BACKGROUND: Soluble urokinase plasminogen activator receptor (suPAR) is a highly sensitive marker that reflects increased inflammation and is positively correlated with pro-inflammatory biomarkers. The aim of this study was to explore the relationship between suPAR, cardiovascular disease (CVD) risk factors and incidence of CVD. METHODS: suPAR was assessed in a random sample of participants (N=569

Both organizations and management theory seem obsessed with creativity and 'the new,' but lately, the 'newness' of this so-called 'new' has also been questioned. With this paper, I continue in this critical fashion and point to the peculiar fact that the obsession with the new is accompanied by just as strong a rejection of that which is different. Overcoming this paradox, the paper emphasizes the

Objective: To compare outcomes for women undergoing two in vitro fertilization (IVF) pregnancies with singletons and women undergoing one IVF twin pregnancy. The concept of single-embryo transfer in IVF has reduced the risks of both maternal and neonatal complications, but there is still a discussion of whether or not twins are a desired outcome of IVF. Design: Registry study. Setting: Not applica

Background: Prostate cancer patients have an increased risk of fractures as a consequence of skeletal metastases and osteoporosis induced by endocrine treatment. Data on incidence of fractures and risks in subgroups of men with prostate cancer are sparse. Our aim with this study is to report the risk of fractures among men with prostate cancer in a nationwide population-based study. Patients and m

Assessment of prognosis after out-of-hospital cardiac arrest (OHCA) is challenging. Cerebral computed tomography (cCT) scans are widely available, but the use in prognostication of comatose OHCA-patients is unclear. We evaluated the prognostic value of cCT in a clinical cohort of OHCA-patients.

Synapsins are a family of phosphoproteins that modulate the release of neurotransmitters from synaptic vesicles. The release of insulin from pancreatic beta-cells has also been suggested to be regulated by synapsins. In this study, we have utilized a knock out mouse model with general disruptions of the synapsin I and II genes [synapsin double knockout (DKO)]. Stimulation with 20 mM glucose increa

Patterns of nonsuicidal self-injury (NSSI) and their association with other psychological difficulties were studied in a community sample of young Swedish adolescents, by a 2-wave longitudinal design with a 1-year interval. Hierarchical cluster analysis at T1 identified eight NSSI subgroups in each gender, of which five were clearly replicated at T2. Among these were a subgroup with generalized hi

Introduction: Meniscal extrusion is thought to be associated with less meniscus coverage of the tibial surface, but the association of radiographic disease stage with quantitative measures of tibial plateau coverage is unknown. We therefore compared quantitative and semi-quantitative measures of meniscus position and morphology in individuals with bilateral painful knees discordant on medial joint

A desire for higher speed and performance in molecular profiling analysis at a reduced cost is driving a trend in miniaturization and simplification of procedures. Here we report the use of a surface acoustic wave (SAW) atomizer for fast sample handling in matrix-assisted laser desorption ionization mass spectrometry (MALDI MS) peptide and protein profiling of Islets of Langerhans, for future type

The diverse cichlid species flocks of the East African lakes provide a classical example of adaptive radiation. Territorial aggression is thought to influence the evolution of phenotypic diversity in this system. Most vertebrates mount hormonal (androgen, glucocorticoid) responses to a territorial challenge. These hormones, in turn, influence behavior and multiple aspects of physiology and morphol

Using data on the entire population in combination with data on almost all individuals in Sweden listed as inventors, we study how the probability of being listed on a patent as inventor is influenced by the density of other future inventors residing in the same region. In this process, we control for demographic and sector effects along with the educational characteristics of parents. This approa

The ignition process, mode of combustion and reaction front propagation in a partially premixed combustion (PPC) engine running with a primary reference fuel (87 vol% iso-octane, 13 vol% n-heptane) were investigated numerically in a large eddy simulation (LES). A one-equation sub-grid scale model coupled to the partially stirred reactor model and a finite rate chemical model were used in LES. Diff

The article deals with the genre consolidated government accounts of state-owned enterprises in Finland and Sweden. More specifically, the study is focused on the subgenre the foreword of the responsible minister, which we label Statement from the Minister in analogy with Statement from the CEO in the related genre corporate annual reports. The primary data consist of Statement from the Minister iThe article deals with the genre consolidated government accounts of state-owned enter-prises in Finland and Sweden. More specifically, the study is focused on the subgenre the foreword of the responsible minister, which we label Statement from the Minister in anal-ogy with Statement from the CEO in the related genre corporate annual reports. The pri-mary data consist of Statement from the Ministe

A precise U–Pb baddeleyite age (2251 ± 4 Ma) has been obtained for an ENE-trending dyke exposed near the Chhura region of the Bastar craton, and additional dykes of similar trend are also reported from other parts of the northern Bastar craton such as in the Dongergarh and Pakhanjore areas. We propose a new widespread ENE-trending ca. 2.25 Ga Chhura mafic dyke swarm in the Bastar craton, which rep

Western South Africa between Cape Town and the Namibian border hosts many dyke swarms that strike broadly to the NW and NNW, towards the reconstructed plume-centre of the c. 130 Ma Parana-Etendeka Large Igneous Province (LIP) but are undated. U-Pb ID-TIMS age determinations on baddeleyite from two NNW-striking dykes (~100 km long) parallel to the Namaqualand coast yield 487 ± 8 Ma and 482 ± 7 Ma a