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Metastable precursor structures in hydrogen-infused super duplex stainless steel microstructure – An operando diffraction experiment

We report the evolution of metastable precursor structures during hydrogen infusion in the near-surface region of a super duplex stainless steel. Grazing-incidence x-ray diffraction was employed to monitor, operando, the lattice degradation of the austenite and ferrite phases. Electrochemical hydrogen charging resulted in the splitting of the diffraction peaks of the austenite phase, suggesting th

Samarasiṃha and the Early Transmission of Tājika Astrology

One of the earliest preserved Sanskrit works on Perso-Arabic (Tājika) astrology, the thirteenth-century Karmaprakāśa of Samarasiṃha (also known as the Manuṣyajātaka, Tājikatantrasāra or Gaṇakabhūṣaṇa), is examined with particular attention to subgenre, distinctive content and likely Arabic-language sources. On the basis of a comparison of the extant text of the Karmaprakāśa with excerpts attribute

A Note on the Indian Planetary Exaltations and their Greek-Language Sources

A close examination of the lists of planetary exaltations given by two of the earliest known Sanskrit authors on horoscopic astrology – Mīnarāja and Sphujidhvaja – solves the confusion surrounding Mīnarāja’s idiosyncratic assignment of degrees and suggests that both authors, and indeed all later Indian astrological literature, depended for this doctrine on a single, Greek-language source.

The Jewel of Annual Astrology : A Parallel Sanskrit-English Critical Edition of Balabhadra’s Hāyanaratna

The Jewel of Annual Astrology is an encyclopaedic treatise on Tājika or Sanskritized Perso-Arabic astrology, dealing particularly with the casting and interpretation of anniversary horoscopes. Authored in 1649 CE by Balabhadra Daivajña, court astrologer to Shāh Shujāʿ – governor of Bengal and second son of the Mughal emperor Shāh Jahān – it casts light on the historical development of the Tājika s

Warming weathers changes the chemical composition of oat hulls

The current threats of climate change are driving attention away from the petrochemical industry towards more sustainable and bio‐based production processes for fuels and speciality chemicals. These processes require suitable low‐cost starting material. One potential material assessed here is the oat hull. Its overall chemical composition has so far not been fully characterized. Furthermore, it is

Invasive heritage: Risks and values in cultivation

Gardeners have always used plants of different origins, moving them around to new environments, working hard to make the plants survive and thrive under new conditions. Certain plant varieties have proved to be particularly vital, have a long history as cultivars, and are today understood as heritage plants. Many have spread over centuries and are today regarded as ‘belonging’ and as more or less Gardeners have always used plants of different origins, moving them around to new environments, working hard to make the plants survive and thrive under new conditions. Certain plant varieties have proved to be particularly vital, have a long history as cultivars, and are today understood as heritage plants. Many have spread over centuries and are today regarded as ‘belonging’ and as more or less

IMAGINE study protocol of a clinical trial : a multi-center, investigator-blinded, randomized, 36-month, parallel-group to compare the effectiveness of motivational interview in rehabilitation of older stroke survivors

BACKGROUND: Rehabilitation pathways are crucial to reduce stroke-related disability. Motivational Interviewing (MI), as a person-centered complex intervention, aimed to empower and motivate, and could be a resource to improve rehabilitation outcomes for older stroke survivors. The IMAGINE project aims to assess the impact of MI, as a complement to standard geriatric rehabilitation, on functional i

The Ubiquitin Proteasome System in Neuromuscular Disorders : Moving Beyond Movement

Neuromuscular disorders (NMDs) affect 1 in 3000 people worldwide. There are more than 150 different types of NMDs, where the common feature is the loss of muscle strength. These disorders are classified according to their neuroanatomical location, as motor neuron diseases, peripheral nerve diseases, neuromuscular junction diseases, and muscle diseases. Over the years, numerous studies have pointed

Antibacterial Fusion Proteins Enhance Moraxella catarrhalis Killing

Moraxella catarrhalis is a human-specific commensal of the respiratory tract and an opportunistic pathogen. It is one of the leading cause of otitis media in children and of acute exacerbations in patients with chronic obstructive pulmonary disease, resulting in significant morbidity and economic burden. Vaccines and new immunotherapeutic strategies to treat this emerging pathogen are needed. Comp

Intrusion Detection in Digital Twins for Industrial Control Systems

Nowadays, the growth of advanced technologies is paving the way for Industrial Control Systems (ICS) and making them more efficient and smarter. However, this makes ICS more connected to communication networks that provide a potential platform for attackers to intrude into the systems and cause damage and catastrophic consequences. In this paper, we propose implementing digital twins that have bee

Psychological distress and problem gambling in elite athletes during covid-19 restrictions—a web survey in top leagues of three sports during the pandemic

COVID-19 and lockdown strategies may affect mental health and addictive behavior differently in the population, and elite athletes are among the professions clearly affected by the pandemic. This study in top elite athletes aimed to study current perceived psychological influence from COVID-19 and symptoms of depression, anxiety and changes in alcohol drinking, gambling behavior and problem gambli

Coronavirus Disease 2019 Related Clinical Studies : A Cross-Sectional Analysis

Objective: The quality and rationality of many recently registered clinical studies related to coronavirus disease 2019 (COVID-19) needs to be assessed. Hence, this study aims to evaluate the current status of COVID-19 related registered clinical trial. Methods: We did an electronic search of COVID-19 related clinical studies registered between December 1, 2019 and February 21, 2020 (updated to Ma

Discovery of epi-enprioline as a novel drug for the treatment of vincristine resistant neuroblastoma

Neuroblastoma is a childhood solid tumour originating from undifferentiated neural progenitor cells of the sympathetic nervous system. Drug resistance of childhood cancer neuroblastoma is a serious clinical problem. In the present study, we aimed to identify novel drugs that can inhibit the growth and survival of chemoresistant neuroblastoma. High-throughput screening identified a small molecule,

Molecular structure of maltoside surfactants controls micelle formation and rheological behavior

Hypothesis: The anomeric configuration (α or β) of n-hexadecyl-D-maltopyranoside (C16G2) has been shown to affect the morphology of the micelle, from elongated for α-C16G2 to worm-like micelles for β-C16G2. The entanglement of worm-like micelles often leads to strong modifications of the rheological behavior of the system and, as such, the anomeric configuration of C16G2 could also provide the pos

Gene expression signature of acquired chemoresistance in neuroblastoma cells

Drug resistance of childhood cancer neuroblastoma is a serious clinical problem. Patients with relapsed disease have a poor prognosis despite intense treatment. In the present study, we aimed to identify chemoresistance gene expression signatures in vincristine resistant neuroblastoma cells. We found that vincristine-resistant neuroblastoma cells formed larger clones and survived under reduced ser

Investigating the digital media engagements of very young children in the homes : Reflecting on methodology and ethics

In the media and communications field, research investigating the digital media engagements of very young children at home has largely been restricted to survey methods relying on parental self-reports. Recognizing that qualitative approaches can provide insights in families’ practices, values, and attitudes, we argue for the fruitfulness of an ethnographic perspective, drawing on three cases from

Robust PID control of propofol anaesthesia: uncertainty limits performance, not PID structure

Background and objective: New proposals to improve the regulation of hypnosis in anaesthesia based on the development of advanced control structures emerge continuously. However, a fair study to analyse the real benefits of these structures compared to simpler clinically validated PID-based solutions has not been presented so far. The main objective of this work is to analyse the performance limit