- eller knäprotes är numera ett vanligt ingrepp. Under 80-talet visade svenska och utländska studier att 10-15% av de patienter som genomgick en sådan höftoperation drabbades av försämrad njurfunktion efter operationen. Denna försämring var övergående men kunde vara allvarlig för patienten, och kostsam för sjukvården, under den tid den kvarstod.Total hip replacement (THR) is a common procedure, generally performed in elderly persons. Previous studies indicated that the use of isoxazolyl penicillins could induce a transient post-operative renal dysfunction in these patients. By measuring urinary levels of markers for glomerular (albumin, IgG) and tubular (protein HC) function we studied the influence of systemic cloxacillin, the gentamic

We believe that a useful kinetic-energy functional should not only incorporate known limiting forms but also have accurate functional derivatives, so that it can be used for obtaining the correct ground-state density via variational calculations. Furthermore, an accurate functional for the kinetic energy should be obtained by fitting to smooth pseudoelectron systems rather than to all-electron cal

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