Solution phase synthesis of a constrained Leu(5)-enkephalin amide analogue 10 is reported, in which the cyclic ferrocenyl containing subunit 7 was introduced as a mimetic of the tetrapeptide Tyr-Gly-Gly-Phe unit. Temperature dependence of the chemical shift of the amide protons of 10 indicated a hydrogen bond between the same amino acid residues as observed for the natural Leu-enkepalin in the sin

Objective. To validate self-reported smoking habits in smoking pregnant women and estimate the prevalence of substantial exposure to passive smoking in non-smoking pregnant women. Design. Retrospective, quantitative study, consecutively collected samples. Setting. One antenatal clinic in Blekinge County, Sweden. Subjects. 509 pregnant women. Method. Information about smoking habits were taken from

Popular Abstract in Swedish I blodet finns röda och vita blodkroppar eller blodceller, som är nödvändiga för vår överlevnad. Blodcellerna utvecklas i benmärgen från gemensamma ursprungsceller, så kallade stamceller och en konstant nyproduktion pågår genom hela livet. Under produktionen av mogna celler tillväxer och delar sig cellerna och får allt mer specialiserade egenskaper. Denna specialiseringAll hematopoietic cells are derived from the hematopoietic stem cells (HSCs) in a continuous and dynamic process, regulated by a network of transcription factors in different combinations and extrinsic signals from growth factors (GFs) and other factors in the microenvironment. In the initial stages of hematopoiesis HSCs differentiate to progenitor cells with gradually more restricted lineage pote

A 10-bit 5-MS/s successive approximation ADC cell and a 70-MS/s parallel ADC array based on this cell, designed and fabricated in a 1.2-?m CMOS process, are presented. The ADC cell was designed to have an input bandwidth of more than 35 MHz and a sampling time of 14 nS at a clock rate of 70 MHz. The parallel ADC array consists of 14 such cells which are timed in one clock cycle skew successively i

REX-ISOLDE is an experiment at ISOLDE/CERN with the aim to study the nuclear structure of neutron-rich nuclei using radioactive ion beams up to 2.2 MeV/u. The highly-efficient gamma-ray detector set-up MINIBALL will be used to explore reactions induced by Coulomb excitation or neutron transfer.

Aims: Guidelines for cardiovascular disease (CVD) prevention cite high levels of low-density lipoprotein cholesterol (LDL-C) as a major risk factor and recommend LDL-C goals for various risk groups. Lifestyle changes are advised as first-line treatment for patients with high cholesterol, and statins are recommended in high-risk patients. The From The Heart study investigated current practice for t

An account of the electronic structure of AmF3 and AmCl3 has been obtained by Complete Active Space calculations (CASSCF and CASPT2) using either a scalar Douglas-Kroll-Hess Hamiltonian or a relativistic effective core potential. It has been compared to the description obtained by density functional theory (DFT) methods combined with a quasi-relativistic ZORA approach, either in the scalar or two-

An assessment of impacts on Arctic terrestrial ecosystems has emphasized geographical variability in responses of species and ecosystems to environmental change. This variability is usually associated with north-south gradients in climate, biodiversity, vegetation zones, and ecosystem structure and function. It is clear, however, that significant east-west variability in environment, ecosystem str

The aim of this thesis was to study onlay bone grafting in the adult rat to improve graft incorporation and perservation of graft size. In 167 adult isogeneic lewis rats, the size maintenance and bone formation at the graft-host interface of uni- and bicortical onlays positioned in various environments and treatments were investigated. The findings were assessed after four, 12 and 20 weeks with ro

Recently, Hilhorst (2000) presented a theoretical model describing a linear relationship between bulk electrical conductivity, sigma(a), and dielectric constant, K-a, in moist soil. Hilhorst (2000) found that using this linear relationship, measurements of the pore water electrical conductivity, sigma(p), can be made in a wide range of soil types without soil-specific calibrations. If accurate mea

We present new results for the inner valence levels of clusters of the three inert gases Ar, Kr and Xe based on photoelectron spectroscopy studies. The inner valence levels are compared to the localised core levels and to the delocalised outer valence levels. This comparison shows a gradual change from a relatively localised behaviour for Ar inner valence 3s, over the intermediate case of Kr inner

Purpose: Interstitial temperature mapping was used to determine the heat field within the prostate by the Coretherm. (ProstaLund, Lund, Sweden) transurethral microwave thermotherapy device. Gadolinium. enhanced magnetic resonance imaging (MRI) and histopathology were used to determine the extent and pattern of coagulation necrosis following treatment. The cell kill assessment feature of the device

In this paper, enhancement of the signal root estimation of a particular kind of real-valued two-dimensional (2-D) sinusoidal modes is considered. To its constitution, each mode corresponds to the superposition of two real-valued plane waves in a particular symmetry. The concept of partial forward-backward averaging, which is applicable for modes that are undamped in at least one dimension, is int