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Alpha-Synuclein Cell-to-Cell Transfer and Seeding in Grafted Dopaminergic Neurons In Vivo.

Several people with Parkinson's disease have been treated with intrastriatal grafts of fetal dopaminergic neurons. Following autopsy, 10-22 years after surgery, some of the grafted neurons contained Lewy bodies similar to those observed in the host brain. Numerous studies have attempted to explain these findings in cell and animal models. In cell culture, α-synuclein has been found to transfer fro

Orientalist Social Work: Cultural otherization of Muslim Immigrants in Sweden

This aim of this article is to critically examine how the concept of culture is used in Sweden to explain the “failure” or the difficulties that Muslim immigrant families are experiencing with regards to their integration into the dominant society. Whereas, the Swedish society is often represented as ‘modern’, ‘progressive’, and ‘democratic’, immigrants with Muslim backgrounds are predominately de

Post cardiac arrest care and follow-up in Sweden - a national web-survey.

Recent decades have shown major improvements in survival rates after cardiac arrest. However, few interventions have been tested in order to improve the care for survivors and their family members. In many countries, including Sweden, national guidelines for post cardiac arrest care and follow-up programs are not available and current practice has not previously been investigated. The aim of this

Lacosamide as treatment of epileptic seizures - cost utility results for Sweden.

Bolin K, Berggren F, Forsgren L. Lacosamide as treatment of epileptic seizures - cost utility results for Sweden. Acta Neurol Scand: DOI: 10.1111/j.1600-0404.2009.01320.x. (c) 2010 The Authors Journal compilation (c) 2010 Blackwell Munksgaard. Objectives - To calculate cost per additional quality-adjusted life-year (QALY) for lacosamide as adjunctive treatment for patients with uncontrolled partia

CGRP blockers in migraine therapy: where do they act?

Calcitonin gene-related peptide (CGRP) is expressed throughout the CNS and peripheral nervous system, consistent with control of vasodilatation, nociception, motor function, secretion and olfaction. alphaCGRP is prominently localized in primary afferent C and Adelta fibres of spinal and trigeminal ganglia. Activation of the trigeminal nerve results in antidromic release of CGRP, acting through a C

Fogar i våtrum

Kostnaderna för att åtgärda fukt- och vattenskador i våra våtrum har ökat dramatiskt och oroväckande under senare år. I den skadeinventering som ingick i SABOs stora projekt 'Fukt och mögel i flerbostadshus' uppvisade 11,3 procent av våtrummen skador av olika slag