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BACKGROUND/OBJECTIVES: Heavy alcohol drinking is a risk factor of colorectal cancer (CRC), but little is known on the effect of polymorphisms in the alcohol-metabolizing enzymes, alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) on the alcohol-related risk of CRC in Caucasian populations. SUBJECTS/METHODS: A nested case-control study (1269 cases matched to 2107controls by sex, age, stu

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Intracellular membrane fusion is coordinated by membrane-anchored fusion proteins. The cytosolic domains of these proteins form a specific complex that pulls the membranes into close proximity. Although some results indicate that membrane merger can be accomplished solely on the basis of proximity, others emphasize the importance of bilayer stress exerted by transmembrane peptides. In a reductioni

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Suicide is a major global health problem imposing a considerable burden on populations in terms of disability-adjusted life years. There has been an increasing trend in fatal and attempted suicide in Iran over the past few decades. The aim of the current study was to assess overall, gender and social inequalities across Iran's provinces during 2006-2010.

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Recension av Barbro Eberan, Förlorade generationer? Tyskarna och skuldfrågan.

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The effects induced by Na deposited on furnace grown graphene on SiC(0001) and after subsequent annealing are investigated using LEEM, mu-LEED, mu-PES and XPEEM. Intercalation in between carbon layers and at the interface is observed to occur both on the 1 ML and 2 ML areas directly after Na deposition. Annealing at a temperature around 100 degrees C is found to strongly promote Na intercalation.

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In this paper a count data regression model accounting for endogenous censoring with household specific censoring thresholds is presented. The presented modelling approach is utilized in an analysis of household choice of total number of nights to spend on monthly recreational trips. The empirical study reveals that the suggested approach is feasible and that accounting for endogenous censoring gi

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Melangyna pavlovskyi (Violovitsh, 1956) has been found breeding in Denmark. The species is recorded from four localities on Zealand, and it is established on at least one of these. It is new to the European fauna. A redescription of M. pavlovskyi based on the external characters and an updated key to the NW European species of Melangyna are presented.

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Background and purpose The Hansson Twin Hook (HTH) is an alternative to the lag screw in the treatment of trochanteric fractures. In osteoporotic bone, mechanical tests have indicated that the HTH has better fixation properties than the lag screw. We evaluated the fixation stability of the HTH in a large series of elderly patients with trochanteric fractures. Many surgeons were involved in assessm

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We consider the following signaling game. Nature plays first from the set {1,2}{1,2}. Player 1 (the Sender) sees this and plays from the set {A,B}{A,B}. Player 2 (the Receiver) sees only Player 1’s play and plays from the set {1,2}{1,2}. Both players win if Player 2’s play equals Nature’s play and lose otherwise. Players are told whether they have won or lost, and the game is repeated. An urn sche

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This paper presents a novel online approach of merging multiple different predictors of time-varying dynamics into a single optimized prediction. Different predictors are merged by recursive weighting into a single prediction using regularized optimization. The approach is evaluated on two different cases of data with shifting dynamics; one example of prediction using several approximate models of

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The purpose of this study is to investigate how people express religious and national identities in the conflict-ridden Patani region of southern Thailand. In a historical framework of disputes over territory and political legitimacy, where identities have developed in response to an emerging Thai nation, it is of relevance to understand the dynamics of these identities and to disclose how local p

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We report on the production of inclusive gamma(1S) and gamma(2S) in p-Pb collisions at root S-NN = 5.02 TeV at the LHC. The measurement is performed with the ALICE detector at backward (-4.46 < ycms < 2.96) and forward (2.03 < ycms <3.53) rapidity down to zero transverse momentum. The production cross sections of the gamma(1S) and gamma(2S) are presented, as well as the nuclear modification factor

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Postural control is the ability to maintain equilibrium and orientation in a gravitational environment. It is dependent on feedback and feedforward mechanisms that generate appropriate corrective movement based on body-sway motion detected primarily by visual, vestibular, and proprioceptive sensory systems. Since information from the various senses is not always accurate (e.g. by disease) or avail

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Biological invasions might constitute a major threat to mutualisms. Introduced pollinators might competitively displace their native counterparts, which in turn affects the pollination of native plants, if native and alien visitors differ in pollinator effectiveness. Since its invasion in 1994 into south-west Argentina, the introduced European bumblebee Bombus ruderatus has continuously increased

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BACKGROUND AND PURPOSE: The etiology of subarachnoid hemorrhage (SAH) is poorly understood. Reduced lung function, expressed as low forced expiratory volume in 1 second (FEV(1)) and low forced vital capacity (FVC), is a predictor of cardiovascular disease, but whether reduced lung function is a risk factor for SAH is not known. The association between lung function and incidence of SAH was invest

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Practical aspects of light-duty diesel combustion system design are reviewed, with an emphasis on design considerations reported by manufacturers and engine design consultancies. The factors driving the selection of compression ratio, stroke-to-bore ratio, and various aspects of combustion chamber geometry are examined, along with the trends observed in these parameters in recently released engine

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Popular Abstract in Swedish De två vanligaste typerna av neurodegenerativ demenssjukdom är Alzheimer’s sjukdom och Lewy body demens. Båda sjukdomarna drabbar framförallt äldre människor och risken att insjukna ökar med stigande ålder. Detta innebär att demenssjukdom kommer att bli vanligare i samhället, eftersom vi blir allt äldre och andelen invånare >65 år blir allt större. Att drabbas av demensBackground: A prognostic marker should provide information about course and outcome of disease, e.g. predict time to a given endpoint or rate of progression due to disease in patients or subgroups of patients. Prognostic markers could be targeted to apply during the entire clinical course or just during distinct stages of the disease. Aim: The aim of this thesis is to identify, review and qualif

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Aims: We tested whether autoantibodies to all three ZnT8RWQ variants, GAD65, insulinoma-associated protein 2 (IA-2), insulin and autoantibodies to islet cell cytoplasm (ICA) in combination with human leukocyte antigen (HLA) would improve the diagnostic sensitivity of childhood type 1 diabetes by detecting the children who otherwise would have been autoantibody-negative. Methods: A total of 686 pat