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Background: Actinomycetes of the genus Streptomyces are renowned for their highly developed and diverse specialized metaboliс pathways, and there is an extensive body of data on their specific and pleiotropic levels of regulation. Much less is known about routes leading to essential metabolites in this genus. In this work, we focused on elucidating the function of the highly conserved across Strep

This study examines how two collaborating professions, midwifery and obstetrics, are influenced by women requesting caesarean sections. The empirical material consists of semi-structured interviews with Swedish midwives (n=6) and obstetricians (n=6). Analysed through Tilly’s terms, the categorical pair and triad, midwife and obstetrician function as complementary categories in a triad with the wom

A brain-computer interface (BCI) is a real-time system that converts a user’s brain activity into commands, enabling control over applications such as moving a cursor on the screen. This conversion is made possible by machine learning techniques and other algorithms. Historically, BCI research has focused on the analysis of brain signals offline. However, increasing computational power and algorit

Considering increasing living costs and lagging compensation levels in the welfare system, people on social welfare have difficulties accessing food to the extent needed. This presentation is based on a Swedish study aimed to reveal how migrant welfare recipients act, react, and reason in their management of their own scarce resources and those of others. Striving for ‘dignity’ took a prominent pl

The Milky Way provides the most detailed laboratory we have access to for studying the processes of galaxy formation and evolution. Modern large-scale surveys, most notably the Gaia mission, have revolutionised this field by revealing the extent to which the Galaxy is not a steady system, but dynamically active and rich in non-equilibrium features that preserve traces of past interactions. Underst

AIM: To explore nursing students' experiences of what they had learned and gained through participating in simulation-based communication training anchored in person-centred values.BACKGROUND: Person-centredness is a core component of nurses' work and an important part of it is person-centred communication. To promote patients' wellbeing and comfort, nursing students must become prepared during th

The fourth issue of the yearbook History of Intellectual Culture (HIC) features a thematic section on the production of knowledge related to the Holocaust. The contributions focus on the circulation of knowledge via letters and other forms of written communication within and among survivor historical commissions after the Second World War with an emphasis on the interplay of gender and other diffe

Loss and damage in fisheries is acknowledged in climate change policy and science but is both undefined and contested, and there is a lack of empirical exploration of the topic. This paper presents the first in-depth, empirical analysis of how fishers’ situated knowledge of socio-ecological changes can inform our understanding of loss and damage in fisheries. The paper conducts a case study from M

Contractile injection systems (CISs) are phage tail-like nanosyringes that mediate bacterial interactions by puncturing target cell membranes. Within these systems, Photorhabdus Virulence Cassettes (PVCs) can translocate toxins across eukaryotic target cell membranes and have been engineered to deliver diverse protein cargoes into non-natively-targeted organisms. Despite the structural insights in

Aims The Trump movement displays several key features of a populist movement with a strong leader and a broad unorganized base of followers opposed to a per-ceived liberal elite establishment. In 2024, Trump gained strong support from strata with low income, low education and Hispanic men, previously not strong support-ers of Republicans. This study investigates the preconditions for a populist moAims The Trump movement displays several key features of a populist movement with a strong leader and a broad unorganized base of followers opposed to a per-ceived liberal elite establishment. In 2024, Trump gained strong support from strata with low income, low education and Hispanic men, previously not strong support-ers of Republicans. This study investigates the preconditions for a populist mo

BACKGROUND: Few population studies have assessed the prevalence of various psychiatric disorders separately for sexual and gender minority groups, and none in an adolescent population. Given the increased mental health problems in sexual and gender minority groups combined, the present study aimed to estimate prevalence of mental disorders in separate sexual minority groups as well as gender disco

Background: Stroke and reduced survival are devastating complications of atrial fibrillation (AF). Biomarker-based ABC-AF risk scores improve risk prediction in AF, and risk-guided treatment recommendations may improve patient outcomes. Design: The ABC-AF study is a national, multicenter, prospective, registry-based, randomized controlled, parallel-group, open-label study. Its primary objective is

This study examined the prevalence, stability, and fluidity of sexual orientation as well as the prevalence of gender discontent. From a community sample (i.e., all adolescents of the age cohort were invited), this study analyzed data from 1513 adolescents (50.5% females), who replied to questions about sexual attraction on at least one of three occasions (age 14: n = 623; age 15: n = 1322; and ag

Obesity is a known risk factor for poor breast cancer outcomes, but its impact on endocrine therapy efficacy remains unclear. While the ATAC trial suggests reduced effectiveness of aromatase inhibitors (AIs) in women with obesity, the BIG 1–98 trial found no significant differences. Clinical and biological evidence indicates that obesity may impair AI efficacy by increasing aromatase activity and

Green ammonia synthesis from nitrogen via photocatalysis and electrocatalysis has emerged as a pivotal research focus in sustainable chemical processes. The efficient catalytic reduction of nitrogen necessitates concurrent nitrogen activation and hydrogen evolution suppression, representing a significant challenge. In this study, CuAu bimetallic-modified TiO2 catalysts were developed and engineere

Large cardiac rhabdomyomas can disturb hemodynamic flow. Tuberous sclerosis complex is the most common cause of cardiac rhabdomyoma in fetuses. Recently, a mammalian target of rapamycin (mTOR) inhibitor effectively treated rhabdomyomas associated with tuberous sclerosis. Here, we report the effectiveness of an mTOR inhibitor in treating a fetus with large rhabdomyomas exhibiting severe heart failu

Trimetallic nickel–iron–molybdenum oxides are excellent electrocatalysts for alkaline water electrolysis despite experiencing severe molybdenum dissolution. While the impact of molybdenum on fresh samples is well-understood, its substantial loss during operation without compromising performance presents a unique puzzle. Here, we show that the initial presence of molybdenum induces the formation of

We reviewed papers on optimal conjunctive use of surface and groundwater (GW) with application in dry regions. Selected papers from the last 25-year period were reviewed using the PRISMA method. We show that with increasing scarcity of water, objectives of models developed for optimal conjunctive use have become more environmentally and socially oriented. About two-thirds of the studies are dedica