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During severe storms, high waves and water levels can reach the subaerial portion of the beach and cause significant morphological change at elevations where the waves cannot reach under typical sea conditions. Coastal dunes may suffer direct wave impact and erode, increasing the likelihood of overwash and breaching, potentially flooding low-lying areas behind the dunes. Barrier islands are also v
Considerable efforts have been put into analyzing the obtained surface roughness during turning operations. However, knowledge is still lacking on how to model the arithmetic mean surface roughness Ra through using a general model applicable for all workpiece materials and process parameters. Further, the influence of the minimum chip thickness on the obtained surface roughness needs to be clarifi
The TIR-containing protein C (TcpC) of uropathogenic Escherichia coli strains is a powerful virulence factor by impairing the signaling cascade of Toll-like receptors (TLRs). Several other bacterial pathogens like Salmonella, Yersinia, Staphylococcus aureus but also non-pathogens express similar proteins. We discuss here the pathogenic potential of TcpC and its interaction with TLRs and TLR-adapte
Birds from semi-arid regions may suffer dehydration during hot, dry seasons with low food availability. During this period, both energetic costs and water requirements for thermoregulation increase, limiting the scope of activity. For granivorous birds feeding on dry seeds, this is a major challenge and availability of water may affect the value of food. Water availability could (1) increase the v
Cellular Neural Networks are characterized by simplicity of operation. The network consists of a large number of nonlinear processing units; called cells; that are equally spread in the space. Each cell has a simple function (sequence of multiply-add followed by a single discrimination) that takes an element of a topographic map and then interacts with all cells within a specified sphere of intere
Objectives To determine the causes and predictors of mortality in systemic sclerosis (SSc). Methods Patients with SSc (n=5860) fulfilling the American College of Rheumatology criteria and prospectively followed in the EULAR Scleroderma Trials and Research (EUSTAR) cohort were analysed. EUSTAR centres completed a structured questionnaire on cause of death and comorbidities. Kaplan-Meier and Cox pro
Prolactin is best known for its involvement in lactation, where it regulates mechanisms that supply nutrients for milk production. In individuals with pathological hyperprolactinemia, glucose and fat homeostasis have been reported to be negatively influenced. It is not previously known, however, whether prolactin regulates lipogenesis in human adipose tissue. The aim of this study was to investiga
BackgroundFood habits, nutrient needs and intakes differ between males and females, although few nutritional studies on patients with coeliac disease (CD) have reported results stratified by gender. ObjectivesTo compare energy and nutrient intakes among 13-year olds diagnosed with CD in early childhood with those of a non-coeliac (NC) age- and gender-matched control group, and also with estimated
This paper presents a measurement of the cross-section for high transverse momentum W and Z bosons produced in pp collisions and decaying to allhadronic final states. The data used in the analysis were recorded by the ATLAS detector at the CERN Large Hadron Collider at a centre-of-mass energy of root s = 7 TeV and correspond to an integrated luminosity of 4.6 fb(-1). The measurement is performed b
Array-based genotyping platforms have during recent years been established as a valuable tool for the characterization of genomic alterations in cancer. The analysis of tumor samples, however, presents challenges for data analysis and interpretation. For example, tumor samples are often admixed with nonaberrant cells that define the tumor microenvironment, such as infiltrating lymphocytes and fibr
The thesis aims to explore subjective experiences of everyday occupation, social interaction and the view of the worker role among people with psychiatric disabilities(PD), while also addressing the importance of day centre attendance. The thesis consists of one qualitative study, exploring which characteristics in everyday occupation provide meaning to people with PD, and three quantitative studi
Taxane based chemotherapy is the standard of care treatment in castration resistant prostate cancer (CRPC). There is convincing evidence that taxane therapy affects androgen receptor (AR) but the exact mechanisms have to be further elucidated. Our studies identified c-jun as a crucial key player which interacts with AR and thus determines the outcome of the taxane therapy given. Docetaxel (Doc) an
SNP allelic copy number data provides intensity measurements for the two different alleles separately. We present a method that estimates the number of copies of each allele at each SNP position, using a continuous-index hidden Markov model. The method is especially suited for cancer data, since it includes the fraction of normal tissue contamination, often present when studying data from cancer t
High-quality computer graphics let mobile-device users access more compelling content. Still, the devices' limitations and requirements differ substantially from those of a PC. This survey of mobile graphics research describes current solutions in terms of specialized hardware (including 3D displays), rendering and transmission, visualization, and user interfaces.
Review of the two last volumes in Martin Schwarz Lausten's six volume study on Church and Jewry in Denmark.
The integration of risk reduction and climate change adaptation has become an urgent task in addressing increasing urban risk more effectively and efficiently. This paper analyses the extent to which climate change adaptation is integrated into the policies and regulatory frameworks that guide urban risk reduction in Nicaragua, and discusses related progress. The results reveal significant progres
