Genetic organization of encapsulated and non-encapsulated Haemophilus influenzae strains. Analysis of the glpTQ and 23S rRNA operons
Encapsulated Haemophilus influenzae type b (Hib) and non-encapsulated H. influenzae (NTHi) are important pathogens causing invasive and mucosal infections in children. A 42 kDa surface-exposed lipoprotein, protein D, has been found to be a potential virulence factor of NTHi. The gene encoding protein D (hpd) is homologous to the glpQ gene encoding glycerophosphodiester phosphodiesterase in Escheri