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Destination Restaurants’ Practices and the Production of Locality : The Case of Michelin Restaurants in China

Dining plays a pivotal role in the travel experience, with numerous studies identifying the significant impacts of restaurant attributes on tourists’ destination experiences and their sense of place. The identified attributes include the origin of food produce, menu design, the physical and social servicescape, and restaurant reputation, all of which have the potential to enhance customers’ sense

Two minus one road equals improved quality of life

Background: Sundbyberg municipality (part of greater Stockholm) has reconstructed a traditional two-lane road, with an allowed speed limit of 30 km/h, into a road with one car lane and two bicycle lanes, one on either side of the car lane (a “two minus one road”). The aim was to increase traffic safety and accessibility, especially for bicyclists and pedestrians Method: The design used was a befor

Second and third TNF inhibitors in European patients with axial spondyloarthritis : effectiveness and impact of the reason for switching

Objective: To investigate real-world effectiveness of tumor necrosis factor inhibitors (TNFi) in patients with axial spondyloarthritis (axSpA) and the association with (i) treatment line (second and third TNFi-series) and (ii) reason for withdrawal from the preceding TNFi [lack of efficacy (LOE) vs adverse events (AE)]. Methods: Prospectively collected routine care data from 12 European registries

The Metabolomic Profile of Microscopic Colitis Is Affected by Smoking but Not Histopathological Diagnosis, Clinical Course, Symptoms, or Treatment

Microscopic colitis (MC) is classified as collagenous colitis (CC) and lymphocytic colitis (LC). Genetic associations between CC and human leucocyte antigens (HLAs) have been found, with smoking being a predisposing external factor. Smoking has a great impact on metabolomics. The aim of this explorative study was to analyze global metabolomics in MC and to examine whether the metabolomic profile d

Surface guided ring gantry radiotherapy in deep inspiration breath hold for breast cancer patients

Purpose: This study investigated the use of surface guided radiotherapy (SGRT) in combination with a tomotherapy treatment mode using discrete delivery angles for deep inspiration breath hold (DIBH) treatments of breast cancer (bc). We aimed to assess the feasibility and dosimetric advantages of this approach. Materials and methods: We evaluated camera occlusion in the Radixact treatment system bo

Perspective on Industrial Electrification and Utility Scale PV in the Arctic Region

Two concurrent trends may fundamentally change how we understand the role of solar PV at high latitudes. Until now, relatively low annual insolation in combination with low electricity demand during the summer months has not favoured PV in the Arctic. However, continued decreases in costs for PVs in combination with increasing electricity demand from industrial electrification is quickly changing

ANALYSIS OF PLANT PHENOLOGY DYNAMICS IN SPAIN FROM 1983 TO 2020 USING SATELLITE IMAGERY

This study spatially analyzes plant phenology and its variations over time in mainland Spain and the Balearic Islands. To conduct the analysis, a nearly 40-year span time series (1983-2020) was generated by merging NDVI vegetation index values from satellite images sourced from NOAA-AVHRR and MODIS sensors. The phenological variables were calculated using TIMESAT 3.3, which extracted 13 phenometri

Finite-Time Dynamics of an Entanglement Engine : Current, Fluctuations and Kinetic Uncertainty Relations

Entanglement engines are autonomous quantum thermal machines designed to generate entanglement from the presence of a particle current flowing through the device. In this work, we investigate the functioning of a two-qubit entanglement engine beyond the steady-state regime. Within a master equation approach, we derive the time-dependent state, the particle current, as well as the associated curren

From giant clumps to clouds : IV. Extreme star-forming clumps on top of universal cloud scaling relations in gas-rich galaxies

The clumpy nature of gas-rich galaxies at cosmic noon raises the question of universality of the scaling relations and average properties of the star-forming structures. Using controlled simulations of disk galaxies and varying only the gas fraction, we show that the influence of the galactic environments (large-scale turbulence, tides, and shear) contributes, together with the different regime of

Venetoclax Drug Increases the Apoptosis of T and B Acute Lymphoblastic Leukemia Cells by Reducing the Expression of BCL-2

Venetoclax, a specific inhibitor of the BCL2 protein, is administered for the treatment of acute lymphoblastic leukemia. However, despite being utilized in conjunction with chemotherapy, the drug exhibits instances of resistance. The exact mechanisms responsible for this resistance remain relatively obscure. Within the context of this investigation, the study aimed to explore the involvement of an

Abundances in eight bulge stars from the optical and near-infrared

Context. The abundances of the α-elements are key for understanding the early chemical enrichment of the Galactic bulge. The elements of interest present lines in different wavelength regions, and some of them show lines only in part of the spectra. In the present work, the CNO trio, the a-elements Mg, Si, Ca, and Ti, and odd-Z Na and Al are examined as measured from optical and H-band lines. Aims

Integration of Specialized Palliative Care with Oncological Treatment in Patients with Advanced Pancreatic Cancer

INTRODUCTION: The incidence of pancreatic cancer is around 5 in 100,000, and the 5-year survival is poor. Pancreatic cancer patients have a high disease-specific burden of symptoms, and palliative chemotherapy has varying side effects. The American Society of Clinical Oncology (ASCO) suggests integrating specialized palliative care (SPC) with standard oncological treatment for pancreatic cancer pa

Constructive Dissonance in the Cloud: Adaptive Out-of-Phase Scheduling for Periodic Tasks

In the realm of cloud computing, the prevalence of intra-phase congestion due to concurrent periodic requests from a multitude of clients frequently results in heightened resource consumption, elongated queuing times, and prolonged response durations. To tackle these challenges, this paper presents a groundbreaking 'Adaptive Out-of-Phase Scheduling' technique, utilizing a server-side PID controlle

Numerical Investigation of Engine Performance and Emission Characteristics of an Ammonia/Hydrogen/n-Heptane Engine Under RCCI Operating Conditions

This paper examines the potential of using ammonia (NH 3) as a primary fuel in heavy-duty engines for decarbonization, with some challenges yet to be addressed. It presents a numerical study of a Reactivity Controlled Compression Ignition engine, where pilot diesel is used to ignite the premixed ammonia/air mixture. The numerical model and combustion mechanism are validated against engine experime

Light-Induced Metastable Hidden Skyrmion Phase in the Mott Insulator Cu2OSeO3

The discovery of a novel long-lived metastable skyrmion phase in the multiferroic insulator Cu2OSeO3 visualized with Lorentz transmission electron microscopy for magnetic fields below the equilibrium skyrmion pocket is reported. This phase can be accessed by exciting the sample non-adiabatically with near-infrared femtosecond laser pulses and cannot be reached by any conventional field-cooling pro

Secondary ice production : An empirical formulation and organization of mechanisms among simulated cloud-types

Clouds are essential elements within Earth's atmosphere, posing a challenge for cloud-resolving models in understanding the creation of new cloud ice particles from existing ice and liquid phases. Such ice initiation determines cloud microphysical and radiative properties, influencing cloud phase, precipitation and cloud extent/properties. To address this challenge effectively, it proves beneficia