Sökresultat
Filtrera
Filtyp
Din sökning på "*" gav 542810 sökträffar
Design of stochastic trigger boundaries for rural communities evacuating from a wildfire
Well-planned evacuation is an effective and often necessary tool to protect life in communities threatened by wildfire. In previous incidents, community evacuations have been called too late resulting in entrapment, such as in Mati, Greece in 2018. The most reliable method to determine the safe time to call an evacuation is through trigger boundaries, perimeters on the landscape surrounding a comm
Assessing the Legality: Are Requirements to Provide Infection Disease Tests a Form of Forced Bodily Intervention?
Prolonged deep-ocean carbonate chemistry recovery after the Paleocene-Eocene Thermal Maximum
The Paleocene-Eocene Thermal Maximum (PETM) is a hyperthermal event at ∼56 Ma ago, caused by rapid and massive carbon releases into the ocean-atmosphere system. Currently, the PETM ocean acidification is mainly quantified in the surface ocean. By contrast, PETM carbonate chemistry changes of the deep ocean, a larger carbon reservoir, are largely qualitatively constrained by sedimentary calcium car
TIA – akut handläggning och behandling minskar strokerisk
TIA is defined as an episode of neurological deficit with sudden onset, caused by focal cerebral or retinal ischemia lasting less than 24 hours. A tissue-based definition has been proposed but its application has been challenging, in part as its use requires magnetic resonance imaging. In most cases the diagnosis is solely based on history as provided by the patient. The diagnosis can therefore be
Recruitment of C4b-binding protein is not a complement evasion strategy employed by Staphylococcus aureus
Complement offers a first line of defence against infection through the opsonization of microbial pathogens, recruitment of professional phagocytes to the infection site and the coordination of inflammatory responses required for the resolution of infection. Staphylococcus aureus is a successful pathogen that has developed multiple mechanisms to thwart host immune responses. Understanding the prec
ERT and image analysis for estimating water and solute transport across the capillary fringe
EndoC-βH5 cells are storable and ready-to-use human pancreatic beta cells with physiological insulin secretion
Objectives: Readily accessible human pancreatic beta cells that are functionally close to primary adult beta cells are a crucial model to better understand human beta cell physiology and develop new treatments for diabetes. We here report the characterization of EndoC-βH5 cells, the latest in the EndoC-βH cell family. Methods: EndoC-βH5 cells were generated by integrative gene transfer of immortal
Fast, automated, continuous energy scans for experimental phasing at the BioMAX beamline
In X-ray macromolecular crystallography (MX), single-wavelength anomalous dispersion (SAD) and multi-wavelength anomalous dispersion (MAD) techniques are commonly used for obtaining experimental phases. For an MX synchrotron beamline to support SAD and MAD techniques it is a prerequisite to have a reliable, fast and well automated energy scan routine. This work reports on a continuous energy scan
Measurements of moisture content of waste materials with frequency domain reflectometry
Optical coherence properties of Kramers' rare-earth ions at the nanoscale for quantum applications
Rare Earth (RE) ion doped nanomaterials are promising candidates for a range of quantum technology applications. Among RE ions, the so-called Kramers' ions possess spin transitions in the GHz range at low magnetic fields, which allows for high-bandwidth multimode quantum storage, fast qubit operations as well as interfacing with superconducting circuits. They also present relevant optical transiti
Bindestrecksvänner i den relationella ekonomin
Reanalysis of neutron-capture elements in the benchmark r-rich star CS 31082-001
We revisit the abundances of neutron-capture elements in the metal-poor ([Fe/H] = -2.9) r-process-rich halo star CS 31082-001. Partly motivated by the development of the new near-ultraviolet Cassegrain U-band Efficient Spectrograph for the Very Large Telescope, we compiled an expanded line list for heavy elements over the range 3000-4000 Å, including hyperfine structure for several elements. Combi
Innovative three-dimensional models for understanding mechanisms underlying lung diseases : powerful tools for translational research
Chronic lung diseases result from alteration and/or destruction of lung tissue, inevitably causing decreased breathing capacity and quality of life for patients. While animal models have paved the way for our understanding of pathobiology and the development of therapeutic strategies for disease management, their translational capacity is limited. There is, therefore, a well-recognised need for in
Sustainability in anaesthesia and intensive care - an obligation to turn danger into opportunity
Eye movements in visual impairment
This Special Issue describes the impact of visual impairment on visuomotor function. It includes contributions that examine gaze control in conditions associated with abnormal visual development such as amblyopia, dyslexia and neurofibromatosis as well as disorders associated with field loss later in life, such as macular degeneration and stroke. Specifically, the papers address both gaze holding
Argonaute, Vault, and Ribosomal Proteins Targeted by Autoantibodies in Systemic Lupus Erythematosus
OBJECTIVE: To expand, in an unbiased manner, our knowledge of autoantigens and autoantibodies in patients with systemic lupus erythematosus (SLE) and evaluate their associations with serological and clinical variables. METHODS: Human proteome arrays (> 21,000 proteins) were screened with serum from patients with SLE (n = 12) and healthy controls (n = 6) for IgG and IgA binding. Top hits were valid
The servitization of game meat: recreational hunting in-between wildlife care and holistic tourist experiences
Background and aim The paper is based on a study of hunting tourism enterprising in Sweden. The paper demonstrates how game meat is ascribed different, sometimes conflicting values in the moral economy of commercial hunting and identifies an emerging process of servitization of the game meat. Recreational hunting in Sweden can be described as embedded in two different but overlapping cultural and
A practical solution to the saturation problem in feedforward control for measurable disturbances
This paper treats the problem of control signal saturation caused by feedforward control from measurable load disturbances. An efficient feedforward compensator will often give significant peaks in the control signal at fast changes in the load disturbance. These peaks may cause the control signal to reach a saturation limit. In the paper, it is shown that the anti-windup function may cause unnece
Engineered human Diamond-Blackfan anemia disease model confirms therapeutic effects of clinically applicable lentiviral vector at single-cell resolution
Diamond-Blackfan anemia is a rare genetic bone marrow failure disorder which is usually caused by mutations in ribosomal protein genes. In the present study, we generated a traceable RPS19-deficient cell model using CRISPR-Cas9 and homology-directed repair to investigate the therapeutic effects of a clinically applicable lentiviral vector at single-cell resolution. We developed a gentle nanostraw