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High Iron Requirements for Growth in the Nuisance Alga Gonyostomum semen (Raphidophyceae)

The bloom-forming freshwater alga Gonyostomum semen is associated with acidic, mesotrophic brown water lakes in boreal regions. However, researchers have been unable to conclusively link G. semen abundance and bloom formation to typical brown water lake traits, that is, high water color and DOC (dissolved organic carbon) concentrations. Iron is a main driver of water color in boreal lakes, and a r

Active bacterial modification of the host environment through RNA polymerase II inhibition

Unlike pathogens, which attack the host, commensal bacteria create a state of friendly coexistence. Here, we identified a mechanism of bacterial adaptation to the host niche, where they reside. Asymptomatic carrier strains were shown to inhibit RNA polymerase II (Pol II) in host cells by targeting Ser2 phosphorylation, a step required for productive mRNA elongation. Assisted by a rare, spontaneous

The utility of lung weight to heart weight ratio as a means to identify suspected drug intoxication deaths in a medico-legal autopsy population

Fatal intoxications are common in a medico-legal autopsy setting and are associated with sparse findings during autopsy. It has been suggested that an increased lung weight may be associated with such fatalities. Previous literature is generally limited to a descriptive approach, including only opioid deaths, and lacking a definition of “heavy” lungs. Our aim was to create a model to identify case

The need for boundary spanners in an offshore insourcing strategy

This paper presents research on the need for boundary spanners in organizations that has an offshore insourcing strategy for the IT-function. The research question addressed was: How does an offshore insourcing strategy influence the need for having boundary spanners? Empirical data was collected using a case study in three phases, including semi-structured and structured interview in a multinatio

Developing urban tourism in green infrastructure

Urban tourism depends on the place specific qualities of destinations. In many cities, climate change poses a threat to these qualities, through increasing risk of excessive heat, draught and flooding. Cities need to adapt to reduce these risks. One way of doing this is to improve their green infrastructure. Urban forests, parks, rivers and wetlands may help reduce the effects of climate change in

Surgical management of hemorrhagic retinal detachment secondary to peripheral exudative hemorrhagic chorioretinopathy

The purpose of the study is to report a case of peripheral exudative hemorrhagic chorioretinopathy (PEHCR), managed surgically with favorable visual outcome. A 66-year-old female presented with painless visual loss due to dense vitreous and subretinal hemorrhage extending from the far periphery to the macula. Pars plana vitrectomy (PPV) with subretinal tissue plasminogen activator (TPA) injection

APG: A novel python-based ArcGIS toolbox to generate absence-datasets for geospatial studies

One important step in binary modeling of environmental problems is the generation of absence-datasets that are traditionally generated by random sampling and can undermine the quality of outputs. To solve this problem, this study develops the Absence Point Generation (APG) toolbox which is a Python-based ArcGIS toolbox for automated construction of absence-datasets for geospatial studies. The APG

Finns det kvinnliga astronauter? : Om könsneutral och inkluderande översättning av faktaböcker för barn

Are There Any Female Astronauts? On Gender-Inclusive Translation of Non-Fiction Books for ChildrenThis article deals with gender-inclusive translation of information books for children. Translation solutions drawn from three non-fiction books translated from French to Swedish by different translators are discussed in terms of gender neutrality and inclusion. Analysis reveals that, although the SweAre There Any Female Astronauts? On Gender-Inclusive Translation of Non-Fiction Books for ChildrenThis article deals with gender-inclusive translation of information books for children. Translation solutions drawn from three non-fiction books translated from French to Swedish by different translators are discussed in terms of gender neutrality and inclusion. Analysis reveals that, although the Swe

Impacts of litter decay on organic leachate composition and reactivity

Litter decomposition produces labile and recalcitrant forms of dissolved organic matter (DOM) that significantly affect soil carbon (C) sequestration. Chemical analysis of this DOM can provide important knowledge for understanding soil DOM dynamics, but detailed molecular analyses on litter derived DOM are scarce. Here we use ultrahigh resolution mass spectrometry (FT-ICR MS) to characterize the m

Genomic and transcriptomic characterization of desmoplastic small round cell tumors

Desmoplastic small round cell tumor (DSRCT) is a highly aggressive soft tissue tumor primarily affecting children and young adults. Most cases display a pathognomonic EWSR1-WT1 gene fusion, presumably constituting the primary driver event. Little is, however, known about secondary genetic changes that may affect tumor progression. We here studied 25 samples from 19 DSRCT patients using single nucl

Local Contrasts in Concentration of Ambient Particulate Air Pollution (PM2.5) and Incidence of Alzheimer's Disease and Dementia : Results from the Betula Cohort in Northern Sweden

Exposure to fine particulate air pollution (PM2.5) is emerging as a risk factor for Alzheimer's disease (AD), but existing studies are still limited and heterogeneous. We have previously studied the association between dementia (AD and vascular dementia) and PM2.5 stemming from vehicle exhaust and wood-smoke in the Betula cohort in Northern Sweden. The aim of this commentary is to estimate the ass

Clarifying and expanding the theory typology : A reply to readers’ comments

We all want to develop impactful and valuable theories, but what do we mean by ‘theory’? In this piece, we reply to the four readers’ comments on a recent paper in which we propose a theory typology that, in comparison to existing literature, offers a considerably broader, more pluralistic and, at the same time, more precise definition of the meaning(s) of ‘theory’ within academia. In their commen

Cyclohexyl-α maltoside as a highly efficient tool for membrane protein studies

Membrane proteins (MPs) constitute a large fraction of the proteome, but exhibit physicochemical characteristics that impose challenges for successful sample production crucial for subsequent biophysical studies. In particular, MPs have to be extracted from the membranes in a stable form. Reconstitution into detergent micelles represents the most common procedure in recovering MPs for subsequent a