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AIMS: This nationwide study aimed to analyse the first 2 years of routine clinical use of cangrelor in all Swedish patients undergoing percutaneous coronary intervention (PCI). METHODS AND RESULTS: This observational Swedish Coronary Angiography and Angioplasty Registry (SCAAR) study identified 915 cangrelor-treated patients. As 899 were ST-segment elevation myocardial infarction (STEMI)-patients

We investigate the relation between large negative house price co-movements in the cross-section of US cities and the national business cycle. The occurrences of large negative house price co-movements across cities cluster over time and these clusters are closely linked to NBER recession dates. A simple co-movement measure that aggregates large negative city-level house price returns reliably pre

Electron density determination based on structure factors obtained through powder X-ray diffraction has so far been limited to high-symmetry inorganic solids. This limit is challenged by determining high-quality structure factors for crystalline urea using a bespoke vacuum diffractometer with imaging plates. This allows the collection of data of sufficient quality to model the electron density of

Advanced preservation injury (PI) after intestinal transplantation has deleterious short-and long-term effects and constitutes a major research topic. Logistics and costs favor rodent studies, whereas clinical translation mandates studies in larger animals or using human material. Despite diverging reports, no direct comparison between the development of intestinal PI in rats, pigs, and humans is

Production studies show that anaphoric reference is bimodal. Speakers can introduce a referent in speech by also using a localizing gesture, assigning a specific locus in space to it. Referring back to that referent, speakers then often accompany a spoken anaphor with a localizing anaphoric gesture (i.e., indicating the same locus). Speakers thus create visual anaphoricity in parallel to the anaph

Quantum dots (QDs) can serve as near perfect energy filters and are therefore of significant interest for the study of thermoelectric energy conversion close to thermodynamic efficiency limits. Indeed, recent experiments in [Nat. Nano. 13, 920 (2018)1748-338710.1038/s41565-018-0200-5] realized a QD heat engine with performance near these limits and in excellent agreement with theoretical predictio

Background: Sentinel lymph node biopsy (SLNB) is standard staging procedure for nodal status in breast cancer, but lacks therapeutic benefit for patients with benign sentinel nodes. For patients with positive sentinel nodes, individualized surgical strategies are applied depending on the extent of nodal involvement. Preoperative prediction of nodal status is thus important for individualizing axil

Objective To investigate the contemporary presentation of pituitary metastases. Patients Thirty-eight patients diagnosed with pituitary metastases from 1996 to 2018 in Sweden. Methods Pituitary metastases were confirmed by histopathology (n = 27) or considered highly likely according to radiological findings, including rapid tumor progression (n = 11). Medical records were reviewed and sellar imag

This article suggests algorithms for diagnosis and treatment of scaphoid fractures. A clinical suspected scaphoid fracture without signs of fracture on conventional radiographs should have a supplementary MRI done within 5-7 days. Displaced fractures and all proximal fractures should be classified by CT. Fracture union should be evaluated by CT. 90 procent of non- or minimally displaced waist frac

International guidelines recommend that the treatment of patients with infective endocarditis (IE) should be directed by a multidisciplinary endocarditis team. The aim of this study was to describe the first-year experience of multidisciplinary rounds by the endocarditis team in Scania, Sweden. This was a retrospective study on all possible and definitive IE episodes that were assessed by the endo

Using the left-right symmetric model as an illustrative example, we suggest a simple and straightforward way of constraining the W′ mass directly from the decay of the Higgs boson to two photons. The proposed method is generic and applicable to a diverse range of models with a W′-boson that couples to the Standard Model-like Higgs boson. Our analysis exemplifies how the precision measurement of th

Purpose: To investigate possible roles of T helper (Th) cells, regulatory T cells (Tregs), and the recently mapped Th-like Tregs in patients with polypoidal choroidal vasculopathy (PCV). Methods: In this prospective case-control study, we obtained fresh venous blood from patients with PCV (n = 24), age-matched healthy controls (n = 32), and patients with neovascular AMD (n = 45). All participants

Babesia är en malarialiknande parasit som är välkänd inom veterinärmedicinen och som sprids med fästingar till människor samt som möjlig transfusionssmitta. Symtom kan vara feber, trötthet och muskelvärk, men hos immunsupprimerade patienter eller vid rubbad mjältfunktion kan organsvikt och livshotande sjukdom snabbt uppkomma. I USA rapporteras drygt 2 000 fall per år. En ny studie från Sydsverige Babesia is a malaria-like, intraerythrocytic parasite with more than 100 different species. It is a zoonosis and some of the species are transmitted to humans by ticks and also as a possible transfusion-transmitted infection. In Sweden the disease has been well known in veterinary medicine for a long time, but only a few but severe cases have been published in humans during the last decades. Commo

Affluent blood flow through a complicated net of vessels supplies skeletal bone tissue with oxygen and nutrients. Due to accidental events or physiological processes, the blood supply might be deficient or even disrupted, and the healthy bone decays in a process that, for the hip location, is denoted as osteonecrosis of the femoral head (ONFH) or avascular femoral head necrosis. Early diagnosis is

Objective: The aim of this study was to review the literature to identify studies reporting repair of erosions in rheumatoid arthritis (RA). Method: A systematic literature search for publications on the repair of erosions was performed in PubMed and Embase, limited to human adults and published in English. Titles, abstracts, and full reports of articles identified were screened by the first autho