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Copper-free huisgen 1,3-dipolar cycloaddition to 3-benzotriazolo-3-deoxy-β-D-galactopyranoside : Cyclization of a galactopyranoside azide and benzyne

Methyl 2-O-acetyl-3-benzotriazolo-4,6-O-benzylidene-3-deoxy- β -D-galactopyranoside was assembled by reacting benzyne, from 2-trimethylsilyl-trifluoromethansulfonylbenzene, and a secondary galactopyranoside azide in a copper-free Huisgen 1,3-dipolar cycloaddition. Following deprotection, the resulting benzotriazoles were evaluated as galectin inhibitors resulting in a 2-4 fold increase in affinity

Comparison of four neuropathological scales for Alzheimer's disease.

Objective: There are several neuropathological scales for staging of Alzheimer pathology. The system proposed by Braak and Braak is based on the topographic distribution of neurofibrillary tangles and neuropil threads, while that of the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) is based on the quantity of neocortical neuritic plaques. A combination of the Braak and CERAD s

Essays on Mechanism Design

This thesis makes a contribution to mechanism design: a field of economic theory concerned with constructing and analyzing economic mechanisms. Examples include design of auctions, voting systems, school choice, kidney exchange and many more. The thesis consists of four separate papers. Paper one and two proposes and analyzes two new iterative auction mechanisms for selling multiple heterogeneous

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Romanesque round church towers - a Skandinavian perspective: The aim of the article is to discuss the interpretation of the Romanesque round church towers seen from a Scandinavian perspective. After a research history and a geographical outlook, which passes Ireland, England and Holstein, the article focusses on the 15-19 churches with round towers in medieaval Denmark, Sweden and Norway, with th

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Denna biografiska artikel betonar att Olaus Petri fick avgörande betydelse för den tidiga, evangeliska reformationen i Sverige som predikant, psalmdiktare och som översättare i bibelhumanistisk anda, men att det är omstritt i vilken utsträckning han var beroende av Luther (inflytanden från Bucer). Olaus förkortade översättning av Luthers sommarpostilla hade en opolemisk tendens. Hans kyrkohandbok