Published 12 September 2021 Photo: Pixabay / Gerd Altmann Immeasurable time bias exaggerates drug benefits in pharmacoepidemiological studies due to exposure misclassification arising from the inability to measure in-hospital medications in many health care databases. Read the paper at https://academic.oup.com/ije/article/50/3/987/6048410

https://www.lupop.lu.se/article/analytical-approaches-minimizing-immeasurable-time-bias-cohort-studies - 2025-05-09

Published 13 September 2021 Interrupted time-series (ITS) designs are a robust and increasingly popular non-randomized study design for strong causal inference in the evaluation of public health interventions. Read the paper at https://academic.oup.com/ije/article/50/3/1011/5937253

https://www.lupop.lu.se/article/reflection-modern-methods-common-error-segmented-regression-parameterization-interrupted-time-series - 2025-05-09

Published 13 September 2021 Photo: Pixabay / www_slon_pics We report the current status of CKD registries in Europe in relation to their data collection on patients not on KRT so that in the future we may investigate to what extent also their data may be used for similar purposes, like collaborative research on CKD trajectories and patient outcomes. Read the paper at https://academic.oup.com/ndt/a

https://www.lupop.lu.se/article/snapshot-european-registries-chronic-kidney-disease-patients-not-kidney-replacement-therapy - 2025-05-09

Published 14 September 2021 Photo: Pixabay / Gerd Altmann The aim of this study was to explore the potential misclassification and evaluate the completeness of esophageal cancer diagnoses in the FCR and HILMO, considering misclassification. Read the paper at https://www.tandfonline.com/doi/full/10.1080/0284186X.2020.1792547

https://www.lupop.lu.se/article/completeness-esophageal-cancer-diagnosis-finnish-cancer-registry-and-hospital-discharge-registry - 2025-05-09

Published 14 September 2021 Photo: pixabay The term of overadjustment bias is used to refer to different scenarios. Here, we propose a unified definition of overadjustment, with four types. Read the paper at https://journals.lww.com/epidem/Fulltext/2021/09000/Revisiting_Overadju…

https://www.lupop.lu.se/article/revisiting-overadjustment-bias - 2025-05-09

Published 15 September 2021 Photo: Pixabay / Gerd Altmann General population-based cohort studies provide solid evidence on mass Helicobacter pylori (HP) eradication effects. Self-reported questionnaires are occasionally used in such studies to ascertain the HP eradication history. However, reports on the reliability of these questionnaires are lacking. Read the paper at https://www.nature.com/art

https://www.lupop.lu.se/article/reliability-self-reported-questionnaire-epidemiological-investigation-helicobacter-pylori - 2025-05-09

Published 25 May 2018 Forskningsrådet Formas lanserar en ny satsning på forskning för en giftfri miljö, specifikt till projekt som kan öka kunskapen kring kombinationseffekter av kemikalier och substanser. Läs mer här.

https://www.lupop.lu.se/article/giftfri-miljo-i-fokus-ny-forskningssatsning - 2025-05-09

Published 15 September 2021 Photo: Pixabay / Ben Kerckx A cardiovascular mortality algorithm applied to administrative health records had moderate validity when compared to vital statistics data. Substantial variation existed across study sites representing different geographic locations and two healthcare systems. These variations may reflect different diagnostic coding practices and healthcare u

https://www.lupop.lu.se/article/validity-algorithm-identify-cardiovascular-deaths-administrative-health-records-multi-database - 2025-05-09

Published 16 September 2021 This commentary provides a practical perspective on epidemiological analysis within a single high-dimensional study of moderate size to consider a causal question. Read the paper at https://academic.oup.com/ije/article/50/3/1016/6140018

https://www.lupop.lu.se/article/reflection-modern-methods-building-causal-evidence-within-high-dimensional-molecular-epidemiological - 2025-05-09

Published 16 September 2021 Photo: Pixabay / Sasin Tipchai The value of accurate healthcare data has never been more apparent than during the past year, and there is increasing recognition of the important role surgical registries play in driving improved patient outcomes, patient safety, and academic research. Successful registries need to be responsive and adapt to the rapidly changing clinical

https://www.lupop.lu.se/article/future-surgical-registries - 2025-05-09

Published 17 September 2021 Photo: Pixabay / Gerd Altmann Molecular pathological epidemiology research provides information about pathogenic mechanisms. A common study goal is to evaluate whether the effects of risk factors on disease incidence vary between different disease subtypes. Read the paper at https://academic.oup.com/ije/article/50/3/1030/6114706

https://www.lupop.lu.se/article/reflection-modern-methods-causal-inference-considerations-heterogeneous-disease-etiology - 2025-05-09

Published 21 January 2021 Countries with the highest burden of maternal and newborn deaths and stillbirths often have little information on these deaths. Since over 81% of births worldwide now occur in facilities, using routine facility data could reduce this data gap. We assessed the availability, quality, and utility of routine labour and delivery ward register data in five hospitals in Banglade

https://www.lupop.lu.se/article/labour-and-delivery-ward-register-data-availability-quality-and-utility-every-newborn-birth - 2025-05-09

Published 21 January 2021 We reweighted the Malmö Diet and Cancer (MDC) study based on population register data on background variables, including socio-demographics and hospital admissions for both participants and the background population. Following individuals from baseline in 1991-1996 and at most until 2016, we studied mortality (all-cause, cancer, and CVD), incidences (cancer and CVD), and

https://www.lupop.lu.se/article/can-validity-cohort-be-improved-reweighting-based-register-data-evidence-swedish-mdc-study - 2025-05-09

Published 9 April 2018 A project jointly conducted by the Nordic national statistical institutes and funded by NordForsk was initiated in 2015. The project, Nordic Microdata Access Network (NordMAN), seeks to establish a single pan-Nordic solution to facilitate researchers' access to the Nordic metadata compiled for statistical purposes, and to provide an overview of the existing Nordic registers.

https://www.lupop.lu.se/article/nordman-facilitates-researchers-access-nordic-microdata-and-provides-metadata-existing-nordic - 2025-05-09

Published 22 January 2021 Data from population-based cancer registries are often used to compare cancer survival between countries or regions. The ICBP SURVMARK-2 study is an international partnership aiming to quantify and explore the reasons behind survival differences across high-income countries. However, the magnitude and relevance of differences in cancer survival between countries have been

https://www.lupop.lu.se/article/exploring-impact-cancer-registry-completeness-international-cancer-survival-differences-simulation - 2025-05-09

Published 22 January 2021 We propose combining population-based register data with a nested clinical cohort to correct misclassification and unmeasured confounding through probabilistic quantification of bias. We have illustrated this approach by estimating the association between knee osteoarthritis and mortality. We used the Swedish Population Register to include all persons resident in the Skån

https://www.lupop.lu.se/article/probabilistic-quantification-bias-combine-strengths-population-based-register-data-and-clinical-0 - 2025-05-09

Published 22 January 2021 Based on discharge summaries and brain imaging reports, we estimated the positive predictive value (PPV) of a first-ever diagnosis code for ICH (ICD-10, code I61) for all patients in the Region of Southern Denmark (1.2 million) during 2009– 2017 according to either DNPR or DSR. We estimated PPVs for any non-traumatic ICH (a-ICH) and spontaneous ICH (s-ICH) alone (ie, with

https://www.lupop.lu.se/article/validity-intracerebral-hemorrhage-diagnoses-danish-patient-registry-and-danish-stroke-registry - 2025-05-09

Published 22 January 2021 Participants are members of the Maccabi Health Services, 40–65 years of age, with exquisitely detailed laboratory, medical diagnoses and medication data available in the Maccabi electronic medical records since 1998. Data collected through IRAP include genetic, sociodemographic, cognitive, brain imaging, lifestyle, and health-related characteristics at baseline and every

https://www.lupop.lu.se/article/israel-registry-alzheimers-prevention-irap-study-design-and-baseline-characteristics - 2025-05-09

Published 23 January 2021 Large prospective cohort studies may offer an opportunity to study the etiology and natural history of rare cancers. Cancer diagnoses in observational cohort studies are often self-reported. Little information exists on the validity of self-reported cancer diagnosis, especially rare cancers, in Canada. This study evaluated the validity of self-reported cancer diagnosis in

https://www.lupop.lu.se/article/importance-cancer-registry-linkage-studying-rare-cancers-prospective-cohorts - 2025-05-09

Published 23 January 2021 Acquisition of data on clinical performance is essential to improve outcomes in surgery. Large, national datasets allow hospitals to monitor events involving patient safety, complications, and benchmark against peer hospitals and facilitate quality improvement (QI) development. Although clinical datasets are often preferable, administrative data also have potential for ac

https://www.lupop.lu.se/article/administrative-and-registry-databases-patient-safety-tracking-and-quality-improvement - 2025-05-09