Multiple studies have described associations between infiltrating immune cells and prognosis in cancer; however, the clinical relevance has most often been attributed to the T-cell linage. This study aimed to further investigate the clinicopathological correlates and prognostic impact of B cell and plasma cell infiltration in CRC. Immunohistochemical expression of CD20, CD138 and immunoglobulin ka

Background: It remains unclear whether the increased risk of colorectal cancer (CRC) associated with obesity differs by gender, distribution of fat, tumour location and clinical (TNM) stage. The primary aim of this study was to examine these associations in 584 incident colorectal cancer cases from a Swedish prospective population-based cohort including 28098 men and women. Methods: Seven anthropo

What does it mean to feel suspense? What kinds of situations give rise to the emotion? What is the connection between suspense and narrativity? And how is it that we can feel suspense upon repeat encounters with the same narrative? These questions are at the center of the first part of this study, where I develop and defend the ‘imminence theory of suspense’. Central to this theory is the claim th

Harmonic periods have wide applicability in industrial real-time systems. Rate monotonic (RM) is able to schedule task sets with harmonic periods up to 100% utilization. Also, if there is no release jitter and execution time variation, RM and EDF generate the same schedule for each instance of a task. This property decreases the jitters which happen during sampling and actuation of the tasks, and

The thesis explores the obligation in international law to protect the ecological integrity of transboundary watercourses. The thesis specifically examines the obligation to protect environmental flows, which essentially means to protect a certain water flow for the benefit of freshwater ecosystems and the ecosystem services they supply. The obligation to protect the integrity of transboundary watThe thesis explores the obligation in international law to protect the ecological integrity of transboundary watercourses. The thesis specifically examines the obligation to protect environmental flows, which essentially means to protect a certain water flow for the benefit of freshwater ecosystems and the ecosystem services they supply. The obligation to protect the integrity of transboundary wat

Road haulage operations in general, and distribution in particular, are inefficient. Given the societal importance of road haulage and the low efficiency of the sector, road hauliers need to improve their operations and systematically tackle inefficiencies. However, the real causes of these inefficiencies, the “root causes”, have not been sufficiently examined in previous studies. This paper expanRoad haulage operations in general, and distribution in particular, are inefficient. Given the societal importance of road haulage and the low efficiency of the sector, road hauliers need to improve their operations and systematically tackle inefficiencies. However, the real causes of these inefficiencies, the “root causes”, have not been sufficiently examined in previous studies. This paper expan

Projektet HITS/Transparens utforskar hur frivillig användning av informations- och kommunikationsteknologi av privata aktörer kan förbättra informationstransparens i transport av farligt gods. Detta tillvägagångssätt skiljer sig från en lång rad projekt som sedan 80-talet haft ett centralt myndighetsperspektiv på informationshantering kring farligt gods. I linje med tidigare resultat inom forsknin

Species with similar resource requirements are commonly assumed to competitively exclude each other, unless they differentiate their ecological niches. Hence, parasitoid wasps that use the same host species need to find some way to avoid competition. The aim of this study was to identify the role of volatile cues from oilseed rape plants and the larval host in niche separation between three coexis

The amphibian fauna of the Central Menabe region in Western Madagascar is important in respect to their extraordinary adaptations to the dry forest habitat. This habitat is highly threatened. Until 1990, the dry forest in the west of the island was thought to have been reduced to only 3% of its original extent. New analyses show that this deforestation was ongoing at an alarming rate also in the l

This thesis investigates the coupling between moisture, heat, and deformation in paperboard. The presented investigations are primarily conducted via macroscale continuum modeling but experimental characterisations are also made. The continuum modeling is presented in a mixture theory framework where the paperboard is considered as a porous media composed of three immiscible phases; a network of c

Objectives. The Nordic Consortium for Acute Type A Aortic Dissection (NORCAAD) is a collaborative effort of Nordic cardiac surgery centers to study acute type A aortic dissection (ATAAD). Here, we outline the overall objectives and the design of NORCAAD. Design. NORCAAD currently consists of eight centers in Denmark, Finland, Iceland and Sweden. Data was collected for patients undergoing surgery f

Objective: To investigate the influence of cardiovascular risk factors, including fasting plasma glucose (FPG), on the association between electrocardiographic (ECG) and echocardiographic left ventricular hypertrophy (LVH) in an elderly population. Methods: We tested cross-sectional associations between electrocardiographic and echocardiographic LVH, defining LVH according to the Sokolow-Lyon volt

A chemically defined diet is a useful tool for the study of nutritional physiology of organisms. We have developed such a diet for Camponotus carpenter ants to facilitate experiments on nutritional requirements of these ants. Worker colonies of Camponotus floridanus were fed with a chemically defined diet, containing all essential minerals, amino acids, vitamins, growth factors and sucrose in an a

Optical measurement techniques have proven to be useful tools for studying combustion-related phenomenon. The fact that the techniques are optical facilitates performing the measurements without impinging upon the measurement object, such as the combustion event that can be involved. Such techniques can be species-specific and be performed in situ, i.e. in the setting in which the phenomena in que

Background: Carpenter ants (genus Camponotus) are considered to be omnivores. Nonetheless, the genome sequence of Blochmannia floridanus, the obligate intracellular endosymbiont of Camponotus floridanus, suggests a function in nutritional upgrading of host resources by the bacterium. Thus, thestrongly reduced genome of the endosymbiont retains genes for all subunits of a functional urease, as well