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Case-control studies on risk factors for myeloid leukemias and myelodysplastic syndromes

Popular Abstract in Swedish Denna avhandling består av en tillämpad och en teoretisk del. I den tillämpade delen studeras tänkbara riskfaktorer för blodsjukdomarna myeloisk leukemi (ML) och myelodysplastiska syndrom (MDS). Den teoretiska delen tar upp några metodproblem som kan uppstå i epidemiologiska undersökningar som utnyttjar databaser innehållande uppgifter om andelen personer i olika yrkesgCase-control studies comprising telephone interviews for 333 cases of acute myeloid leukemia (AML), 226 cases of Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML), 330 cases of myelodysplastic syndromes (MDS), and matched controls were conducted. Information had to be obtained from next-of-kin much more often for cases (85%) than for controls (18%). Tobacco smoking was associated

CFD Investigation of Heat Transfer in a Diesel Engine with Diesel and PPC Combustion Modes

In this study, an investigation was made on a heavy duty diesel engine using both conventional diesel combustion mode and a partially premixed combustion (PPC) mode. A segment mesh was built up and modeled using the commercial CFD code AVL FIRE, where only the closed volume cycle, between IVC and EVO, was modeled. Both combustion modes were validated using experimental data, before a number of hea

Äldre personers rätt till omvårdnad - Behov, kompetenser, myter och evidens

År 2030 beräknas var fjärde person i Sverige vara 65 år eller äldre. Detta ställer stora krav på kunskapen om åldrandet och åldrandets sjukdomar och omvårdnad av äldre personer – i synnerhet när det gäller de allra äldsta. Äldre personer som bor på särskilda boenden är ofta multisjuka eller har nedsatt beslutsförmåga, i huvudsak till följd av demenssjukdom. De finns i dag goda kunskapsunderlag so

Doppler Velocimetry in the Evaluation of Fetal Well-Being

Ultrasound Doppler velocimetry was used to predict fetal well-being. The uterine artery blood velocimetry seemed to be a good predictor of perinatal outcome in high-risk pregnancies and a complement to umbilical artery velocimetry. The fetal middle cerebral artery blood velocimetry might be an early sign of fetal hypoxia. In pregnancies with decreased perception of fetal movements, the non stress

Evolution of hordein gene organization in three Hordeum species.

The inheritance pattern of hordein, the seed storage protein in barley, has been studied in two wild Hordeum species, H. murinum and H. pusillum. Three different diploid populations of each species were crossed, and the F1 plants were self-pollinated. The seeds with an F2 genotype were studied by sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE). Several differences could be ob

Male and female selective mechanisms, reproductive success and gene flow

In this thesis, I have studied male and female selective mechanisms that can affect plant reproductive success and gene flow. I have focussed on sexually selected traits, mainly pollen competition and maternal sorting mechanisms, for example through non-random ovule abortion. The main question was; what kind of traits can influence the most successful pollen donor or maternal sorting process? I fo

Optimisation and Application of Intense High-Order Harmonic Pulses

The high-order harmonics that are created in the interaction between an intense laser pulse (around 1014 W/cm2) and a gas medium are studied. The high-order harmonic radiation is a relatively new source of coherent radiation in the short wavelength range. The high-order harmonics are interesting for applications because of their good spatial and temporal coherence, their short pulse duration and t