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Aims: Privileged access interviewing (PAI) has traditionally been used to reach illicit drug users and other ‘hidden’ populations. How PAI data compare to other self-reported data have seldom been discussed. We compare data from patients in opioid substitution treatment (OST), gathered through PAI and researcher interviews, respectively, to investigate whether PAIs and researchers are reaching com

BACKGROUND: Several studies have examined the effect of community interventions on youth alcohol consumption, and the results have often been mixed. The aim of this study is to evaluate the effectiveness of a community intervention known as the Öckerö Method on adolescent alcohol consumption and perceived parental attitudes towards adolescent drinking. METHOD: The study is based on a quasi-experim

OBJECTIVES: This study examines the associations between ten family structure types and delinquency, including four groups of symmetrical and asymmetrical living arrangements. We also adjust for attachment to parents and parental monitoring. METHODS: Data are drawn from four cross-sectional surveys conducted between 2016 and 2019 in southern Sweden. The sample consists of 3,838 adolescents, aged 1

Background Illicit use of methadone and buprenorphine has been described as a growing problem in Sweden in recent years, and has been associated with an increased drug-related mortality. Critics claim that the substances have become popular among adolescents and that they function as a gateway to heroin use. The aim of this study is to investigate, firstly, the extent to which illicit use of metha

Background In this study we examine whether the association between internet use and drinking could be different for different types of internet activities among adolescents. We also adjust for a number of theoretically relevant factors such as peer influence, unstructured activities, impulsivity and parental monitoring. Method The data are drawn from four cross-sectional surveys from the years 20

Immunotherapy has shown limited success in acute myeloid leukemia (AML), indicating an incomplete understanding of the underlying immunoregulatory mechanisms. Here we identify an immune evasion mechanism present in 60% of AML cases, wherein primitive AML cells aberrantly express the lymphoid surface protein SLAMF6 (signaling lymphocyte activation molecule family member 6). Knockout of SLAMF6 in AM

PurposeThe purpose of this study is to empirically explore how contractual learning in public procurement is affected by organizational design.Design/methodology/approachTwo inductive case studies are based on semi-structured interviews and document analysis.FindingsThe author finds that the consolidation of economic, technical and legal tasks in specific units can strengthen contractual learning

Background: Exposure to per- and polyfluoroalkyl substances (PFAS) has been associated with lower bone mineral content (BMC) and density (BMD) in children, but prospective studies remain limited. We aimed to investigate associations between prenatal and childhood PFAS exposure and BMC/BMD at age 9 years, following up on our previous findings from age 7 years. Methods: We used data from the Odense

The importance of older adults’ participation in policymaking is increasingly recognized, but the nuanced participation processes remain insufficiently understood. This scoping review aims to map existing research on older adults’ participation in policymaking, focusing on who participates, their activities and contributions, resulting outputs and outcomes, and the enablers and barriers affecting

Interest in Jane Austen’s fiction and life has never been greater than today. Her narrative works and worlds live on 200 years after their publication not only through their own popularity, but also through numerous re-presentations in the forms of novels, movies, television series, and fan fictions that keep flourishing from her fictional worlds and characters. Austen’s novels, her settings, and

Denna avhandling utvecklar och utvärderar språkbaserade bedömningar som använder artificiell intelligens (AI) för att omvandla öppet språk till kvantitativa indikatorer och beskrivningar av psykiska hälsorelaterade konstruktioner. Medan slutna skalor länge har dominerat psykologiska bedömningar, är de begränsade av fasta svarsformat och kanske inte helt fångar komplexiteten i individers upplevelseThis thesis develops and evaluates language-based assessments that use artificial intelligence (AI) to transform open-ended language into quantitative indicators and descriptions of mental health related constructs. While closed-ended scales have long dominated psychological assessment, they are limited by fixed response formats and may not fully capture the complexity of individuals’ experiences.

BackgroundIbrutinib, a Bruton tyrosine kinase inhibitor, prolongs progression-free survival when added to immunochemotherapy as first line treatment. The ENRICH trial compared the chemotherapy-free combination of ibrutinib and the anti-CD20 antibody rituximab (ibrutinib–rituximab) with standard immunochemotherapy (R-CHOP [rituximab–cyclophosphamide, doxorubicin, vincristine, and prednisolone] or b