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Bonusbarnbarn och bonusförföräldrar : Om omsorgsrelationer mellan generationer i ombildade och valda familjer
Förföräldrar, det vill säga far- och morföräldrar, spelar en allt viktigare roll som omsorgspersoner i sina barnbarns liv även i välfärdsstater som Sverige (Bordone et al., 2023; Zanasi et al., 2023). Samtidigt innebär ökande separationer och ombildningar av parrelationer både bland föräldrar och bland förföräldrar att allt fler befinner sig i bonusrelationer (Guzzo, 2016; Lowenstein, 2005). BonusGrandparents play an increasingly significant role as caregivers in their grandchildren's lives, even in welfare states like Sweden (Bordone et al., 2023; Zanasi et al., 2023). Concurrently, the rise in separations and reconstitutions of partnerships, both among parents and grandparents, has led to an increase in step-relationships (Guzzo, 2016; Lowenstein, 2005). Step-grandparenting and step-gran
Protective Non-neutralizing anti-N-terminal Domain mAb Maintains Fc-mediated Function against SARS-COV-2 Variants up to BA.2.86-JN.1 with Superfluous In Vivo Protection against JN.1 Due to Attenuated Virulence
Substantial evidence supports that Fc-mediated effector functions of anti-spike Abs contribute to anti-SARS-Cov-2 protection. We have previously shown that two non-neutralizing but opsonic mAbs targeting the receptor-binding domain and N-terminal domain (NTD), Ab81 and Ab94, respectively, are protective against lethal Wuhan SARS-CoV-2 infection in K18-hACE2 mice. In this article, we investigated w
Protective non-neutralizing SARS-CoV-2 monoclonal antibodies
Recent studies show an important role for non-neutralizing anti-spike antibodies, including monoclonal antibodies (mAbs), in robustly protecting against SARS-CoV-2 infection. These mAbs use Fc-mediated functions such as complement activation, phagocytosis, and cellular cytotoxicity. There is an untapped potential for using non-neutralizing mAbs in durable antibody treatments; because of their avai
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The densest stellar systems in the Universe: The nuclear stellar disc
Understanding the formation and evolution of galaxies and in particular their galactic centres is one of the most intriguing questions in modern astrophysics. Many spiral galaxies like the Milky Way feature a nuclear stellar disc (NSD) in their centre. The Milky Way's NSD is, together with the nuclear star cluster and the central super massive black hole, one of the main inner components and best
Reimagining Species Relations : A Decade of Studying and Teaching Critical Animal Studies at Lund University
The year 2022 marked the 10th anniversary of the course Critical Animal Studies: Animals in Society, Culture and the Media at the Department of Communication and Media at Lund University. As the first initiative of its kind in Sweden, the course explores the shifting roles and positions of non-human animals in today’s complex societies. It aims to equip students with analytical tools to critically
Relational Work in Rural Tourism Enterprising: Navigating In-between the Formal and the Informal
Small-scale tourism enterprises are central actors in the rural labour market as facilitators of job opportunities, sustained business relationships, collaborations, and the development of resilient work relationships. These enterprises navigate in a market characterised by social and economic complexity where work is performed by a diverse workforce. The relational work performed in such enterpri
Conformational control of antimicrobial peptide amphiphilicity : consequences for boosting membrane interactions and antimicrobial effects of photocatalytic TiO2 nanoparticles
This study reports on the effects of conformationally controlled amphiphilicity of antimicrobial peptides (AMPs) on their ability to coat TiO2 nanoparticles (NPs) and boost the photocatalytic antimicrobial effects of such NPs. For this, TiO2 NPs were combined with AMP EFK17 (EFKRIVQRIKDFLRNLV), displaying a disordered conformation in aqueous solution but helix formation on interaction with bacteri
Novel diagnostic methods and potential treatments in cardiovascular autonomic dysfunction
General Aim: To investigate novel diagnostic tools and treatment options for cardiovascular autonomic dysfunction (CVAD) patients, focusing on syncope, orthostatic intolerance, and heart failure (HF).Background: CVAD includes common clinical entities such as vasovagal syncope (VVS) postural orthostatic tachycardia syndrome (POTS) and orthostatic hypotension (OH). Also, CVAD plays an important role
To wear or not to wear, was that the question? Understanding citizen responses to COVID-19 crisis management in social media across Europe
This study aims to gain qualitative insights about and compare public responses to COVID-19 crisis management during the different pandemic phases and across three countries—Norway, Sweden and Italy. To do so, we have carried out a qualitative content analysis of a selection of 2606 tweets containing the term ‘face mask’ in Italian, Norwegian, and Swedish published between March 1, 2020 and June 3
Climate Change Mitigation, Adaptation, and Resilience : Challenges and Opportunities for the Control Systems Community
Climate change poses an existential threat to humanity. It is now indisputable that the primary cause of this threat is human activity resulting in high greenhouse gas (GHG) emissions, which began during the Industrial Revolution and have continued to rapidly accelerate. The first warnings of impending and irreversible climate change were sounded decades ago, when governmental and intergovernmenta
Distinct Infiltration of T Cell Populations in Bladder Cancer Molecular Subtypes
Bladder cancer is a heterogenous disease, and molecular subtyping is a promising method to capture this variability. Currently, the immune compartment in relation to subtypes is poorly characterized. Here, we analyzed the immune compartment in bladder tumors and normal bladder urothelium with a focus on T cell subpopulations using flow cytometry and RNA sequencing. The results were investigated in
Beauville Structures for Quotients of Generalised GGS-groups
A finite group with a Beauville structure gives rise to a certain compact complex surface called a Beauville surface. Gül and Uria-Albizuri showed that quotients of the periodic Grigorchuk–Gupta–Sidki (GGS-)groups that act on the p-adic tree, for p an odd prime, admit Beauville structures. We extend their result by showing that quotients of infinite periodic GGS-groups acting on pn-adic trees, for
Informed consent to midwifery practices and interventions during the second stage of labor -An observational study within the Oneplus trial
Objectives To study informed consent to midwifery practices and interventions during the second stage of labor and to investigate the association between informed consent and experiences of these practices and interventions and women's experiences of the second stage of labor. Methods This study uses an observational design with data from a follow-up questionnaire sent to women one month after giv
Primary central nervous system lymphomas : EHA–ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up☆
Unraveling the Binding Mode of Cyclic Adenosine–Inosine Monophosphate (cAIMP) to STING through Molecular Dynamics Simulations
The stimulator of interferon genes (STING) plays a significant role in immune defense and protection against tumor proliferation. Many cyclic dinucleotide (CDN) analogues have been reported to regulate its activity, but the dynamic process involved when the ligands activate STING remains unclear. In this work, all-atom molecular dynamics simulations were performed to explore the binding mode betwe
Climate Impact on Dissolved Organic Carbon Composition in a North-Temperate Peatland and Recipient Surface Water
Climate may regulate dissolved organic carbon (DOC) composition across the peat-water interface, but experimental evidence is scarce. We manipulated the climate in peatland and recipient surface water mesocosms to reflect four different climate warming scenarios. In half of the mesocosms, the water level was managed to avoid drought, after which responses were recorded during two annual cycles. It
χc2 tensor meson transition form factors in the light front approach
We continue our work on the light-front formulation of quarkonium γ∗γ transition form factors, extending the formalism to JPC = 2++ tensor meson states. We present an analysis of γ∗γ → χc2 transition amplitude and the pertinent helicity form factors. Our relativistic formalism is based on the light-front quark-antiquark wave function of the quarkonium. We calculate the two-photon decay width as we
VELOcities of CEpheids (VELOCE) : I. High-precision radial velocities of Cepheids
We present the first data release of VELOcities of CEpheids (VELOCE), dedicated to measuring the high-precision radial velocities (RVs) of Galactic classical Cepheids (henceforth, Cepheids). The first data release (VELOCE DR1) comprises 18 225 RV measurements of 258 bona fide classical Cepheids on both hemispheres collected mainly between 2010 and 2022, along with 1161 observations of 164 stars, m