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Beta cell function is an important factor in the development of both Type 1 (T1D) and Type 2 (T2D) diabetes mellitus. T1D is characterized by a primary defect in insulin secretion due to the immune-mediated beta cell destruction, however, the more common T2D beside insulin resistance also include impaired beta cell function as a consequence to abnormal glucose homeostasis. Genetic susceptibility i
Binding energy shifts between atomic and solid states have been observed with improved accuracy for All 4f and Ag 3d core levels applying a simultaneous measurement method. Also the 3d photoelectron spectrum and binding energies of free Ag atoms have been observed for the first time. New values determined as free atom to bulk solid shifts deviate considerably from previous estimate for Au but agre
Magnitude squared coherence (MSC) is a useful bivariate spectral measure that finds application in a wide variety of fields. In this paper, we develop a nonparametric Capon-based MSC estimator that utilizes a segmented reformulation of the recently introduced iterative adaptive approach (IAA) to provide high resolution MSC spectrum estimates. The proposed estimator, termed segmented-IAA-MSC (or SI
This article deals with the possibilities for Open Access (OA) publishing for Nordic researchers in law and in the humanities. Fifty-two journal editors answered a survey with questions on publishing in OA journals and on parallel publishing. The results show that the number of journals with a clear OA policy is low though a number of journals make articles freely available on the Internet without
A novel integrated approach to high-accuracy machining with industrial robots is presented in this paper. By combining a conventional industrial robot with an external compensation mechanism, a significantly higher bandwidth of the control of the relative position between the tool and the workpiece can be achieved. A model-based feedback controller for the compensation mechanism, as well as a mid-
Rationale and Objectives. The purposes of this study were to retrospectively identify various etiologies underlying intracranial hemorrhages (ICHs) in term infants aged <2 years and their respective prevalence in this population and to describe the long-term clinical outcomes in these patients. Materials and Methods. A retrospective review of the medical records and computed tomographic studies of
Aim and objectives. This article explores relatives' experiences of receiving soft tissue massage as a support supplement while caring for a dying family member at home. Background. In palliative home care, relatives play an important role as carers to seriously ill and dying family members. To improve their quality of life, different support strategies are of importance. Complementary methods, su
This paper investigates how Full-Scale Converter (FSC) wind turbines can contribute to voltage support in weak grids. A novel voltage support strategy is proposed, which optimizes the voltage support during the fault. This strategy is compared to the voltage support required by two grid codes, the Danish and the German E.ON ones. The influence of a number of parameters, as the network X/R ratio, t
The medieval western image of the Byzantine emperor Heraclius (c. 575-641) was largely formed by a Latin legend (BHL 4178) composed for the celebration of Exaltatio Crucis (14 Sept.). The main purpose of the article is to present a critical edition of this legend, together with an editio princeps of a Latin sermon (BHL 4181a) that tells the same story, as well as annotated English translations of
BACKGROUND: Primary cervical screening with both human papillomavirus (HPV) DNA testing and cytological examination of cervical cells with a Pap test (cytology) has been evaluated in randomized clinical trials. Because the vast majority of women with positive cytology are also HPV DNA positive, screening strategies that use HPV DNA testing as the primary screening test may be more effective. METHO
By studying law implementation in different areas and at different levels, contributors from various disciplines give a nuanced picture of law implementation in China, showing that it is rare to find examples of complete success or failure. Instead, making law work in actual practice, and in any society, is a matter of degree. The study is multidisciplinary in character and builds on insights from
It is not fully understood how much growth stresses affect the final quality of solid timber products in terms of, e.g. shape stability. It is, for example, difficult to predict the internal growth stress field within the tree stem. Growth stresses are progressively generated during the tree growth and they are highly influenced by climate, biologic and material-related factors. To increase the kn
Better estimates of the net exchange of CO(2) between the atmosphere and the terrestrial biosphere are urgently needed to improve predictions of future CO(2) levels in the atmosphere. The carbon cycle data assimilation system (CCDAS) offers the capability of inversion, while it is at the same time based on a process model that can be used independent of observational data. CCDAS allows the assimil
Björn Lindman has for fifty years had an active role in science and technology. His main contributions are briefly described. In the science part particular emphasis is put on his studies of ion binding, of amphiliphilc self-association, of molecular diffusion in solution and of polymer-surfactant systems. Furthermore we describe his role in introducing scientific areas, his role in scientific col
A study of a book dedicated to Gustavus II Adolphus. The author, the Dutch humanist and diplomat (in Swedish service) Jan Rutgers (Janus Rutgersius), takes as his point of departure the fact that GVSTAVVS is an anagramme for AVGVSTVS. This enables him to praise the Swedish king by referring to the Roman emperor as a model for a great monarch.
Using synchrotron based photoemission, we have investigated the Mn-induced changes in Ga 3d core level spectra from as-grown Ga(1-x)Mn(x)As. Although Mn is located in Ga substitutional sites, and therefore does not have any Ga nearest neighbors, the impact of Mn on the Ga core level spectra is pronounced even at Mn concentrations in the region of 0.5%. The analysis shows that each Mn atom affects
High-spin states in the doubly magic N=Z nucleus Ni-56 have been investigated with three fusion-evaporation reaction experiments. New gamma-ray transitions are added, and a confirmation of a previously suggested prompt proton decay from a rotational band in Ni-56 into the ground state of Co-55 is presented. The rotational bands in Ni-56 are discussed within the framework of cranked Nilsson-Strutin
Breast cancer treatment is based on tumor and patient related factors such as tumor stage, grade, hormonal status, HER2 status, patient age, and family history to name a few. It is today widely acknowledged that hypoxia and hypoxia-inducible factors (HIF:s) contribute to tumor progression. We therefore set out to explore the impact of hypoxia on mammary epithelial differentiation and what conseque
Recent in vitro studies have shown that the zymogen and activated form of factor (F)VII bind to endothelial cell protein C receptor (EPCR). At present, there is no evidence that FVIIa binds to EPCR on vascular endothelium in vivo in the presence of circulating protein C, a primary ligand for EPCR. The present study was carried out to investigate the interaction of murine and human ligands with mur
