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Modeling and Simulations of Multiphysics Phenomena ad Performance in Proton Exchange Membrane Fuel Cells

Proton exchange membrane fuel cells (PEMFCs) are considered as the mostpromising alternative power sources with a wide variety of applications owing to their attractive advantages compared to other conventional power sources. During the past decades, the cell performance has been gradually improved. However, the cell performance improvement and cost reduction are still urgently needed due to the r

Predicting postoperative pain. Clinical and genetic studies of relationships between pain sensitivity and pain after surgery.

Trots den snabba utvecklingen av moderna tekniker för narkos och bedövning upplever många patienter smärta efter kirurgi. God smärtlindring efter en operation kan påskynda återhämtningen och därmed minska risken för komplikationer som blodpropp eller infektion. För att uppnå detta måste vi bli bättre på att hitta individer med ökad risk för postoperativ smärta redan innan de sövs. Sedan tidigare kMany patients experience pain after surgery. Postoperative pain may lead to delayed mobilization, persisting pain, and psychosocial distress. Others are given excessive analgesic doses and experience side effects. More optimal use of pain relief has several advantages, such as faster postoperative mobilization and fewer incidents of venous thromboembolism or infection. To achieve this, we must ide

Uncertainty and variation in LCA - Implementation of probabilistic methods to assess environmental impacts of infrastructures

For most applications trying to interpret the real world uncertainties will be an important factor to consider, which is also true for Life-Cycle Assessment used for estimating total environmental impact during the life-cycle of products, services, buildings, structures, roads etc. The construction and usage of infrastructure are major causes of emissions and energy use, thus making it even more i

Cross-Border Asset Holdings and Comovements in Sovereign Bond Markets

We analyze the importance of different asset holdings for the interdependence of the yield curves in the Euro area using a spatial VAR model. We find that the cross-border holdings of long-term debt and bank lending are important for the interdependence. We also find that comovement in the Euro area declines after 2008. We show that this decline is not related to the difference among countries in

Heritage language proficiency does not predict syntactic CLI into L3 English

This study examines cross-linguistic influence (CLI) in the acquisition of embedded wh-questions in L3 English in German-dominant heritage speakers (HSs) of Italian. Specifically, we investigate whether a higher proficiency in the heritage language Italian increases the potential for CLI from that language. To this end, 21 adult-aged Italian-German early bilinguals and 32 monolingual controls (L1

Switching ON Fetal B Lymphopoiesis

B-1a cells are innate-like lymphocytes that develop primarily during fetal and neonatal life, whereas adult bone marrow (BM) hematopoietic stem cells (HSCs) preferentially give rise to follicular B-2 cells. Functioning at the interface of the innate and adaptive immune systems, B-1a cells provide a non-redundant first line of defense prior to the temporally delayed establishment of a B-2 cell resp

Detection of Stance-Related Characteristics in Social Media Text

In this paper, we present a study for the identification of stancerelated features in text data from social media. Based on our previous work on stance and our findings on stance patterns, we detected stance-related characteristics in a data set from Twitter and Facebook. We extracted various corpus-, quantitative- and computational-based features that proved to be significant for six stance categ

Aerococcal infections - from bedside to bench and back

Bakteriesläktet Aerococcus består av åtta arter av s.k. Grampositiva kocker. Den första arten, A. viridans, beskrevs 1953 och kopplingar gjordes mellan den och en allvarlig sjukdom hos hummer. Det skulle dröja åtskilliga decennier innan nästa aerokockart, A. urinae, upptäcktes. Denna kopplades till urinvägsinfektioner (UVI) och bakteriemi, dvs. växt av bakterier i blodet, hos människa. Därefter haThe genus Aerococcus comprises eight species of Gram-positive cocci. The incidence and the clinical importance of aerococcal infections have been underestimated in the past, due to species identification difficulties. In our first study, we evaluated the usefulness of MALDI-TOF MS as a species identification method for aerococci and found that it had a high sensitivity and specificity. Two populat

Prednisolone treatment reduces the osteogenic effects of loading in mice

Glucocorticoid treatment, a major cause of drug-induced osteoporosis and fractures, is widely used to treat inflammatory conditions and diseases. By contrast, mechanical loading increases bone mass and decreases fracture risk. With these relationships in mind, we investigated whether mechanical loading interacts with GC treatment in bone. Three-month-old female C57BL/6 mice were treated with high-

Impaired functional vitamin B6 status is associated with increased risk of lung cancer

Circulating vitamin B6 levels have been found to be inversely associated with lung cancer. Most studies have focused on the B6 form pyridoxal 5′-phosphate (PLP), a direct biomarker influenced by inflammation and other factors. Using a functional B6 marker allows further investigation of the potential role of vitamin B6 status in the pathogenesis of lung cancer. We prospectively evaluated the assoc

Obesity and metabolic features associated with long-term developing diastolic dysfunction in an initially healthy population-based cohort

Background: Diastolic dysfunction (DD) is increasingly common. However, its metabolic determinants are poorly known. This study aims to determine which metabolic and inflammatory features predict DD in initially healthy adults. Methods: We prospectively analyzed the association between metabolic features and DD in 728 initially healthy adults aged 30–60 from Eastern France enrolled in the STANISLA

The influence of participation on mortality in very old age among community-living people in Sweden

Background: Participation in everyday life and society is generally seen as essential for health-related outcomes and acknowledged to affect older people’s well-being. Aims: To investigate if aspects of performance- and togetherness-related participation influence on mortality among very old single living people in Sweden. Methods: ENABLE-AGE Survey Study data involving single-living participants

Living and ageing with stroke : an exploration of conditions influencing participation in social and leisure activities over 15 years

Objective: To explore conditions influencing long-term participation in social and leisure activities among people who have had a stroke. Methods: This study had a qualitative design, using a grounded theory methodology. Data collection was based on in-depth interviews performed 15 years after a first-ever stroke with 10 persons recruited from a population-based stroke cohort in Sweden. The study

Oral and sublingual immunotherapy for egg allergy

Background: Clinical egg allergy is a common food allergy. Current management relies upon strict allergen avoidance. Oral immunotherapy might be an optional treatment, through desensitization to egg allergen. Objectives: To determine the efficacy and safety of oral and sublingual immunotherapy in children and adults with immunoglobulin E (IgE)-mediated egg allergy as compared to a placebo treatmen

Treatment according to guidelines may bridge the gender gap in outcome for patients with stage T1 urinary bladder cancer

Objective: The aim of this investigation was to study differences between male and female patients with stage T1 urinary bladder cancer (UBC) regarding intravesical instillation therapy, second resection and survival. Materials and methods: This study included all patients with non-metastatic primary T1 UBC reported to the Swedish National Register of Urinary Bladder Cancer (SNRUBC) from 1997 to 2