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Background: Club cell secretory protein (CC16) probably has a role in protecting the lung from inflammation. Aim: To evaluate if low levels of CC16 in gastric fluid at birth, reflecting low levels of CC16 in the lung, would be associated with lung inflammation and respiratory morbidity. Methods: A study of 64 infants with mean gestational age 26.1 weeks. CC16 was analyzed in gastric fluid at birth
Amyloid protein aggregation results in major disturbances of cellular processes in humans. The most common amyloid-related disorders are Alzheimer´s disease and Parkinson´s disease. Parkinson´s disease is charaterized by the formation of protein-rich aggregates that are deposited in neurons, termed Lewy bodies and Lewy neurites. The main component identified in these protein-rich deposits is the pAmyloid protein aggregation results in major disturbances of cellular processes in humans. The most common amyloid-related disorders are Alzheimer´s disease and Parkinson´s disease. Parkinson´s disease is charaterized by the formation of protein-rich aggregates that are deposited in neurons, termed Lewy bodies and Lewy neurites. The main component identified in these protein-rich deposits is the p
Current research on enzyme based electrochemical biosensors deals essentially with the same target analytes as was at focus in the early days of biosensor research, that is those within the clinical/medical, food/agriculture, and environmental fields [1•–13]. However, there has been substantial progress through the years and progress continues, as resumed in Figure 1A. One of the major differences
This study investigated the links between students' behavioral problems, student–teacher conflict, and students' involvement in bully, victim, and bully/victim roles in adolescence. The role of student–teacher conflict as moderator of the association between students' behavioral problems and their involvement in each bullying role was examined. Sample included 430 students from Italy (48.4% female
Ecological intensification provides opportunity to increase agricultural productivity while minimizing negative environmental impacts, by supporting ecosystem services such as crop pollination and biological pest control. For this we need to develop targeted management solutions that provide critical resources to service-providing organisms at the right time and place. We tested whether annual str
Objective:The aim of this study was to investigate and compare the prevalence and recurrence of police interaction (PI) with patients diagnosed with dementia. We also aimed to study the reason behind the PI, the time of occurrence of PI, and potential consequences of the PI.Methods:For this retrospective medical records’ review, we included 281 cases with a neuropathologic dementia diagnosis from
We present charged-particle distributions sensitive to the underlying event, measured by the ATLAS detector in proton-proton collisions at a centre-of-mass energy of 13 TeV, in low-luminosity Large Hadron Collider fills corresponding to an integrated luminosity of 1.6 nb−1. The distributions were constructed using charged particles with absolute pseudorapidity less than 2.5 and with transverse mom
A search is presented for anomalous quartic gauge boson couplings in vector-boson scattering. The data for the analysis correspond to 20.2 fb-1 of s=8 TeV pp collisions and were collected in 1972 by the ATLAS experiment at the Large Hadron Collider. The search looks for the production of WW or WZ boson pairs accompanied by a high-mass dijet system, with one W decaying leptonically and a W or Z dec
Differential cross sections are presented for the prompt and non-prompt production of the hidden-charm states X(3872) and ψ(2S), in the decay mode J/ψπ+π−, measured using 11.4 fb−1 of pp collisions at s=8 TeV by the ATLAS detector at the LHC. The ratio of cross-sections X(3872)/ψ(2S) is also given, separately for prompt and non-prompt components, as well as the non-prompt fractions of X(3872) and
We perform hydrodynamic simulations of mass transfer in binaries that contain a white dwarf and a neutron star (WD-NS binaries), and measure the specific angular momentum of material lost from the binary in disc winds. By incorporating our results within a long-term evolution model, we measure the long-term stability of mass transfer in these binaries. We find that only binaries containing helium
Measurements of dijet pT correlations in Pb+Pb and pp collisions at a nucleon–nucleon centre-of-mass energy of sNN=2.76 TeV are presented. The measurements are performed with the ATLAS detector at the Large Hadron Collider using Pb+Pb and pp data samples corresponding to integrated luminosities of 0.14 nb−1 and 4.0 pb−1, respectively. Jets are reconstructed using the anti-kt algorithm with radius
Background: Bisphosphonates have previously been shown to increase the density of impacted graft bone. In the present study we hypothesise that bisphosphonates also reduce early stem subsidence. We examined the effect of locally applied bisphosphonate to allografts on prosthetic micromotion and bone density in femoral stem revision with impaction grafting. Methods: 37 patients were randomised to e
Objective: Atherosclerosis is characterized by accumulation of lipids, cells and extracellular matrix (ECM) proteins in the arterial wall. Collagen type I (COL1), a component of the arterial ECM, is cleaved by matrix metalloproteinases (MMPs) and known to be remodelled in atherosclerosis. We explored whether the MMP-mediated COL1 biomarker, C1M, was associated with cardiovascular events, cardiovas
The semi-quantitative estimate standardised uptake value ratios (SUVR) correlate well with specific binding of the tracer expressed as distribution volume ratios (DVR) for the tau positron emission tomography tracer [18F]AV-1451 uptake and are therefore widely used as proxy for tracer binding. With regard to tracer kinetic modelling, there exists a time point when SUVR deviates minimally from DVR,
U–Pb zircon dates of metagabbroic rocks, such as eclogite, mafic granulite, and garnet amphibolite, are used to constrain the timing of tectonometamorphic evolution in orogens worldwide. For such interpretation, however, it is imperative to define at which stage of the P–T evolution that zircon crystallization took place: the prograde, peak, or retrograde stage. In order to accurately interpret me
We consider Hilbert spaces of analytic functions in the disk with a normalized reproducing kernel and such that the backward shift f(z)↦[Formula presented] is a contraction on the space. We present a model for this operator and use it to prove the surprising result that functions which extend continuously to the closure of the disk are dense in the space. This has several applications, for example
