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Performing research at university centers for academic development – an explorative case study in Sweden

The aim is to explore the absence or presence of, and motives for, research at centers for academic development and to problematize the research situation among academic developers. Boyer’s and Healey’s theories are used as lenses for the analysis based on the questionnaires that were used for data collection. The conclusion is that research is a challenging and sensitive area for university cente

Perceptions of Volunteerism by Young People of Macau and How this has influenced the Market Performance of the Non-Profits

This study investigated the perceptions of the young citizens of Macau about volunteerism, and how this perception affected volunteer reruitment and retention, and the market strategies of the non-profits. The study covered implicitly the question of competition and substitution of volutneerism as perceived by the young people in Macau; how the non-profits competed with each other in recruiting vo

Sustainable insulation of historical wooden and stone buildings with lime-hemp

In this multidisciplinary project lime-hemp is studied as a thermal insulating material for the renovation of historic timber and brick buildings*). Focus is on buildings in the historic city of Visby on the Swedish island of Gotland in the Baltic sea. Many historic buildings in Visby have over the past decades been thermally insulated with materials such as mineral wools and polystyrene. Due to t

Centrality dependence of ψ(2S) suppression in p-Pb collisions at √sNN= 5.02 TeV

The inclusive production of the ψ(2S) charmonium state was studied as a function of centrality in p-Pb collisions at the nucleon-nucleon center of mass energy √sNN = 5.02 TeV at the CERN LHC. The measurement was performed with the ALICE detector in the center of mass rapidity ranges −4.46 < ycms< −2.96 and 2.03 < ycms< 3.53, down to zero transverse momentum, by reconstructing the ψ(2S) decay to a

Human cervical ripening, an inflammatory process mediated by cytokines

An extensive remodelling process, referred to as cervical ripening, takes place in the cervical tissue during pregnancy and labour. It is recognized as softening and dilation of the cervical canal, and starts as a slow process during pregnancy, becoming rapid close to partum. In this study we focus on cytokines as possible mediators of this final remodelling. mRNA levels for interleukin (IL)-8, IL

TGF-beta enhances the production of hyaluronan in human lung but not in skin fibroblasts

Transforming growth factor-beta (TGF-beta) enhances the production of extracellular matrix components, such as type I and type III collagen, fibronectin, proteoglycans, in various cell types. The effect on hyaluronan synthesis in relation to proteoglycan synthesis has not been investigated. Human lung or skin fibroblast cultures were treated with TGF-beta in serum-free medium for various periods o

Diet of generalist predators reflects effects of cropping period and farming system on extra- and intraguild prey

The suppression of agricultural pests by natural enemies, including generalist arthropod predators, is an economically important regulating ecosystem service. Besides pests, generalist predators may also consume non-pest extraguild and intraguild prey, which can affect their impact on pest populations. This may either reduce the impact of generalist predators on pest populations, because they are

Heparan sulfate upregulates platelet-derived growth factor receptors on human lung fibroblasts

Heparan sulfate is a molecule that possesses a large structural variability and which has been shown to inhibit the proliferation of fibroblasts in vitro. The aim of this study was to determine whether the anti-proliferative effects of heparan sulfate were exerted by regulation of the activity of the platelet-derived growth factor and/or of the platelet-derived growth factor receptors. Both l-idur

Cadmium inhibits proteoglycan and procollagen production by cultured human lung fibroblasts

Chronic inhalation of cadmium at the workplace or in cigarette smoke is associated with emphysema, a disease characterized by extensive disruption of lung connective tissue. We have previously shown that cadmium, at noncytotoxic doses, inhibits fibroblast procollagen production in vitro, with maximal inhibitory effects of 69 +/- 6% (P < 0.01) at 30 &microM cadmium chloride (CdCl2). In this pap

Direct numerical simulation study of statistically stationary propagation of a reaction wave in homogeneous turbulence

A three-dimensional (3D) direct numerical simulation (DNS) study of the propagation of a reaction wave in forced, constant-density, statistically stationary, homogeneous, isotropic turbulence is performed by solving Navier-Stokes and reaction-diffusion equations at various (from 0.5 to 10) ratios of the rms turbulent velocity U′ to the laminar wave speed, various (from 2.1 to 12.5) ratios of an in

Altered expression of small proteoglycans, collagen, and transforming growth factor-beta 1 in developing bleomycin-induced pulmonary fibrosis in rats

The development of bleomycin-induced pulmonary fibrosis in rats was studied over a period of 21 d after an intratracheal instillation of bleomycin. The expression of three small proteoglycans (biglycan, decorin, and fibromodulin), collagen III and TGF-beta 1 was studied by RNA-transfer blot analysis. The proteoglycans were also studied by SDS-polyacrylamide gel electrophoresis and Western blots. T

Taking Volunteers Seriously : Progress report 1999-2007 The International Federation’s volunteering development

This report, commissioned by the Governing Board’s working group on volunteering and the secretariat of the International Federation of Red Cross and Red Crescent societies, aims to provide a picture of volunteering development since 1999 across the globe. It provides a broad outline of decision-making and commitments within the International Federation and describes the situation in National Soci

Lokal arbetsmarknadspolitik : Vem gör vad, hur och för vem?

Syftet i forskningsrapporten är att analysera om och i så fall hur statlig och kommunal arbetsmarknadspolitik överlappar varandra samt om arbetslösa riskerar att varken aktualiseras inom kommunal eller statlig arbetsmarknadspolitik. Forskningsrapporten omfattar en kunskapsöversikt av forskning om kommunal arbetsmarknadspolitik samt en intervjustudiemed nyckelpersoner inom statlig och kommunal arbe

A deterministic method for estimating free energy genetic network landscapes with applications to cell commitment and reprogramming paths

Depicting developmental processes as movements in free energy genetic landscapes is an illustrative tool. However, exploring such landscapes to obtain quantitative or even qualitative predictions is hampered by the lack of free energy functions corresponding to the biochemical Michaelis– Menten or Hill rate equations for the dynamics. Being armed with energy landscapes defined by a network and its

Differential expressions of mRNA for proteoglycans, collagens and transforming growth factor-beta in the human cervix during pregnancy and involution

During pregnancy and involution, an extensive remodelling of the human cervical connective tissue occurs. This cervical ripening is one of the most pronounced physiological remodelling processes known in human connective tissue. To investigate how the remodelling is accomplished, the levels of mRNA for collagen I and III, versican and three small proteoglycans, biglycan, decorin and fibromodulin,

Heparan/chondroitin/dermatan sulfate primer 2-(6-hydroxynaphthyl)-O-beta-D-xylopyranoside preferentially inhibits growth of transformed cells

Xylose forms the direct carbohydrate-protein link in extra- or pericellular proteoglycans (PGs) that are substituted with either chondroitin sulfate (CS)/dermatan sulfate (DS) and/or heparan sulfate (HS). Cell surface PGs carrying HS are important regulators of cell growth. Xylose coupled to an aromatic compound can enter cells and initiate either CS/DS synthesis or both HS and CS/DS synthesis, de

Paraurethral connective tissue in stress-incontinent women after menopause

OBJECTIVE: To study whether stress urinary incontinence after menopause is correlated to changes in the paraurethral connective tissue ultrastructure and metabolism.METHODS: Transvaginal biopsies were obtained from the paraurethral connective tissue in stress urinary incontinent women after menopause with and without estrogen replacement therapy, and from comparable controls. All the stress-incont