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Identification of Alcohol Use Prior to Major Cancer Surgery : Timeline Follow Back Interview Compared to Four Other Markers

BACKGROUND: The postoperative complication rate is 30-64% among patients undergoing muscle-invasive and recurrent high-risk non-muscle-invasive bladder cancer surgery. Preoperative risky alcohol use increases the risk. The aim was to evaluate the accuracy of markers for identifying preoperative risky alcohol.METHODS: Diagnostic test sub-study of a randomized controlled trial (STOP-OP trial), based

Preferences for Follow-Up Procedures among Patients Lost to Follow-Up after Smoking Cessation Intervention among Therapists-An Interview Study

Achieving high follow-up rates after smoking cessation interventions (SCIs) is a general challenge. The aim of this study was to identify preferences among patients and therapists for improving follow-up rates and to assess smoking status at 6 months among patients lost to follow-up. From the Danish STOPbase for Tobacco and Nicotine, which collects data on SCI across health care, 20 representative

Determining the Affinity and Kinetics of Small Molecule Inhibitors of Galectin-1 Using Surface Plasmon Resonance

The beta-galactoside-binding mammalian lectin galectin-1 can bind, via its carbohydrate recognition domain (CRD), to various cell surface glycoproteins and has been implicated in a range of cancers. As a consequence of binding to sugar residues on cell surface receptors, it has been shown to have a pleiotropic effect across many cell types and mechanisms, resulting in immune system modulation and

An Amperometric Lactate Sensor Based on a NAD+-Analog and Lactate Dehydrogenase Coimmobilized on Reticulated Vitreous Carbon

A NAD+-analog was coimmobilized with lactate dehydrogenase (LDH) on reticulated vitreous carbon (RVC) to give an amperometric lactate biosensor. Both LDH and the NAD+ -analog were bound covalently with carbodiimide to the surface of the porous RVC-material. The electrode was operated in a FIA-arrangement in the presence or absence of a soluble mediator. Meldola Blue. The stability was poor wh

Development of a simple detector for microbial metabolism, based on a polypyrrole dc resistometric device

A simple device for the detection of metabolic effects was constructed based on a conducting polymer (polypyrrole) coated with an agarose layer containing immobilised yeast cells. A galvanostatic potentiometric method was used to measure the resistance of the sensor, thus minimising interferences from fluctuations in solution conductivity. The resulting biosensor was used as a simple indicator of

Preparation and characterization of composite polymers exhibiting both selective molecular recognition and electrical conductivity

Electrically conducting composite particles were manufactured consisting of a morphine-imprinted methacrylic acid-ethyleneglycoldimethacrylate copolymer interpenetrated with a polypyrrole network. The imprinted polymer was first prepared and then used as a host polymer into which pyrrole monomer was adsorbed. After partial drying of the pyrrole-saturated host polymer, an oxidant was adsorbed, when

The MAX-III storage ring

MAX-III is a 700 MeV storage ring for synchrotron radiation that is being built at MAX-lab. The ring will provide radiation in the UV and IR spectral regions. The ring will have a 100 MHz RF system combined with a 500 MHz passive Landau cavity. The lattice is compact, with combined function magnets. The magnets are integrated into the girder providing for ease of alignment.

A systematic evaluation of seven different scores representing the EAT–Lancet reference diet and mortality, stroke, and greenhouse gas emissions in three cohorts

Different approaches have been used for translation of the EAT–Lancet reference diet into dietary scores that can be used to assess health and environmental impact. Our aim was to compare the different EAT–Lancet diet scores, and to estimate their associations with all-cause mortality, stroke incidence, and greenhouse gas emissions. We did a systematic review (PROSPERO, CRD42021286597) to identify

Adherence to a healthy lifestyle including sleep and sedentary behaviors and risk of metabolic dysfunction-associated steatotic liver disease in Chinese adults

Objective: Various lifestyle factors including smoking, alcohol, physical activity, sedentary behavior, diet quality, sleep behavior, and overweight have been related to metabolic dysfunction-associated steatotic liver disease (MASLD); however, their joint impact on risk of MASLD is not well known. We prospectively investigated the association between a combination of lifestyle factors and risk of

Enzymic synthesis of monosaccharide-amino acid conjugates

Enzymatic condensation between amino acids and monosaccharides was studied. A screening involving the OH-containing amino acids serine and threonine and the monosaccharide substrates for the enzymes α-N-acetylgalactosaminidase, α-galactosidase, α-mannosidase, β-xylosidase, and β-galactosidase was carried out. Enzymatic condensation was observed with α-mannosidase and α-N-acetylgalactosaminidase. P

New methods for separation and recovery of biomolecules

New methods and applications in the separation of biomolecules are reviewed, with an emphasis on the large-scale recovery of proteins. Highlights include the advent of flow-through particles in perfusion chromatography, which allows for very high flow rates, while retaining a high chromatographic efficiency.

Fenestrated Endovascular Repair using Short Tipped Distal Components with “No Cross” Concept to Prevent Crushing of Target Vessel Bridging Stents

ObjectiveTo compare and evaluate early and midterm outcomes of a “no cross” novel approach with short tip vs. standard tip introducer systems for all distal components to prevent target vessel bridging stent kink or collapse during fenestrated endovascular aortic repair (FEVAR).MethodsA retrospective analysis was conducted on all patients who underwent FEVAR at a tertiary referral centre between O