The respiratory pathogen Moraxella catarrhalis is a human-specific commensal that frequently causes acute otitis media in children and stimulates acute exacerbations in chronic obstructive pulmonary disease patients. The exact molecular mechanisms defining host-pathogen interactions promoting pathogenesis are not clearly understood. Limited knowledge hampers vaccine and immunotherapeutic developme

Islet autoantibodies (IAs) precede the clinical onset of type 1 diabetes (T1D); however, the knowledge is limited about whether the prodrome affects complete blood counts (CBCs) in 4- to 12-year-old children with increased genetic risk for T1D. This study tested whether CBCs were altered in 4- to 12-year-old children without (n = 376) or with one or several IAs against insulin, GAD65, or IA-2 (n =

Objective: To study the impact of common noncomposite disease activity measures on sick leave in biologics-treated patients with rheumatoid arthritis (RA). Methods: Data from study visits by biologics-treated RA patients of working age (

Swedish nursing homes' use of Instagram has increased vastly in the past few years. Instagram is understood as a means to manage the image they wish to mediate to the public. This article examines what is displayed in the nursing homes' Instagram accounts, and what kind of reality is thereby constructed. The data consist of 338 Instagram images from four nursing homes' Instagram accounts. It is fo

Intensive agricultural management negatively affects both natural enemies of pests and pollinators. Such management also has the potential to adversely affect the ecosystem services that these communities confer. Organic management has been proposed as an alternative method to mitigate such problems by restoring the services provided by arthropod communities. We evaluated the effect of organic man

The requirements on high efficiency and low emissions of internal combustion engines (ICEs) raise the research focus on advanced combustion concepts, e.g., premixed-charge compression ignition (PCCI), partially premixed compression ignition (PPCI), reactivity controlled compression ignition (RCCI), partially premixed combustion (PPC), gasoline compression ignition (GCI) etc. In the present study,

Scope: Several dietary fiber properties are suggested to be important for the profiling of the microbiota composition, but those characteristics are rather unclear. Whether different physico-chemical properties of barley dietary fiber influence the gut microbiota composition is investigated. Methods and results: Seven diets containing equal amounts of dietary fiber from barley malts, brewer's spen

In this paper we consider a mobile platform with two cameras directed towards the floor mounted the same distance from the ground, assuming planar motion and constant internal parameters. Earlier work related to this specific problem geometry has been carried out for monocular systems, and the main contribution of this paper is the generalization to a binocular system and the recovery of the relat

During the biosynthesis of chondroitin/dermatan sulfate (CS/ DS), a variable fraction of glucuronic acid is converted to iduronic acid through the activities of two epimerases, dermatan sulfate epimerases 1 (DS-epi1) and 2 (DS-epi2). Previous in vitro studies indicated that without association with other enzymes, DS-epi1 activity produces structures that have only a few adjacent iduronic acid unit

Extracellular histones are present in the airways because of cell death occurring during inflammation. They promote inflammation and cause tissue damage due to their cationic nature. The anionic phosphoglycoprotein osteopontin (OPN) is expressed at high levels during airway inflammation and has been ascribed both pro- and anti-inflammatory roles. In this study, it was hypothesized that OPN may neu

Background: Data suggests that the plasma levels of the liver-specific miR-122-5p might both be a marker of cardiogenic shock and a prognostic marker of out-of-hospital cardiac arrest (OHCA). Our aim was to characterize plasma miR-122-5p at admission after OHCA and to assess the association between miR-122-5p and relevant clinical factors such all-cause mortality and shock at admission after OHCA.

Historia i futurum handlar på ett övergripande plan om synen på historieämnet i svensk skola från 1919 till 2011 såsom det kommer till uttryck i styrdokument och lärobokstexter. Den är också en av de första studierna av hur kunskapsutveckling i historia kan uttryckas teoretiskt och hur sådana tankegångar har tillämpats – eller inte tillämpats – på grundskolans och gymnasiets historieämne. I princiFacing an unknown future, the meaning of history is not primarily a fixed set of knowledge about the past, but a well-developed historical consciousness. This is a generic skill, emanating from an understanding of history as something that we are, and at the same time as something that we create. From a historical-cultural perspective, the learning process can be described with a point of departur