A register-based approach to identifying treatment-resistant depression—Comparison with clinical definitions
Published 26 August 2020 Several definitions of treatment-resistant depression (TRD) are used for clinical research, but no verified model for use in register data exists. We aimed to compare a novel model created for use in register data—the Karolinska Institutet Model (KIM)–to the clinical definitions regarding the proportion of patients identified with TRD, their characteristics and clinical ou