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Breast tomosynthesis and digital mammography: a comparison of breast cancer visibility and BIRADS classification in a population of cancers with subtle mammographic findings.

The main purpose was to compare breast cancer visibility in one-view breast tomosynthesis (BT) to cancer visibility in one- or two-view digital mammography (DM). Thirty-six patients were selected on the basis of subtle signs of breast cancer on DM. One-view BT was performed with the same compression angle as the DM image in which the finding was least/not visible. On BT, 25 projections images were

Development and Psychometric Evaluation of the Pain Impact Inventory.

Abstract Objectives: The aim of this study was to develop and psychometrically evaluate an instrument for measuring the impact of chronic pain on daily life. Methods: The study comprised 384 respondents (aged between 18-102 years) who reported chronic pain. The instrument "Pain Impact Inventory" (PII) was evaluated in terms of face, content, construct and criterion validity, as well as two reliabi

Stimulation of oestrogen receptor-expressing endothelial cells with oestrogen reduces proliferation of cocultured vascular smooth muscle cells.

1. Oestrogen reduces vascular smooth muscle cell proliferation in mouse vascular injury models. Data on the antiproliferative effect of oestrogen in cultured vascular smooth muscle cells (VSMC) are less conclusive than those obtained in whole animal studies. 2. In the present study, we investigated the hypothesis that oestrogen-induced attenuation of VSMC proliferation is facilitated by the presen

Prevalence and incidence of HIV-1 and HIV-2 before, during and after a civil war in an occupational cohort in Guinea-Bissau, West Africa.

OBJECTIVES:: To study prevalence and incidence of HIV-1 and HIV-2 between 1990 and 2007 and to examine impact of the civil war in 1998-1999. We also wanted to investigate possible interaction between HIV-1 and HIV-2. DESIGN:: Open prospective cohort study of 4592 police officers in Guinea-Bissau, West Africa. METHODS:: Analysis of HIV-1 and HIV-2 prevalence and incidence divided in 2-3 years time

Sternocutaneous fistulas after cardiac surgery: incidence and late outcome during a ten-year follow-up.

BACKGROUND: Sternocutaneous fistulas (SCFs) after cardiac surgery represent a complex surgical problem involving multiple hospital admissions, prolonged antibiotic treatment, and repeated debridements. Our objective was to identify the incidence of and risk factors for SCF, and to evaluate long-term survival. METHODS: A total of 12,297 patients underwent sternotomy for cardiac surgery between Janu

Phenotype associated with mutation in the recently identified autosomal dominant retinitis pigmentosa KLHL7 gene.

OBJECTIVE: To characterize the clinical phenotype, with an emphasis on electrophysiologic findings, in a family with autosomal dominant retinitis pigmentosa caused by mutation in the recently identified KLHL7 gene. METHODS: Eleven patients from a single family were selected from the Swedish retinitis pigmentosa register. Four patients had been examined 13 to 17 years earlier and underwent further

An epidemiological study of collagenous colitis in southern Sweden from 2001-2010.

AIM: To estimate the incidence of collagenous colitis (CC) in southern Sweden during 2001-2010. METHODS: Cases were identified by searching for CC in the diagnostic registers at the Pathology Departments in the county of Skåne. The catchment area comprised the south-west part of the county (394 307 inhabitants in 2010) and is a mixed urban and rural type with limited migration. CC patients that h

Associations between polysubstance use and psychiatric problems in a criminal justice population in Sweden.

BACKGROUND: Polysubstance use is common in substance users, and may complicate their clinical course. This study, in a criminal justice setting in Sweden, examines the association between the number of concurrently used substance types and psychiatric symptoms during 30 days before incarceration, while controlling for background variables such as family history (drug and alcohol problems, psychiat

Men and women on the move : Dramas of the road

This article comments on three post-Second-World-War road novels: Kerouac’s On the Road(1957), Robbins’s Even Cowgirls Get the Blues(1976), Atkinson’s Highways and Dance Halls(1995). Framing its perspective within the question of what is involved in creating a 20th-century ‘traveller identity’, it conceptualizes the road in terms of how it historically and generically emerged as a primarily male t

Apo-lipoproteins, lipids and risk of cancer.

The epidemiological evidence for an obesity-cancer association is solid, whereas the association between obesity-associated lipoprotein levels and cancer is less evident. We investigated circulating levels of Apolipoprotein A1 (ApoA1), Apolipoprotein B (ApoB), LDL-cholesterol (LDL-C) and HDL-cholesterol (HDL-C) and association to risk of overall cancer and common cancer forms. The Malmö Diet and C

Are Purkinje Cell Pauses Drivers of Classically Conditioned Blink Responses?

Several lines of evidence show that classical or Pavlovian conditioning of blink responses depends on the cerebellum. Recordings from cerebellar Purkinje cells that control the eyelid and the conditioned blink show that during training with a conditioning protocol, a Purkinje cell develops a pause response to the conditional stimulus. This conditioned cellular response has many of the properties t

An African-American family with dystonia.

The genetic cause of late-onset focal and segmental dystonia remains unknown in most individuals. Recently, mutations in Thanatos-associated protein domain containing, apoptosis associated protein 1 (THAP1) have been described in DYT6 dystonia and associated with some cases of familial and sporadic late-onset dystonia in Caucasians. We are not aware of any previous descriptions of familial dystoni

On the error control for multistep methods applied to ODEs with invariants and DAEs in multibody dynamics

A modified local error model is developed for numerical integration of ODEs with invariants. The basic idea is to use a commutativity relationship that holds for implicit state-space form methods. A new implicit state-space form predictor is developed from which error estimates can be obtained by predictor-corrector difference: This technique is demonstrated through the preliminary examples in thi

Sustainability of transport biofuels from a legal perspective

The article investigates the notion of transport biofuels, their possible advantages and disadvantages in comparison to traditional fossil fuels, and sustainability requirements that need be stated to their quality and production methods from a legal perspective. The research results indicate that the understanding of what makes the quality and production of transport biofuels sustainable is still

Structural modeling of generalized prejudice: The role of social dominance, authoritarianism, and empathy

Structural equation modeling on questionnaire data showed that prejudice toward different target groups can be represented in terms of a general prejudice factor. Distinction of classical and modern prejudice only increased model fit marginally. In two separate samples (paper and pencil vs. Internet) several structural models of the relationship between key individual difference variables and prej