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Combined genetic deficiencies of the classical complement pathway are strongly associated with both systemic lupus erythematosus and primary Sjögren's syndrome

ObjectiveComplete genetic deficiency of the complement component C2 is a strong risk factor for monogenic systemic lupus erythematosus (SLE), but whether heterozygous C2 deficiency adds to the risk of SLE or primary Sjögren's syndrome (pSS) has not been studied systematically. Here we investigated heterozygous C2 deficiency and C4 copy number variation in relation to clinical manifestations in SLE

Exploring the most important factors related to self-perceived health among older men in Sweden: a cross-sectional study using machine learning

Objective To evaluate which factors are the most strongly related to self-perceived health among older men and describe the shape of the association between the related factors and self-perceived health using machine learning.Design and setting This is a cross-sectional study within the population-based VAScular and Chronic Obstructive Lung disease study (VASCOL) conducted in southern Sweden in 20

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The Majdan, the annexation of Crimea, and the ongoing war in eastern Ukraine have significantly affected the Ukrainian state, politics, and society over the last six years. The objective of this master thesis is now to shed light on how the assumptions of nation and identity altered and how Petro Porošenko, a leading state actor, produced representations of national identity in times of crisis and

Sorting out the sorting in omnichannel retailing

The increasing complexity of today's omnichannels has led to challenges with logistics efficiency and customer utility. In this paper, we show how retailers address these challenges by sorting goods at multiple points across the logistics network and inside each material-handling node. As contemporary research on the omnichannel sorting phenomenon is limited and fragmented, we conduct an abductive

The transformation from manual to smart warehousing: An exploratory study with Swedish retailers

PurposeTo meet customers' expectations on shorter lead times, high product availability, flexibility, and variation in delivery and return options, retailers have turned their attention to warehousing and are making big investments in technology. Currently, technology providers are pushing for smart warehousing, a new and under-researched phenomenon. This study aims to conceptualize the term and e

The altered drivers of evapotranspiration trends around the recent warming hiatus in China

This study focuses on the trends and the causes of variation in actual evapotranspiration (AET) around the warming hiatus over China by a comprehensive analysis applying various temporal–spatial methods. It is observed that the annual AET showed a different trend around 2000 for China as a whole. By employing segmented regression analysis for detecting warming hiatus points, high temporal inconsis

CCTV as a Socio-technology

The authors discuss CCTV, which is now established as a mature and ubiquitous technology. They review existing research on CCTV as backdrop to introduce an alternative re-narration that stresses its use as an advanced information technology—a socio-technology. Central to this perspective is the recognition that system effectiveness hinges on a match of individual, organizational and technological

European Stabilization Policy After the Covid-19 Pandemic: More Flexible Integration or More Federalism?

Crises are a major driving force behind cooperation in the European Union. This holds also for monetary and fiscal policy. During severe crises, cooperation has been enlarged and intensified. The recent covid-19 pandemic is a clear example of this pattern. The pandemic has had huge impact on the conduct of stabilization policies in the EU. Public debt has grown rapidly in many EU member states. Th

The UX Defined UX Designer Is No More

UX is now an acknowledged business process across several industries. Having grown out of Human Factors, Human-Computer Interaction and Interaction Design, UX is increasingly witnessing scholarly attention outside these historical roots. However, this popularity of UX also seems to have caused a broadening of the UX concept – where several non-UX professional roles and perspectives now shape its m