An orientation of a graph G is a digraph D obtained from G by replacing each edge by exactly one of the two possible arcs with the same endvertices. For each v∈V(G), the indegree of v in D, denoted by dD-(v), is the number of arcs with head v in D. An orientation D of G is proper if dD-(u)≠dD-(v), for all uv∈E(G). The proper orientation number of a graph G, denoted by χ→(G), is the minimum of the

This is a contribution to the controversy which of individual or collective intentionality is more fundamental. I call it the fundamentality-question. In a first step, I argue that it is really two questions. One is about sense and one about reference. The first is: Can one grasp or understand the concept individual intentionality and, correspondingly, individuality, on the one hand, without grasp

This book explores innovations in public management, including establishing a corporate vision, strategizing an organisation and change management. Chapters provide a valuable frame of reference for the 21st century manager of public services by assessing the renewal of existing practices such as strategic costing, performance management, digitization and procurement and innovations in management

Every organization exists for a reason – a reason that describes what that organization wants to achieve. Sharing a vision is therefore fundamental in every organization. A vision should explain why people do things together and sets the direction for their future actions. This chapter deals with the characteristics and role of visions in public organizations. For such organizations, it is vital tThis chapter focuses on the role and importance of visions in the management of public-sector organizations. The management literature generally defines this rationale as the “mission” of the organization. Mission statements that define an organization are widely believed to be antecedents to the strategic development process. The literature provides a multiplicity of definitions and characteristi

In this chapter management of public services is introduced as a topic. The tasks and general challenges for management are described. Also, the specific setting for public services is elaborated on and discussed. In this uncertain environment management needs to be flexible and responsive to new ideas and practices to fulfil its purpose. The ability to adapt quickly to unpredictable changes in ci

The academic debate in migrant entrepreneurship has mainly focused on movements from emerging economies into developed economies. Anecdotal evidence has suggested that the highest impact is generated by migrants in/from emerging economies. To extend this academic discussion in the Latin-American context, this study investigates why migrants are more entrepreneurial than natives. By adopting the hu

This study analyses the influence of environmental and individual conditions on the quality and the speed of entrepreneurial re-entries in emerging economies after a business failure. We propose a conceptual framework supported by the institutional economic theory to study the influence of environmental conditions; and human and social capital to study the influence of individuals’ skills, experie

Background: Despite standard-of-care androgen-deprivation therapy and an increasing number of treatment options, the mortality rate for prostate cancer remains high. Progress to metastatic castration-resistant prostate cancer (mCRPC) necessitates additional treatments. Abiraterone acetate plus prednisone or prednisolone (AAP) prolongs survival in chemotherapy-naive and docetaxel-experienced patien

A library of donor-acceptor system consisting of cyclopentadithiophene-based polymer photocatalysts have been designed and synthesized. Among all photocatalysts, the active PCPDTBSO achieved hydrogen evolution rates of 24.6 mmol h–1 g–1 with apparent quantum yields of 8.7 % at 500 nm. More importantly, combined the results of photocatalytic efficiency, apparent quantum yield, the time-resolved flu

Background: New-onset atrial fibrillation (NEW-AF) following ST-segment elevation myocardial infarction (STEMI) is a common complication, but the true prognostic impact of NEW-AF is unknown. Additionally, the optimal treatment of NEW-AF among patients with STEMI is warranted. Methods: A large cohort of consecutive patients with STEMI treated with percutaneous coronary intervention were identified

We prove that for k ≫; 4√n regular resolution requires length nω(k) to establish that an ErdÅ's-Rényi graph with appropriately chosen edge density does not contain a k-clique. This lower bound is optimal up to the multiplicative constant in the exponent and also implies unconditional nω(k) lower bounds on running time for several state-of-the-art algorithms for finding maximum cliques in graphs.

There is an urgent need for treatments that not only reduce bacterial infection that occurs during wounding but that also target the accompanying excessive inflammatory response. TCP-25, a thrombin-derived antibacterial peptide, scavenges toll-like receptor agonists such as endotoxins and lipoteichoic acid and prevents toll-like receptor-4 dimerization to reduce infection-related inflammation in v

In 1966, Gallai asked whether every connected graph has a vertex that is common to all longest paths. The answer to this question is negative. We prove that the answer is positive for outerplanar graphs and 2-trees. Another related question was raised by Zamfirescu in the 1980s: Do any three longest paths in a connected graph have a vertex in common? The answer to this question is unknown. We prov

Low-molecular-weight (MW) polyols are organic osmolytes influencing water activity. We have investigated the effects of polyol molecules (glycerol and sorbitol) on the optical and triplet excitation dynamics of light-harvesting complex 2 (LH2) from Rhodobacter (Rba.) sphaeroides in buffer-detergent solutions. The resonance Raman spectroscopy demonstrated that, on increasing glycerol and sorbitol v

Light pollution, light in the wrong place at the wrong time, is an emerging environmental issue with wide-ranging consequences. It interferes with the fundamental 24 h light–dark cycle, and has biological effects at all levels, from molecules to ecosystems, including human health and welfare. Here, exemplified by flood-lit churches, artificial lights compromise the survival of resident bats, as da