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The growing challenge of antibiotic resistance calls for alternative therapeutic strategies beyond conventional antibiotics. Antibacterial Photodynamic Therapy (aPDT), based on the light-induced generation of Reactive Oxygen Species (ROS), offers a non-specific approach that is detrimental to bacterial cells at multiple levels. Here, we explore the photocatalytic properties of nitrogen-doped titan
Oats (Avena sativa L.) are gaining increased attention for their rich dietary fibres, proteins and bioactive compounds. Among fibres, starch components denoted as resistant starch (RS) contribute significantly to the functional and nutritional properties of oat-based foods. This study presents the optimization of a high-throughput quantification method for amylose, a key structural component that
Urbanisation, digitalisation and emerging technologies are reshaping young people’s relationship with the outdoor environment. We investigate how everyday outdoor experiences and spaces support adolescent wellbeing, understood as both feeling good and functioning well. Adolescents, at a pivotal stage in life, are particularly sensitive to environmental factors that influence their wellbeing. We co
Bacillus thuringiensis (Bt) strains naturally produce pesticidal proteins as nanocrystalline inclusions that are extraordinarily stable in aqueous environments, but which dissolve selectively at specific pH conditions. These proteins have been used in agriculture for >50 years and are critical to global food security. The majority of previously determined Bt Cry protein structures lack the extende
Atmospheric vapor pressure deficit (VPD) is a key climatic factor that influences vegetation productivity and the global carbon cycle. With ongoing climate warming, VPD has been rising globally. However, the effects of this increase on gross primary production (GPP), especially under different driving mechanisms, remain unclear. This uncertainty limits our ability to predict terrestrial ecosystem
Neuroinflammation emerges as a central driver of neurodegeneration, yet the molecular regulators orchestrating pathological microglial activation remain incompletely understood. This thesis investigates galectin-3 (Gal3), a glycan-binding protein with dual roles in microglial homeostasis and inflammatory signaling, as a master regulator linking neuroinflammation to proteinopathy progression in Alz
Studio recordings of music for English bass horn and string trio from the composers Louis Massonneau, Emma Jane Lloyd, and Ylva Lund Bergner, recorded at the St Cecilia's Hall in Edinburgh on 17 January 2026.
Background The dura mater has a permeable vasculature similar to that of peripheral organs, and is separated from the brain, which is enclosed within the arachnoid barrier. Fluid and solute transport across the arachnoid barrier between the subarachnoid space (SAS) and dura is crucial for brain waste clearance and immune surveillance, but few neuroimaging approaches can capture this dynamic proces
The ability to hold listeners’ attention and prevent habituation is a crucial design feature for both biological and human-made distress and alarm signals, but their intrusive nature also causes stress and annoyance. To investigate what makes vocalizations distracting and annoying, we developed Self-Steered Sound Synthesis—a new experimental paradigm for studying voice perception, in which untrain
ObjectivesPeople with serious illness approaching end of life often end up in emergency and hospital care, frequently against expressed preferences. Consequently, oncology trials record care days as a measure of treatment burden called “time toxicity.” However, this measure ignores the diminishing marginal utility of time: that the value of a day is higher when fewer remain. We aimed to incorporat
The study investigates how the Best Interests of the Child principle in the UN Children's Rights Convention (Article 3) has been adapted in custody disputes in Egypt, Sweden, and Uzbekistan. Although the Convention on the Rights of the Child offers a common normative benchmark, divergent legal cultures shape its domestic meaning: Egypt is governed by religious and state legal norms intersecting wi
European forests have served as a critical carbon sink, absorbing approximately 10% of annual anthropogenic CO₂ emissions in the EU, as a result of both increased forest area and growing stock since 1950. However, this sink has declined by one-third over the past decade, based on the EU National Greenhouse Gas Inventory. This decline has been proposed to be due to multiple interacting factors: cli
Bedömning av ett barns talsvårigheter behöver baseras på flera uppgifter och testmetoder för att möjliggöra identifiering av den eller de talproduktionsnivåer som är inblandade. Syftet med studien var att undersöka hur ett benämningstest och ett dynamiskt motoriskt taltest bidrog till observationer av talbeteenden förenliga med brister i talmotorisk planering. Deltagarna var 28 barn mellan tre ochThe assessment of a child’s speech problem should incorporate several tasks and sampling methods to identify the difficulties appointing the speech production level/s involved. This study aimed to investigate how a dynamic motor speech test contributed to a naming test in observing speech characteristics consistent with deficits of speech motor planning. Participants were 28 children, 3 to 9 years
Wood density is a crucial anatomical trait influencing forest carbon storage. However, dynamic global vegetation models (DGVMs) typically assume a fixed species-level wood density, neglecting environment-driven variability. In this proof-of-concept study, we explore the potential impact of dynamic wood density on tree- and forest-level carbon storage by integrating a simple temperature-response fu
BackgroundIntravenous immunoglobulins (IVIG) have been suggested as an adjunctive treatment in streptococcal toxic shock syndrome (STSS), but there are no conclusive trials. In southern Sweden, IVIG is routinely used in certain hospitals but not in others. We hypothesized that this would resemble a natural experiment, and aimed to evaluate the effect of IVIG in STSS patients.MethodWe conducted a p
Patients with pulmonary arterial hypertension (PAH) experience long diagnostic delays, high functional class at diagnosis and poor prognosis. We aimed to study the differentiative and predictive value of 90 inflammatory and immunomodulatory related proteins in idiopathic and hereditary PAH (IPAH/HPAH) and systemic sclerosis-associated PAH (SSc-APAH). Cohort 1 comprised patients with SSc-APAH ( n
