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Proton magnetic resonance spectroscopy in brain tumours: clinical applications

Parallel to the rapid development of clinical MRI, MR spectroscopy (MRS) has, after starting as an analytical tool used in chemistry and physics, evolved to a noninvasive clinical examination. Most common neuroradiological diagnostic indications for MRS are functional inborn errors, neonatal hypoxia, ischaemia, metabolic diseases, white matter and degenerative diseases, epilepsy, inflammation, inf

Surveillance of Vaccine Safety: Comparison of parental reports with routine surveillance and a clinical trial

One way to maintain confidence in vaccination programmes is to improve monitoring of immunisation safety. We studied active parental reporting of adverse events after a booster dose of diphtheria-tetanus toxoid (DT). 7193 children received the vaccine. Questionnaires were submitted by 84.2% of the parents, who reported reactions for 9.2% of the children. Four percent of events were classified as m

Prediction of Parasitic Components in an Automotive Environment

The amount of electrical loads and the complexity of the electric system in a vehicle is increasing at the same time as the allowed development time is decreasing. Possibilities to predict the electromagnetic behaviour is therefore of great importance. This paper addresses the problems of low frequency electromagnetic crosstalk between cables in a harness. Analytical expressions for estimation of

Mechanisms of Transgene Silencing in Neural Cells -Implications for Ex Vivo Gene Therapy to the Brain

Popular Abstract in Swedish Ett nytt och experimentellt sätt att bota eller lindra sjukdomssymptom är att, istället för att tillföra en medicin, rätta till felet på en genetisk nivå. Detta kan åstadkommas genom att överföra nya, fungerande gener, sk transgener, till celler som då börjar producera protein, som i sin tur kan ge upphov till en terapeutisk effekt. I hjärnan skulle denna typ av behandlThe use of genetically modifi ed neural stem and progenitor cells could possibly be a future strategy for repairing a brain suffering from neurodegeneration. However, so far it has proven diffi cult to maintain sufficient levels of a transferred gene in suitable cell types, after transplantation. In the present thesis I studied the silencing of transgenes induced upon differentiation of neural pro

Declarative-knowledge-based reconfiguration of automation systems using a blackboard architecture

This article describes results of the work on knowledge representation techniques chosen for use in the European project SIARAS (Skill-Based Inspection and Assembly for Reconfigurable Automation Systems). Its goal was to create intelligent support system for reconfiguration and adaptation of robot-based manufacturing cells. Declarative knowledge is represented first of all in an ontology expressed

Aspects on ADM1 Implementation within the BSM2 Framework

The current work of developing a control simulation benchmark goes back to the work carried out within the COST Action 682 (“Integrated Wastewater Management”) and the IAWQ Task Group on Respirometry-Based control of the Activated Sludge Process in the late 90s. The work was continued in COST Action 624 until 2003 (Copp 2002). In 2005, the IWA Task Group on Benchmarking of Control Strategies for W

Stakeholders, Roles, Workflows and Requirements

Decisions makers in cities and urban areas continuously have to make important decisions to react or proactively identify new challenges, problems and conflicts. But as cities and urban areas have become more complex, well‐founded decisions have also become more difficult to make. Decisions cannot be purely based on intuitions but require a basis for assessments, which put great constraints on dec

Distribution, phenology and condition of Aquatic Warblers Acrocephalus paludicola migrating through Portugal.

We show that the low number of aquatic warblers Acrocephalus paludicola ringed in Portugal is explained by the low ringing effort, and that Portugal is an important country for its migration. Most of the seven sites where the species was detected are recognized for their biological importance and protected. There seemed to be a decline in the number of birds caught, particularly of juveniles, whic