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More Representation, Less Radicalism : How Compulsory Voting Was Defended in Europe

This chapter examines how the practice of compulsory voting was debated in Belgium and France at the turn of the twentieth century. Two principal arguments in favour of compulsory voting stand out. One builds on the concept of ‘true’, ‘exact’ and ‘mirror’ representation. Abstention, it is argued, creates a ‘false’ and ‘corrupt’ image of majority will; by summoning all voters, parliaments will be m

Hermann Heller on Democratic Self-Defence : Militant Democracy Revisited

The debate on militant democracy is very much consumed by the question of whether legal restrictions against antidemocratic parties are justified. By contrast, this paper gestures towards a social conception of democratic self-defence. It does so by examining Hermann Heller’s ideas on the origins and solutions to antidemocratic threats. Arguing against Schmitt’s ‘authoritarian liberalism’, Heller

Autoimmune (type 1) diabetes

Autoimmune (type 1) diabetes mellitus is a chronic disease without a cure. It affects primarily young people but may be diagnosed at any age. Strong genetic susceptibility characterizes the most common form of autoimmune diabetes in children younger than 18 years of age. Autoimmune diabetes is generally assumed to be hereditary, although the majority of patients do not have a family history of aut

Performance Bounds in Positioning with the VIVE Lighthouse System

The VIVE lighthouse system is evaluated for indoor positioning of micro unmanned aerialcvehicles (MUAVs). A detailed mathematical analysis is provided, including a Cramer-Raocbound derivation and performance analysis of the MUAV state estimate. The lighthousecmeasurements are fused with inertial measurements in a multiplicative extended Kalmanfilter (MEKF). We consider two implementations, one wit

Associations between perfluoroalkyl substances and serum lipids in a Swedish adult population with contaminated drinking water

BACKGROUND: Exposures to perfluoroalkyl substances (PFAS) have shown positive associations with serum lipids in previous studies. While many studies on lipids investigated associations with perfluorooctane sulfonic acid (PFOS) and perfluorooctanoic acid (PFOA), there are only a few studies regarding other PFAS, such as perfluorohexane sulfonic acid (PFHxS). The purpose of the current study is to i

Spectral induced polarization of limestones: time domain field data, frequency domain laboratory data and physicochemical rock properties

With advances in data acquisition and processing methods, spectral inversion of time domain (TD) induced polarization (IP) data is becoming more common. Geological interpretation of inverted spectral parameters, for instance Cole–Cole parameters, often relies on results from systematic laboratory measurements. These are most often carried out with frequency domain (FD) systems on sandstone samplesWith advances in data acquisition and processing methods, spectral inversion of time domain (TD) induced polarization (IP) data is becoming more common. Geological interpretation of inverted spectral parameters, for instance Cole–Cole parameters, often relies on results from systematic laboratory measurements. These are most often carried out with frequency domain (FD) systems on sandstone samples

Fungerar entreprenörskapsutbildning på universitetsnivå? Ett balanserat lärande för att utveckla kunskaper att företa sig entreprenöriella karriärer

I kapitel 4 utforskar Gustav Hägg hur väl entreprenörskapsutbildningar fung- erar och varför vi överhuvudtaget ska satsa på utbildning i entreprenörskap. Kapitelförfattaren lyfter inledningsvis att entreprenören ofta associeras med enhör- ningen och att det inte sällan är framgångsrika individer som lyfts fram. Enligt Hägg är detta missvisande då entreprenören kommer i alla möjliga skepnader och fI kapitel 4 utforskar Gustav Hägg hur väl entreprenörskapsutbildningar fung- erar och varför vi överhuvudtaget ska satsa på utbildning i entreprenörskap. Kapitelförfattaren lyfter inledningsvis att entreprenören ofta associeras med enhör- ningen och att det inte sällan är framgångsrika individer som lyfts fram. Enligt Hägg är detta missvisande då entreprenören kommer i alla möjliga skepnader och f

Tauopathy-Associated Tau Fragment Ending at Amino Acid 224 Is Generated by Calpain-2 Cleavage

BACKGROUND: Tau aggregation in neurons and glial cells characterizes tauopathies as Alzheimer's disease (AD), progressive supranuclear palsy (PSP), and corticobasal degeneration (CBD). Tau proteolysis has been proposed as a trigger for tau aggregation and tau fragments have been observed in brain and cerebrospinal fluid (CSF). Our group identified a major tau cleavage at amino acid (aa) 224 in CSF

Dronedarone treatment following cardioversion in patients with atrial fibrillation/flutter : A post hoc analysis of the EURIDIS and ADONIS trials

Introduction: The phase 3 EURIDIS and ADONIS studies evaluated dronedarone for atrial fibrillation (AF)/atrial flutter (AFL) recurrence in patients with nonpermanent AF. Here we assessed whether patient characteristics and/or treatment outcomes in these studies differed based on the need for cardioversion before randomization. Methods: Time to adjudicated first AF/AFL recurrence, symptomatic recur

Studies of gas-particle interaction : Implications for the streaming instability in protoplanetary disks

We present the early results from a novel experiment to study a particle-laden flow, under a parameter regime relevant to the conditions in planet-forming systems. We investigate the gas-particle interactions to identify the presence of and details regarding the streaming instability, which is theoretically predicted to aid the coalescence of small dust grains to form planetesimals - the macroscop

Expression of the CGRP Family of Neuropeptides and their Receptors in the Trigeminal Ganglion

The calcitonin gene-related peptide (CGRP) family of neuropeptides, consists of CGRP, adrenomedullin, amylin, and calcitonin. The receptors consist of either calcitonin receptor-like receptor (CLR) or calcitonin receptor (CTR) which for function needs an accessory protein, receptor activity-modifying proteins (RAMPs). CGRP has a pivotal role in primary headaches but the role of the other members o

Fermentation of Cauliflower and White Beans with Lactobacillus plantarum – Impact on Levels of Riboflavin, Folate, Vitamin B12, and Amino Acid Composition

As diets change in response to ethical, environmental, and health concerns surrounding meat consumption, fermentation has potential to improve the taste and nutritional qualities of plant-based foods. In this study, cauliflower, white beans, and a 50:50 cauliflower-white bean mixture were fermented using different strains of Lactobacillus plantarum. In all treatments containing cauliflower, the pH

Multimeric fusion single-chain variable fragments as potential novel high-capacity ligands

In basic and applied biotechnology, design of affinity ligands has become essential for high-capacity applications such as affinity-based downstream processes for therapeutic molecules. Here, we established a proof-of-concept for the use of multimeric fusion single-chain variable fragment (scFvs) as high-capacity ligands in affinity adsorbents. Mono- and di/tri-scFvs separated by Pro-rich negative

The properties of α-synuclein secondary nuclei are dominated by the solution conditions rather than the seed fibril strain

Amyloid fibrils of α-synuclein (α-syn) are a component of Lewy bodies, the characteristic hallmark of Parkinson's disease. Amyloid fibrils arise through primary nucleation from monomers, which in the case of α-syn is often heterogeneous, followed by the growth of the nuclei by monomer addition. Secondary nucleation corresponds to the formation of new fibrils facilitated by pre-existing fibrils. Wh

Pelvic sentinel lymph node biopsy in endometrial cancer- A simplified algorithm based on histology and lymphatic anatomy

Objective: To achieve the full potential of sentinel lymph node (SLN) detection in endometrial cancer, both presumed low- A nd high-risk groups should be included. Perioperative resource use and complications should be minimized. Knowledge on distribution and common anatomical sites for metastatic SLNs may contribute to optimizing the concept while maintaining sensitivity. Proceeding from previous

Investment shocks and inequality dynamics

We explore the dynamics of income and income inequality under asymmetric information in credit markets. Within a stochastic overlapping-generations framework, we study the investment decision of entrepreneurs with heterogeneous abilities. Under information asymmetry, banks do not observe entrepreneurial ability and offer a single pooled loan contract to all entrepreneurs. We show that, following a