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Blood vessels and adjacent cells form perivascular stem cell niches in adult tissues. In this perivascular niche, a stem cell with mesenchymal characteristics was recently identified in some adult somatic tissues. These cells are pericytes that line the microvasculature, express mesenchymal markers and differentiate into mesodermal lineages but might even have the capacity to generate tissue-speci
The efficacy of integrating open access geospatial data to produce habitat suitability maps for the corn bunting (Miliaria calandra) was investigated. Landsat Enhanced Thematic Mapper Plus (ETM+), Shuttle Radar Topography Mission (SRTM) and Corine (Coordination of Information on the Environment) land cover data for the year 2000 (CLC2000) were processed to extract explanatory variables and divided
The small flavoprotein NrdI is an essential component of the class Ib ribonucleotide reductase system in many bacteria. NrdI interacts with the class Ib radical generating protein NrdF. It is suggested to be involved in the rescue of inactivated diferric centres or generation of active dimanganese centres in NrdF. Although NrdI bears a superficial resemblance to flavodoxin, its redox properties ha
Diet and health during the Late Neolithic and Early Bronze Age Scandinavia have never been under systematic study. Still, high statures have been reported from osteologists, statures that indicate good health. This article is based on a pilot study examining health changes in relation to dietary changes due to intensified agriculture and the possible Secondary Products Revolution as discussed by S
BACKGROUND AND PURPOSE: Although there have been numerous publications on lumbar disc herniation (LDH) treated surgically, there has been little interest in sex differences. It has been shown in many studies that sex differences may be important in certain diseases. We therefore reviewed consecutive register material from one institution for possible gender differences in pre- and postoperative pa
Preparative chromatographic columns that run at high loads are highly sensitive to batch-to-batch disturbances of the process parameters, placing high demands on the strategy used for pooling of the product fractions. A new approach to pooling control is presented in a proof-of-concept study. A model-based sensitivity analysis was performed identifying the critical process parameters to product pu
The aim of the thesis is to discuss church building, the architectural design of Romanesque and Gothic churches and the use and symbolic interpretation of church buildings in the medieval period. It is suggested that churches were built for a variety of reasons, that the construction process may have been complicated and that the final result was not always the expected one. Many social groups wer
Our aim was to describe a large population-based cohort of diffuse large B-cell lymphoma (DLBCL) during the last decade, evaluating possible improvement in survival and to identify subgroups in need of novel treatment strategies. The study population encompassed all patients diagnosed with DLBCL in Sweden from 2000 through 2010. Altogether 5349 patients were identified. There was no increase in in
The relationship between Karl Pearson and the Scandinavian statisticians was more of a competitive than a collaborative nature. We describe the leading statisticians and stochasticists of the Scandinavian school, and relate some of their work to the work of Pearson.
Background-Retrospective studies have suggested that patients with a low transvalvular gradient in the presence of an aortic valve area <1.0 cm(2) and normal ejection fraction may represent a subgroup with an advanced stage of aortic valve disease, reduced stroke volume, and poor prognosis requiring early surgery. We therefore evaluated the outcome of patients with low-gradient "severe" stenosis (
Industrial robots are fast and accurate when working with known objects at precise locations in well-structured manufacturing environments, as done in the classical automation setting. In one sense, limited use of sensors leaves robots blind and numb, unaware of what is happening in their surroundings. Whereas equipping a system with sensors has the potential to add new functionality and increase
Travel in the footsteps of cinema is an expanding market, both in Sweden and internationally. Travel habits are changing, and the fact of a good number of people planning their journeys in order to follow in the footsteps of fictitiousn characters, or alternatively follow a particular route in order to experience first-hand something they saw at the cinema or on television, has become an important
This paper is the state of the art of charcoal signal studies (macro-, meso- and micro-charcoal) that have been carried out at the Epigravettian settlement of Mezhyrich. This work took part of the French ANR project "Mammouths". Charcoal signals have been found in both natural and archaeological (pits and activity areas) deposits that have been sampled during the 2007-2008 archaeological excavatio
It is often suggested that aesthetic and ethical value judgements are similar in such a way that they should be analysed in analogous manners. In this paper, I argue that the two types of judgements share four important, features concerning disagreement, motivation, categoricity, and argumentation. This, I maintain, helps to explain why many philosophers have thought that aesthetic and ethical val
Abstract in UndeterminedThe dominant explanation for China's unprecendented rates of economic growth in the last three decades has regarded them as the consequence of the reform policies that, after Mao, the Chinese leaders embarked upon in 1978. The present study, in contrast, argues for continuity between the socialist period and the post-refrom era in China's economic course.Chinse socialism, i
Neuroblastoma patients show remarkable clinical heterogeneity, with courses ranging from spontaneous regression to fatal tumor progression despite intense multi-modal treatment. Previous studies have shown that hypoxia pushes neuroblastoma cells towards a more immature phenotype, which correlates to aggressive disease. Here we define a role for the hypoxia inducible factor-2α in neuroblastoma tu
This thesis adds to the knowledge base of how the Individual Placement and Support (IPS) can be optimized to secure a more sustainable working career for people with severe mental illness (SMI). The thesis has given the IPS-participants an active voice about what it is like to start to work in a Swedish context, visualised the psychiatric disability in relation to work, discerned the support and p
We calculated average aquatic dissolved organic carbon (DOC) age (the time span from soil discharge to observation) in water from the inlets and outlets of two unproductive Swedish lakes at different times during an annual cycle. Bacterial production (BP) and bacterial growth efficiency (BGE) determined during 7-d bioassays decreased with increasing average aquatic DOC age. Parallel to the decline
