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Assessing the external validity of the VALIDATE-SWEDEHEART trial

AIMS: The VALIDATE-SWEDEHEART trial was a registry-based randomized trial comparing bivalirudin and heparin in patients with acute myocardial infarction undergoing percutaneous coronary intervention. It showed no differences in mortality at 30 or 180 days. This study examines how well the trial population results may generalize to the population of all screened patients with fulfilled inclusion cr

Investigation of oxidation mechanisms in magnesium by density functional theory

Magnesium (Mg) is a metallic material with a great range of potential applications. It can be used as the lightest structure material in automotive and aviation sectors, medical implants, hydrogen storge, etc. In such applications, oxidation and corrosion reactions play a critical role in the effectiveness of use. Therefore, deeper understanding of the fundamental mechanisms of oxidation and corro

The functional and structural diversity of rhythmic communication across species

Research on the rhythmic communication (RC) of nonhuman animals is undergoing a period of great effervescence and expansion. Here, we synthesize this rapidly growing literature with the aim of mapping RC forms and usage contexts in an unprecedented diversity of taxa, spanning insects, fish, frogs, birds and mammals. We see this as a first large-scale effort toward charting the functional and struc

A study of job polarization in Sweden from an urban-rural perspective

This study is an explorative examination of changes in employment, revenue, and firm structure for low, mid, and high-skill firms in urban and rural areas in Sweden from 2007 to 2019, using skill groups based on education levels. For employment in Sweden in general, we find evidence of job upgrading. In the city of Stockholm we also document job polarization in the sense that employment in both lo

Influence of Fuel and Technology on Particle Emissions from Biomass Cookstoves─Detailed Characterization of Physical and Chemical Properties

Globally, 3 billion people rely on solid biomass fuel for their everyday cooking, most often using inefficient cooking practices, leading to high exposure levels of household air pollution. This is subsequently associated with negative health and climate impact. Further, the inefficient use of biomass fuels applies pressure on natural forests, resulting in deforestation, loss of biodiversity, and

Variable stressor exposure shapes fitness within and across generations

Environmental variation has long been considered a key driver of evolutionary change, predicted to shape different strategies, such as genetic specialization, plasticity, or bet-hedging to maintain fitness. However, little evidence is available with regards to how the periodicity of stressors may impact fitness across generations. To address this gap, I conducted a reciprocal split-brood experimen

Uppmaningar i Idrott och hälsa : Kommunikation i språkligt varierade klasser

Idrott och hälsa är ett ämne där den största delen av innehållet förmedlas muntligt, vilket gör talspråket till en avgörande faktor för elevernas förståelse och delaktighet. Den muntliga kommunikationens betydelse är särskilt relevant i klasser med stor språklig mångfald där elever med svenska som andraspråk kan ha svårt att följa instruktioner och delta fullt ut om de inte förstår det talade språ

The association of travel distance and other patient characteristics with breast cancer stage at diagnosis and treatment completion at a rural Rwandan cancer facility

Background: Butaro Cancer Center of Excellence (BCCOE) was founded to serve Rwanda’s rural low-income population, providing subsidized cancer diagnosis and treatment with transport stipends for the lowest-income patients. We examined whether travel distance to BCCOE was associated with advanced-stage diagnoses and treatment completion. Methods: We conducted a retrospective cohort study using medic

Spatiotemporal evolution of Ediacaran-Cambrian (ca. 551–523 Ma) sponges in South China and their simulated contributions to marine oxygenation

The origin and evolution of sponges have attracted interest, not only because they are among the most basal metazoans, but also because they act as important ecological engineers in the ocean. Previous research suggested that sponge groups diversified quickly during the Cambrian Series 2, while Terreneuvian sponge fossils are conspicuously rare and poorly substantiated. Yet, an increasing number o

Anorectal prolapse after anorectal reconstruction : Incidence and risk factors according to the ARM-Net Consortium

Aim: There is a knowledge gap regarding which patients with anorectal malformations (ARMs) are at highest risk of anorectal prolapse (AP), and which risk factors predispose to AP in ARM. The aims of the study were to define the frequency of AP after ARM reconstruction, and explore risk factors. Method: Data from the ARM-Net registry inserted between 2007 and 2023 were used. Inclusion criteria were

Diagnostic and prognostic relevance of inflammatory markers in surgically treated thymic epithelial tumors : An international multicenter study

Background: Complementary prognostic markers are needed in thymic epithelial tumors (TETs) to aid patient stratification and determine the most appropriate follow-up strategies. This study aimed to assess the diagnostic and prognostic relevance of blood-based inflammatory markers in a large cohort of surgically treated TET patients. Material and Methods: A total of 743 TET patients who underwent s

Moving the Body and the Mind : Links between Emotion and Rhythmic Communication and the underlying Neurobiological Mechanisms

Rhythmic patterning is a widespread structural trait of animal (including human) communication. Concomitantly, a key role of communication is to convey and/or induce emotion. The expression and modulation of emotion is also hypothesized to be a key mechanism for the evolution of rhythmic synchronization in humans. Despite the centrality of both rhythm and emotion to human and nonhuman communicatio

The developmental trajectory of rhythmic abilities in humans and singing primates

Rhythmicity is a composite competence that spans perceptual, motor, and socio-cognitive abilities. This is highly salient when adopting a developmental perspective, as we do in this chapter that reviews data from humans and other singing primate taxa with a close (gibbons) or remote (indri lemurs) phylogenetic relatedness to our species. The findings we review show that rhythmicity develops as an

How animals produce rhythm : an overview of ethological mechanisms for rhythmic communication

Animals communicate with a staggering diversity of rhythmic signals, yet behind all this diversity lies a small number of ethological mechanisms. In this chapter, we provide a quick review of how animal produce rhythmic signals based on these mechanisms, which span tremulation, percussion, bodily displays, stridulation, tymbalation, aerodynamic sound production (including vocalisation), as well as

Prenatal PFAS exposure associates with DXA assessed markers of adiposity in 7-year-old children from the Odense Child Cohort

The global increase in childhood overweight and obesity presents significant public health concerns due to its long-term health implications. Emerging evidence suggests that exposure to endocrine disrupting chemicals, such as per- and polyfluoroalkylated substances (PFAS), may be obesogenic and contribute to adiposity. This study aimed to investigate the association between prenatal PFAS exposure

Use of nanotechnology for safe agriculture and food production : Challenges and limitations

Nanotechnology offers promising perspectives for revolutionizing agriculture by enhancing productivity and sustainability. Although the global agricultural nanotechnology market was valued at US$ 352.4 billion in 2023 and is estimated to reach US$ 868.9 billion by 2031, concerns about adverse environmental effects persist. This review summarizes the latest developments and perspectives of nanotech