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We propose that impaired complement function enhances a pathogenetic vicious circle in SLE. In this process, induction and clearance of apoptotic cells is central. Apoptosis could be triggered by various etiological factors, such as infection, UV light, and drug reactions. Clearance of apoptotic material is reduced when complement function is impaired. Apoptosis leads to increased exposure of nucl

Objective. To investigate antibody responses to a broad panel of peptides derived from human endogenous retroviruses (HERVs) among unselected patients with systemic lupus erythematosus (SLE). Methods. In sera obtained from 69 patients with SLE and healthy blood donors, immunoassay was used to measure levels of antibody against synthetic peptides derived from HERVs, exogenous retroviruses, and nonv

Datalog has emerged as a powerful tool for expressing staticprogram analyses. Program analysis researchers have builtnontrivial code bases in Datalog, but tool support for workingwith Datalog itself has been lacking. In this paper, weintroduce MetaDL, a language extension to Datalog thatenables source-level Datalog program analysis within Datalog.We describe several program analyses implemented in

BACKGROUND: Current guidelines recommend that comatose out-of-hospital cardiac arrest patients with ST-segment elevations (STEs) following return of spontaneous circulation (ROSC) should be referred for an acute coronary angiography. We sought to investigate the diagnostic value of the pre-hospital ROSC-ECG in predicting ST-elevation myocardial infarction (STEMI).METHOD: ROSC-ECGs of 145 comatose

Aims Among patients with acute coronary syndromes (ACS), those with diabetes mellitus (DM) are at particularly high risk of recurrent cardiovascular events and premature death. We aimed to provide a descriptive overview of unadjusted analyses of patient characteristics, ACS management, and outcomes up to 1 year after hospital admission for an ACS/index-ACS event, in patients with DM in contemporar

The use of interactive visualization techniques in Digital Humanities research can be a useful addition when traditional automated machine learning techniques face difficulties, as is often the case with the exploration of large volumes of dynamic—and in many cases, noisy and conflicting—textual data from social media. Recently, the field of stance analysis has been moving from a predominantly bin

Tio skandinaviska forskare med livslång erfarenhet av studier och forskning om Indien har skrivit originalartiklar kring sina specialområden såsom ekonomi, politik, kvinnofrågor, sociala förhållanden, kultur och religion. Boken söker sig under ytan av gängse Indienbilder och försöker förstå det moderna Indien i ett historiskt perspektiv som en del av en dynamik där också framtiden avtecknar sig.

Indiens historia ur ett samhällsvetenskapligt perspektiv

Landsbygdens förändring under de senaste femtio åren. Grön revolution och mekanisering av jordbruket. Arbetsmigration till städerna. Kasternas frigörelse. Regional politik.

Miljön hotas av förgiftning av luft, vatten och jordar. Industriutveckling och gruvdrift förstör miljön, liksom användningen av kol och bensin i de ständigt ökande transporter. Indiens möjligheter att komma till rätta med detta.

In 2005 a Greek and American interdisciplinary team investigated two shipwrecks off the coast of Chios dating to the 4th-century b.c. and the 2nd/1st century. The project pioneered archaeological methods of precision acoustic, digital image, and chemical survey using an autonomous underwater vehicle (AUV) and in-situ sensors, increasing the speed of data acquisition while decreasing costs. The AUV

To investigate why people live in areas at high risk of floods, a qualitative case study was carried out in the areas around Akuressa, in southwest Sri Lanka. Data col- lection consisted mainly of semistructured interviews with local residents and government officials. The purpose was to study why people live in areas at high risk of floods, by looking beyond the purely physical aspects of living

Floods tend not to be bounded by geopolitical or administrative borders, and involve various sectors in society. Flood risk must thus be jointly governed by a web of actors (Renn, 2008), who are not independent of each other but dependent on various resources and affected by the decisions and actions others are making (Becker, 2014). The patterns of social relations among these actors are therefor

Urban flood risk is a big and growing concern in Sweden. Although much focus is placed on rainfall, hydrology, and engineering conceptualizations of both consequences and solutions, social research contributes to explaining and understanding risk and how actors perceive, construct, and manage it together. This paper applies social network analysis to investigate the network of actors in Höje river

C.W. Mills suggests that having sociological imagination entails having ability to both distinguish between and connect personal troubles and public issues. This has been a guiding principle for much sociology in the last fifty years, but is never simple and continues to challenge the discipline. Especially the increasing number of sociologists engaging in endeavours to explain, understand, and im

Adaptation is regarded as a panacea among policy circles. This paper offers a somewhat different perspective, using life narratives to investigate the conflictual nature of adaptation in and around vulnerable communities in Nepal and Maldives. Our analysis results in a framework with three dimensions: (1) qualitative differences in type of conflict; (2) the relative positions of the conflicting ac