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Random self-decomposability and autoregressive processes

We introduce the notion of random self-decomposability and discuss its relation to the concepts of self-decomposability and geometric infinite divisibility. We present its connection with time series autoregressive schemes with a regression coefficient that randomly turns on and off. In particular, we provide a characterization of random self-decomposability as well as that of marginal distributio

Principles of epistemological accountability with methodological implications for measuring, assessing, and profiling human resilience

We propose two fundamental principles of epistemological accountability with critical methodological implications for studies designed to measure, assess, and/or profile human psychosocial resilience. Firstly, researchers involved in human psychosocial resilience studies owe it to the individuals and communities that they engage to disclose their motives and possible misreadings of the situations

200 and 300 MeV/nucleon nuclear reactions responsible for single-event effects in microelectronics

An experimental study of nuclear reactions between Si-28 nuclei at 200 and 300 MeV/nucleon and hydrogen or deuterium target nuclei was performed at the CELSIUS storage ring in Uppsala, Sweden, to collect information about the reactions responsible for single-event effects in microelectronics. Inclusive data on Si-28 fragmentation, as well as data on correlations between recoils and spectator proto

Charged-particle multiplicity measurement in proton-proton collisions at root s=0.9 and 2.36 TeV with ALICE at LHC

Charged-particle production was studied in proton-proton collisions collected at the LHC with the ALICE detector at centre-of-mass energies 0.9 TeV and 2.36 TeV in the pseudorapidity range vertical bar eta vertical bar < 1.4. In the central region (vertical bar eta vertical bar < 0.5), at 0.9 TeV, we measure charged-particle pseudo-rapidity density dN(ch)/d eta = 3.02 +/- 0.01(stat.)(-0.05)(+0.08)

Antennal transcriptome analysis of the chemosensory gene families in the tree killing bark beetles, Ips typographus and Dendroctonus ponderosae (Coleoptera: Curculionidae: Scolytinae)

Background: The European spruce bark beetle, Ips typographus, and the North American mountain pine beetle, Dendroctonus ponderosae (Coleoptera: Curculionidae: Scolytinae), are severe pests of coniferous forests. Both bark beetle species utilize aggregation pheromones to coordinate mass-attacks on host trees, while odorants from host and non-host trees modulate the pheromone response. Thus, the bar

Production of haloduracin by Bacillus halodurans using solid-state fermentation.

Bacillus halodurans was cultivated on wheat bran as a solid-state substrate and produced haloduracin, a bacteriocin, at about 245 AU per wheat bran. Supplementation of the bran with Lauria-Bertani broth decreased haloduracin production. However, production was stimulated by addition of Mg(2)SO(4) and K(2)HPO(4). The highest production was achieved at a wheat bran/moisture ratio of 1:1.8 and in the

Genetic polymorphisms, IGF-1, and oral contraceptive use in women from high-risk breast cancer families

Popular Abstract in Swedish Bröstcancer är den vanligaste cancerformen bland svenska kvinnor, fler än 7000 kvinnor insjuknar varje år. Mellan 5-10% av bröstcancerfallen tros bero på mutationer i arvsmassan som ärvts från föräldrarna. Om man har en ärftlig mutation i bröstcancergen 1 eller 2 (BRCA1 respektive BRCA2) löper man mellan 60-80% risk att drabbas av bröstcancer. Eftersom inte alla kvinnorBreast cancer is the most common cancer among Swedish women, affecting more than 7000 women each year. About 5-10% of all breast cancers are hereditary, with a monogenic inheritance pattern, but only 2-4% are explained by germline mutations in BRCA1 or BRCA2. BRCA1/BRCA2 mutation carriers have a 60-80% risk of developing breast cancer. Further, a large proportion of the breast cancers that are clu

Governing climate change transnationally: assessing the evidence from a database of sixty initiatives

With this paper we present an analysis of sixty transnational governance initiatives and assess the implications for our understanding of the roles of public and private actors, the legitimacy of governance 'beyond' the state, and the North-South dimensions of governing climate change. In the first part of the paper we examine the notion of transnational governance and its applicability in the cli

Hairdressers' occupational exposure to carcinogenic aromatic amines

The hairdresser occupation is classified as probably carcinogenic to humans based on an excess risk for urinary bladder cancer, but it is unclear if current work as a hairdresser entails such a risk. The overall aim of this thesis was to investigate if hairdressers have an ongoing exposure to selected carcinogenic aromatic amines. We recruited 295 hairdressers, 32 consumers of hair dyes and 60 co

Design of robust preparative chromatography

This work presents a methodology for analyzing and optimizing preparative chromatographic processes. It uses a model-based approach to find the critical process parameters, analyze the control space and suggest a design space that can be registered with the regulatory agencies. The methodology starts with a method for model calibration and validation. The model is then used to find an optimal oper

On the role of excited species in hydrogen combustion

Recently updated hydrogen combustion mechanism was combined with ozone decomposition reactions and extended by reactions of excited species: O(D-1), OH((2)Sigma(+)), and O-2(a(1)Delta g). The reliability and the accuracy of the rate constants pertinent to these excited species were evaluated. Many reactions proposed in the literature and implemented in other kinetic schemes were found irrelevant o

Constrained capacities for faster-than-Nyquist signaling

This paper deals with capacity computations of faster-than-Nyquist (FTN) signaling. It shows that the capacity of FTN is higher than the orthogonal pulse linear modulation capacity for all pulse shapes except the sinc. FTN signals can in fact achieve the ultimate capacity for the signal power spectral density (PSD). The paper lower and upper bounds the FTN capacity under the constraint of finite

The role of genetic variation and DNA methylation in human glucose metabolism and type 2 diabetes

Popular Abstract in Swedish Diabetes är en grupp sjukdomar som alla kännetecknas av en förhöjd nivå av sockerarten glukos i blodet. Antalet individer som drabbas av diabetes ökar hela tiden, en utveckling som ses över hela världen. Bara i Sverige har drygt 5% av befolkningen diagnosen diabetes, motsvarande 484.400 personer i åldern 20-79 år. Typ 2 diabetes är den vanligaste formen av diabetes, ochThe incidence of diabetes is increasing worldwide, with the most prevalent form being type 2 diabetes. Two fundamental processes contribute to the development of type 2 diabetes: insulin resistance in target organs and insufficient insulin secretion from the pancreatic beta-cells. The aim of this thesis was to explore the role of DNA methylation and common genetic variation on glucose metabolism a

Lentivirus-Induced Dendritic Cells for Immunization Against High-Risk WT1(+) Acute Myeloid Leukemia

Wilms' tumor 1 antigen (WT1) is overexpressed in acute myeloid leukemia (AML), a high-risk neoplasm warranting development of novel immunotherapeutic approaches. Unfortunately, clinical immunotherapeutic use of WT1 peptides against AML has been inconclusive. With the rationale of stimulating multiantigenic responses against WT1, we genetically programmed long-lasting dendritic cells capable of pro