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ZnO nanocrystals on SiO2/Si surfaces thermally cleaned in ultrahigh vacuum and characterized using spectroscopic photoemission and low energy electron microscopy

Thermal cleaning in ultrahigh vacuum of ZnO nanocrystals distributed on SiO2/Si surfaces has been studied using spectroscopic photoemission and low energy electron microscopy (SPELEEM). This study thus concern weakly bound ZnO nanocrystals covering only 5%-10% of the substrate. Chemical properties, crystallinity, and distribution of nanocrystals are used to correlate images acquired with the diffe

Azimuthal Anisotropy of pi(0) Production in Au plus Au Collisions at root s(NN)=200 GeV: Path-Length Dependence of Jet Quenching and the Role of Initial Geometry

We have measured the azimuthal anisotropy of pi(0) production for 1 < p(T) < 18 GeV/c for Au + Au collisions at root s(NN) = 200 GeV. The observed anisotropy shows a gradual decrease for 3 less than or similar to p(T) less than or similar to 7-10 GeV/c, but remains positive beyond 10 GeV/c. The magnitude of this anisotropy is underpredicted, up to at least similar to 10 GeV/c, by current perturbat

Biogrid-a microfluidic device for large-scale enzyme-free dissociation of stem cell aggregates.

Culturing stem cells as free-floating aggregates in suspension facilitates large-scale production of cells in closed systems, for clinical use. To comply with GMP standards, the use of substances such as proteolytic enzymes should be avoided. Instead of enzymatic dissociation, the growing cell aggregates may be mechanically cut at passage, but available methods are not compatible with large-scale

Strategy for detection of prostate cancer based on relation between prostate specific antigen at age 40-55 and long term risk of metastasis: case-control study

Objective To determine the association between concentration of prostate specific antigen (PSA) at age 40-55 and subsequent risk of prostate cancer metastasis and mortality in an unscreened population to evaluate when to start screening for prostate cancer and whether rescreening could be risk stratified. Design Case-control study with 1: 3 matching nested within a highly representative population

Effects of color reconnection on hadron flavor observables

We present a series of observables for soft inclusive physics, and utilize them for comparison between two recently developed color reconnection models: the new color reconnection model in Pythia and the DIPSY rope hadronization model. The observables are ratios of identified hadron yields as a function of the final-state activity, as measured by the charged multiplicity. Since both considered mod

Plant communities and the reproductive success of native plants after the invasion of an ornamental herb

The effects of plant invasions on plant communities are often assessed at a few sites or in a particular type of habitat, while studies in different habitat types are scarce. We investigated plant communities in the presence and absence of the invasive ornamental herb, Lupinus polyphyllus, in four habitat types: meadow, forest, road verge and wasteland, in two geographic regions by comparing vascu

Ser129D mutant alpha-synuclein induces earlier motor dysfunction while S129A results in distinctive pathology in a rat model of Parkinson's disease

Alpha-synuclein phosphorylated at serine 129 (S129) is highly elevated in Parkinson's disease patients where it mainly accumulates in the Lewy bodies. Several groups have studied the role of phosphorylation at the S129 in alpha-synuclein in a rat model for Parkinson's disease using recombinant adeno-associated viral (rAAV) vectors. The results obtained are inconsistent and accordingly the role of

Hemochromatosis (HFE) gene mutations and risk of gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) study

Hereditary hemochromatosis (HH) is a strong risk factor for hepatocellular cancer, and mutations in the HFE gene associated with HH and iron overload may be related to other tumors, but no studies have been reported for gastric cancer (GC). A nested casecontrol study was conducted within the European Prospective Investigation into Cancer and Nutrition (EPIC), including 365 incident gastric adenoca

Valence photoionization and resonant Auger decay of Sb-4 clusters at resonances below the 4d ionization threshold

The valence photoionization and resonant Auger decay at 4d resonances below the 4d ionization threshold in Sb-4 clusters have been studied experimentally by means of photoelectron spectroscopy. The 4d absorption spectrum in the photon energy region from 30 to 36 eV has been recorded using the constant ionic state (CIS) partial electron yield (PEY), and the CIS spectra for various ionic states are

Fish consumption and mortality in the European Prospective Investigation into Cancer and Nutrition cohort

Fish is a source of important nutrients and may play a role in preventing heart diseases and other health outcomes. However, studies of overall mortality and cause-specific mortality related to fish consumption are inconclusive. We examined the rate of overall mortality, as well as mortality from ischaemic heart disease and cancer in relation to the intake of total fish, lean fish, and fatty fish

Behavior of relative state selective photoionization cross sections of RbBr molecules in the valence region

The photon energy dependence of relative photoionization cross sections in the valence ionization energy region of 5 to 45 eV for 4p and 4s orbitals of Rb and Br ions in RbBr vapors has been investigated. The behavior of state selective cross sections of molecular valence orbitals has been analyzed by comparing the observed 4p to 4s photoelectron intensity branching ratios with atomic state select

Immunizations with unmodified tumor cells and simultaneous COX-2 inhibition eradicate malignant rat brain tumors and induce a long-lasting CD8(+) T cell memory.

Malignant brain tumors induce pronounced immunosuppression, which diminishes immune responses generated by immunotherapy. Here we report that peripheral immunotherapy, using irradiated unmodified whole tumor cells, and systemic cyclooxygenase-2 inhibition induce cure in glioma-bearing rats (60% cure rate), whereas neither monotherapy was sufficient to cure any animal. Moreover, the combined therap

Distributed Dynamic Reinforcement of Efficient Outcomes in Multiagent Coordination and Network Formation

We analyze reinforcement learning under so-called "dynamic reinforcement." In reinforcement learning, each agent repeatedly interacts with an unknown environment (i.e., other agents), receives a reward, and updates the probabilities of its next action based on its own previous actions and received rewards. Unlike standard reinforcement learning, dynamic reinforcement uses a combination of long-ter

Cancer cell differentiation heterogeneity and aggressive behavior in solid tumors.

The differentiation stage of tumors is a central aspect in the histopathological classification of solid malignancies. The differentiation stage is strongly associated with tumor behavior, and generally an immature tumor is more aggressive than the more differentiated counterpart. While this is common knowledge in surgical pathology, the contribution of differentiation-related gene expression and

Cancer Cell Radiobiological Studies Using In-House-Developed α-Particle Irradiator.

An α-particle irradiator, enabling high-precision irradiation of cells for in vitro studies, has been constructed. The irradiation source was a (241)Am source, on which well inserts containing cancer cells growing in monolayer were placed. The total radioactivity, uniformity, and α-particle spectrum were determined by use of HPGe detector, Gafchromic™ dosimetry film, and PIPS(®) detector measureme

Mode 2 and the tension between excellence and utility: The case of a policy-relevant research field in Sweden

This paper investigates the impact of changing science policy doctrines on the development of an academic field, working life research. Working life research is an interdisciplinary field of study in which researchers and stakeholders collaborated to produce relevant knowledge. The development of the field, we argue, was both facilitated and justified by the, at the time dominant, science policy o