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Structure of the Lysinibacillus sphaericus Tpp49Aa1 pesticidal protein elucidated from natural crystals using MHz-SFX.

The Lysinibacillus sphaericus proteins Tpp49Aa1 and Cry48Aa1 can together act as a toxin toward the mosquito Culex quinquefasciatus and have potential use in biocontrol. Given that proteins with sequence homology to the individual proteins can have activity alone against other insect species, the structure of Tpp49Aa1 was solved in order to understand this protein more fully and inform the desig

Flood analysis and protection system : Application to The Hongru River

The definition of a decision support system(DSS) may be : human-computer interactive software system to solve semi-structured decisional problems for decisional makers with data utilizing, information management, knowledge, as well as model techniques. DSS only provide supporting information about making decision for the decision maker without stipulate the decision itself. Decision is made by hum

The Cerebellar Mutism Syndrome : Risk Assessment, Prevention and Treatment

Cerebellar mutism syndrome (CMS) has received increasing attention over the last decades as a complication of posterior fossa tumour surgery in children. Risk factors, aetiological aspects, and treatment measures of the syndrome have been investigated, yet the incidence of CMS remains unchanged. Overall, we are currently able to identify patients at risk, but we are unable to prevent it from occur

High-resolution comparative atomic structures of two Giardiavirus prototypes infecting G. duodenalis parasite

The Giardia lamblia virus (GLV) is a non-enveloped icosahedral dsRNA and endosymbiont virus that infects the zoonotic protozoan parasite Giardia duodenalis (syn. G. lamblia, G. intestinalis), which is a pathogen of mammals, including humans. Elucidating the transmission mechanism of GLV is crucial for gaining an in-depth understanding of the virulence of the virus in G. duodenalis. GLV belongs to

Structure of the T=13 capsid of infectious pancreatic necrosis virus (IPNV)-a salmonid birnavirus

Birnaviruses infect a broad range of vertebrate hosts, including fish and birds, and cause substantial economic losses in the fishery and livestock industries. The infectious pancreatic necrosis virus (IPNV), an aquabirnavirus, specifically infects salmonids. While structures on T=1 subviral particles of the birnaviruses, including IPNV, have been studied, structural insights into the infectious T

Diffraction data from aerosolized Coliphage PR772 virus particles imaged with the Linac Coherent Light Source

Single Particle Imaging (SPI) with intense coherent X-ray pulses from X-ray free-electron lasers (XFELs) has the potential to produce molecular structures without the need for crystallization or freezing. Here we present a dataset of 285,944 diffraction patterns from aerosolized Coliphage PR772 virus particles injected into the femtosecond X-ray pulses of the Linac Coherent Light Source (LCLS). Ad

Deletion of fbiC in Streptomyces venezuelae removes autofluorescence in the excitation-emission range of cyan fluorescent protein

Autofluorescence poses an impediment to fluorescence microscopy of biological samples. In the Gram-positive, soil-dwelling bacteria of the genus Streptomyces, sources of autofluorescence have not been examined systematically to date. Here, we show that the model organism for the genus, Streptomyces venezuelae, shows autofluorescence in two of the commonly used fluorescence channels for visualizing

CMS-06THE NOPHO-EUROPEAN STUDY ON CEREBELLAR MUTISM SYNDROME (CMS)

BACKGROUND: The cerebellar mutism syndrome (CMS) is one of the most disabling late effects after neurosurgery for a posterior fossa tumour in childhood. The reported incidences vary substantially in previous studies. AIMS: Pathophysiology is unknown, but damage to cerebello-thalamo-cerebral circuits is likely. The study focuses on the risk factors for development and severity of CMS including surg

Genetics of circulating proteins in newborn babies at high risk of type 1 diabetes

Type 1 diabetes is a chronic, autoimmune disease characterized by the destruction of insulin-producing β-cells in the pancreas. Early detection can facilitate timely intervention, potentially delaying or preventing disease onset. Circulating proteins reflect dysregulated biological processes and offer insights into early disease mechanisms. Here, we construct a genome-wide pQTL map of 1985 protein

Gulf Women and Anti-European Imperialism : Forgotten Gender Discourses in Interwar Iran’s Shi’i Reformation Movement

Often treated as simply anti-modernism, a focus on three reformist figures with transnational intellectual ties—Shariat Sangelaji, Asadollah Kharaqani, and Muhammad Khalesizadeh—reveals how Iranian natives of the Gulf littoral contributed to reconstitute modern life by criticizing the global structures of power arising with European imperialism. Blurring the dichotomy of modern/traditional, Iran a

Witnessing against a divide? : An analysis of early Holocaust testimonies constructed in interviews between Jewish and non-Jewish Poles

This article makes visible and analyzes survivor testimonies gathered in interviews between Jewish and non-Jewish Polish survivors of Nazi persecution in Sweden in 1945–1946. By examining the content of the testimonies in relation to the distinct context, it contributes to research about early documentation efforts and their role in shaping Polish memory of the Holocaust as well as post-conflict r

Postoperative word-finding difficulties in children with posterior fossa tumours : a crosslinguistic European cohort study

PURPOSE: Posterior fossa tumour (PFT) surgery carries a risk of mutism or severely reduced speech. As for higher-cognitive language functions, word-finding difficulties have been reported, but no study has compared pre- and postoperative word-finding speeds to identify impairment caused by surgery. The current study investigated changes in word-finding ability associated with PFT surgery and exami

Witnessing the Suffering of Others in Watercolor and Pencil : Jadwiga Simon-Pietkiewicz’s Holocaust Art Exhibited in Sweden, 1945-46

In the Holocaust’s immediate aftermath (1945–1946), a small gallery in Lund, Sweden exhibited the paintings and drawings of Polish artist Jadwiga Simon-Pietkiewicz, which depicted her former fellow inmates in the Ravensbrück concentration camp. This exhibit and subsequent exhibitions elsewhere in Sweden marked rare instances of early postwar Holocaust art displayed in a country that had been relat

Evaluation of Real-Time Cardiovascular Flow MRI Using Compressed Sensing in a Phantom and in Patients With Valvular Disease or Arrhythmia

Background: Real-time (RT) phase contrast (PC) flow MRI can potentially be used to measure blood flow in arrhythmic patients. Undersampled RT PC has been combined with online compressed sensing (CS) reconstruction (CS RT) enabling clinical use. However, CS RT flow has not been validated in a clinical setting. Purpose: Evaluate CS RT in phantom and patients. Study Type: Prospective. Population: Flo

Formalism and Instrumentalism in the Marxist Critique of Right : With What Must Pashukanian Theory Begin?

The critique of the legal form of capitalism by E. B. Pashukanis has risen to prominence once again. However, the negative origin of the concept of the legal form, the critique of formalism and instrumentalism, has received too little attention. This essay substantiates the significance of Pashukanis’s critique, avoiding both overly general and narrow conceptions. Moreover, it proposes that his negThe critique of the legal form of capitalism by E. B. Pashukanis has risen to prominence once again. However, the negative origin of the concept of the legal form, the critique of formalism and instrumentalism, has received too little attention. This essay substantiates the significance of Pashukanis’s critique, avoiding both overly general and narrow conceptions. Moreover, it proposes that his ne

Dynamical arrest for globular proteins with patchy attractions

Attempts to use colloid science concepts to better understand the dynamic properties of concentrated or crowded protein solutions are challenging due to the fact that globular proteins generally have heterogeneous surfaces that result in anisotropic or patchy contributions to their interaction potential. This is particularly difficult when targeting non-equilibrium transitions such as glass and ge

Clarification and Modification of the International Contact Dermatitis Research Group Classification of Patch Test Reactions on Behalf of the International Contact Dermatitis Research Group

The first ICDRG (International Contact Dermatitis Research Group) classification of patch test reactions was published in 1970. With this classification, many weak reactions were classified as allergic reactions. A second classification was therefore implemented one decade later on behalf of the ICDRG and the North American Contact Dermatitis Group. This classification was adopted by the European

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Detta är nederländsk bearbetning och översättning av min svenska biografi om Kleopatra.

Wealth, Consumption, and Industriousness : Evidence from southern Sweden, 1570-1860

This dissertation utilizes a new dataset on the belongings of early modern households, gathered from southern Sweden, to map the development of wealth and material living standards over the course of the early modern period. Together, the four papers making up the main part of the dissertation depicts a significantly more economically dynamic early modern period – especially eighteenth century – tThis dissertation utilizes a new dataset on the belongings of early modern households, gathered from southern Sweden, to map the development of wealth and material living standards over the course of the early modern period. Together, the four papers making up the main part of the dissertation depicts a significantly more economically dynamic early modern period – especially eighteenth century – t