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Acquired inhibitors of blood coagulation are rare but of clinical importance. Prothrombin is a vitamin K-dependent protein, and acquired antibodies toward prothrombin are often associated with the presence of lupus anticoagulant. We describe a previously healthy 70-year-old man presenting with both hemorrhage and thrombosis as well as a prolonged prothrombin time. At arrival at the hospital, he wa
This thesis aimed to develop an understanding that could simplify the developmentof "ready-to-use peanut (Arachis hypogaea L.) sauce commonly consumed in Mozambique,where traditional preparation requires extensive cooking (5-6 hours). The study investigatesthe effects of cooking time on phenolic compounds, sensory properties, and the impact ofdifferent drying methods and dextrin on the sauce's mic
Digital technologies have revolutionized the manufacturing landscape, enhancing productivity, quality, and sustainability. Industry 5.0 emphasizes human–machine collaboration to achieve the Sustainable Development Goals (SDGs) while prioritizing human centrality in technologically advanced systems. Therefore, Industry 5.0 signifies a paradigm shift from techno-centric to human-centric systems to a
A search for T and Y vector-like quarks produced in proton-proton collisions at a centre-of-mass energy of 13 TeV and decaying into Wb in the fully hadronic final state is presented. The search uses 139 fb−1 of data collected by the ATLAS detector at the LHC from 2015 to 2018. The final state is characterised by a hadronically decaying W boson with large Lorentz boost and a b-tagged jet, which are
Differential measurements of Higgs boson production in the τ-lepton-pair decay channel are presented in the gluon fusion, vector-boson fusion (VBF), VH and tt¯H associated production modes, with particular focus on the VBF production mode. The data used to perform the measurements correspond to 140 fb−1 of proton-proton collisions collected by the ATLAS experiment at the LHC. Two methods are used
This paper reports the measurement of Higgs boson production in association with a tt¯ pair in the H→bb¯ decay channel. The analysis uses 140 fb-1 of 13 TeV proton–proton collision data collected with the ATLAS detector at the Large Hadron Collider. The final states with one or two electrons or muons are employed. An excess of events over the expected background is found with an observed (expected
BACKGROUND/OBJECTIVE: Bone remodeling is a critical process for skeletal health, and its dysregulation can lead to diseases like osteoporosis. While several Cyclin-Dependent Kinases (CDKs) are known to regulate bone metabolism, the function of CDK10 remains uncharacterized in this context. Human mutations in CDK10 cause the Al Kaissi syndrome, which involves severe skeletal defects, suggesting a
A search is performed for light, spin-0 bosons decaying into two photons in the 66 to 110 GeV mass range, using 140 fb−1 of proton-proton collisions at s = 13 TeV produced by the Large Hadron Collider and collected by the ATLAS detector. Multivariate analysis techniques are used to define event categories that improve the sensitivity to new resonances beyond the Standard Model. A model-independent
Cities worldwide face immense challenges in transitioning to a sustainable future. While being structurally and politically bound to continuous growth, the striving for a constant increase in production and consumption puts enormous pressure on our planet and its ecosystems. Degrowth has been proposed as a pathway to solving this dilemma. Although scholarly attention to urban degrowth has expanded
This paper presents measurements of top-antitop quark pair (tt¯) production in association with additional b-jets. The analysis utilises 140 fb−1 of proton–proton collision data collected with the ATLAS detector at the Large Hadron Collider at a centre-of-mass energy of 13 TeV. Fiducial cross-sections are extracted in a final state featuring one electron and one muon, with at least three or four b
Background The global prevalence of congenital heart disease (CHD) is increasing. Research on patient-reported outcomes (PROs) predominantly originates from high-income countries, resulting in an incomplete understanding of the true global burden of CHD from the patient perspective. Therefore, we described perceived health, psychological distress and quality of life (QoL) in a large sample of adul
Many extensions of the Standard Model, including those with dark matter particles, propose new mediator particles that decay into hadrons. This paper presents a search for such low mass narrow resonances decaying into hadrons using 140 fb−1 of proton-proton collision data recorded with the ATLAS detector at a centre-of-mass energy of 13 TeV. The resonances are searched for in the invariant mass sp
In Swedish feminist debates of the 1960s and 1970s, the productive woman was frequently constructed as the binary opposite of the non-productive woman. The former was associated with liberation, moral integrity, and independence. The latter was characterized in terms of passivity, laziness, and dependence. By engaging in paid labour, or by otherwise demonstrating her contribution to the greater go
INTRODUCTION: Sexual life is important for many people and may be limited by breathlessness. We evaluated associations between breathlessness and individuals' perceived satisfaction with sexual lives and explored mediating factors in this relationship. METHODS: A cross-sectional, online, population-based survey of Australian adults with key demographics (age, sex, rurality, state/territory) reflec
PURPOSE OF REVIEW: To summarize and critically interpret new evidence (from the last 12-18 months) on the associations between obesity and breathlessness, including epidemiology, physiological mechanisms, diagnostic challenges, and treatment approaches.RECENT FINDINGS: Multiple large cohorts confirm that obesity is one of the strongest independent predictors of exertional breathlessness. Recent wo
A search for the production of a Higgs boson and one or more charm quarks, in which the Higgs boson decays into a photon pair, is presented. This search uses proton-proton collision data with a centre-of-mass energy of s = 13 TeV and an integrated luminosity of 140 fb−1 recorded by the ATLAS detector at the Large Hadron Collider. The analysis relies on the identification of charm-quark-containing
INTRODUCTIONBoreal forests are crucial for mitigating global climate change by capturing and storing large amounts of atmospheric carbon dioxide. However, previously unmanaged primary boreal forests are being rapidly transformed to managed secondary forests to meet the rising global demand for materials and energy. Understanding the effects of boreal primary to managed secondary forest transformat
Proton–proton collision data recorded by the ATLAS detector in 2011, at a centre-of-mass energy of 7 TeV, have been used for an improved determination of the W-boson mass and a first measurement of the W-boson width at the LHC. Recent fits to the proton parton distribution functions are incorporated in the measurement procedure and an improved statistical method is used to increase the measurement
The ATLAS tile calorimeter (TileCal) is the hadronic sampling calorimeter covering the central region of the ATLAS detector at the Large Hadron Collider (LHC). This paper gives an overview of the calorimeter’s operation and performance during the years 2015–2018 (Run 2). In this period, ATLAS collected proton–proton collision data at a centre-of-mass energy of 13 TeV and the TileCal was 99.65% eff
