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Telomere repeat amplification protocol (TRAP in situ reveals telomerase activity in three cell types in effusions: malignant cells, proliferative mesothelial cells, and lymphocytes

Telomerase Repeat Amplification Protocol (TRAP) in situ was performed on cytospin preparations from 65 effusions from the serous cavities (45 pleural and 19 ascitic fluids and one pericardial fluid) submitted for routine diagnosis and the results were correlated to cytological morphology. Three types of cells with nuclear fluorescence were identified: malignant cells, hyperplastic mesothelial cell

PIXE Detection Limits for some Aerosol Collection Substrates by Excitation with protons and 4He2+ Ions from a 3 MV Tandem Accelerator

Comparisons of PIXE detection limits for K, X rays using 2-5 MeV protons and 7-8 MeV 4He2+ ions as projectiles have been performed. The comparisons have been made for common aerosol backings. According to simple theoretical considerations regarding X-ray production cross sections and the production of background radiation, detection limits for 4He2+ should be two to four times lower than for proto

Regulation of lipoprotein lipase. Induction by insulin

Lipoprotein lipase activity in intact epididymal adipose tissue of fasted rats increased rapidly after treatment with insulin in vivo. In contrast, lipoprotein lipase activity in adipocytes isolated from the contralateral fat pads remained essentially unchanged. When adipocytes were incubated for 30 min at ambient temperature in vitro, about 2 times more lipoprotein lipase activity was found in th

Polybrominated diphenyl ethers in precipitation in Southern Sweden (Skane, Lund)

The presence of polybrominated diphenyl ether (PBDE) flame retardants in total deposition (wet + dry) was assessed with the simultaneous use of three bulk samplers during a 2 week period. The particle associated and the 'dissolved' phase were separated during sampling. Volume weighted mean (VWM) concentrations of SigmaPBDE (9 congeners) in rain were 209 pg l(-1). Total deposition rates were 2 +/-

Extended object wavefront sensing based on the correlation spectrum phase

In this paper we investigate the performance of a Fourier based algorithm for fast subpixel shift determination of two mutually shifted images subjected to noise. The algorithm will be used for Shack-Hartmann based adaptive optics correction of images of an extended object subjected to dynamical atmospheric fluctuations. The performance of the algorithm is investigated both analytically and by Mon

Eating difficulties in elderly, focusing on patients with stroke.

Popular Abstract in Swedish För att ge en god omvårdnad behövs kunskaper om ätproblem som helhet och om möjliga hinder för optimalt näringsintag hos äldre patienter, särskilt de med stroke. Sådana kunskaper behövs eftersom åldrandet i sig självt eller tillsammans med sjukdom, t.ex. stroke och dess följder, kan påverka förmågan att äta och därmed också näringsintaget med ökad risk för såväl undernäThe aim of this thesis was to describe eating difficulties and interventions to improve eating among elderly patients, especially those with stroke, to make comparisons between patients with dysphagia and those without (Papers I & II), those with and without assisted eating (Paper IV), and to analyse the relation between eating difficulties, nutritional status (Papers II-V), pressure ulcers (P

The dysmetabolic syndrome

The first unifying definition for the metabolic syndrome was proposed by WHO in 1998. In accordance to this, patients with type 2 diabetes mellitus or impaired glucose tolerance have the syndrome if they fulfil two of the criteria: hypertension, dyslipidaemia, obesity/abdominal obesity and microalbuminuria. Persons with normal glucose tolerance (NGT) should also be insulin resistant. About 40% of

The predictive value of microbiologic diagnostic tests if asymptomatic carriers are present

If a proper gold standard is not available, then the predictive value of a test cannot be estimated. In this paper the concept of etiologic predictive value (EPV) is introduced. It is a quantity that will yield the predictive value of a test to predict presence of a specified disease in situations for which no proper gold standard is available. This is achieved by using information obtained from a

Ärftlighetsforskningens gränser : Individer och institutioner i framväxten av svensk genetik

Popular Abstract in Swedish Den moderna genetiken tar sin början kring sekelskiftet 1900 då de mendelska lagarna återupptäcktes. Den tidiga utvecklingen skedde i många länder i nära anslutning till den praktiska växtförädlingen, så även i Sverige där det redan fanns en framgångsrik växtförädling genom Sveriges utsädesförenings verksamhet i Svalöf. Här introducerade botanisten Herman Nilsson-Ehle mIn the first part of the 20th century genetics developed into an important research field. The aim of this study is to follow and analyse the transformation of genetics from its origin within an agricultural context to an academic discipline in Sweden (ca. 1900-1960). Mendelism was introduced as a methodology in plant breeding at the plant breeding station in Svalöf during the first decade of the

Pancreatitis-Associated Pulmonary Injury

Popular Abstract in Swedish Akut bukspottkörtelinflammation (akut pankreatit ? AP) är en akut inflammation som kan resultera i en självdestruktiv process i bukspottkörteln. 70-80 % av fall med AP klassificeras som lätta-måttliga och är självbegränsande, medan cirka 20 % klassas som svåra och karakteriseras av utvecklingen av nekros (vävnadsdöd) i bukspottkörteln och omkringliggande vävnad, utvecklIn acute pancreatitis (AP), lung injury is an early occuring and important part of the multiple organ dysfunction syndrome. The mechanisms underlying the development of lung injury though still largely remains unclear. The aim of the present study was to study mechanisms of the systemic and secondary pulmonary inflammation and injury, with an emphasis on the involvement of immune cells, inflammato

Solving large scale binary quadratic problems: Spectral methods vs. Semidefinite programming

In this paper we introduce two new methods for solving binary quadratic problems. While spectral relaxation methods have been the workhorse subroutine for a wide variety of computer vision problems - segmentation, clustering, image restoration to name a few - it has recently been challenged by semidefinite programming (SDP) relaxations. In fact, it can be shown that SDP relaxations produce better

Atrial fibrillation--Where do we stand today?

The basic underlying mechanisms behind atrial fibrillation (AF), the most abundant therapy demanding cardiac dysrhythmia, have until recently being largely unknown. Once established, AF is not only self-perpetuating but also self-destructive, prompting rapid treatment against possible initiating mechanisms. Recent observations reveal that the ectopic beats, initiating AF, often originate in the wa

Transient wave propagation in reciprocal bi-isotropic media at oblique incidence

In this paper a new wave splitting is suggested that simplifies the analysis of wave propagation in reciprocal bi-isotropic media. Two different methods to solve the scattering problem are analyzed: the invariant imbedding and the Green function approach. The medium is modeled by constitutive relations in the time domain (time convolutions) and the slab is assumed to be inhomogeneous with respect