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Status epilepticus (SE) leads to neurodegeneration as well as neurogenesis in the adult rat hippocampus. This thesis demonstrates that even if the neurogenic response initially is very pronounced, with a several-fold increase in cell proliferation, the survival of the newly formed neurons is compromised by a death mechanism involving mitochondria-related caspases. This conclusion is based on immun
Popular Abstract in Swedish Parksinson’s sjukdom (PD) är en neurodegenerativ sjukdom där dopamininnehållande (dopaminerga) nervceller gradvis dör av oklar anledning, vilket leder till störningar I rörelsemönstret hos patienten. Det finns för närvarande inte någon bot mot sjukdomen och de goda effekterna av medicinering avtar efter 5-10 år. Genom att transplantera nya dopaminerga nervceller från hTransplantation of embryonic dopaminergic neurones can ameliorate symptoms in Parkinson’s disease, but a major obstacle for clinical transplantations to overcome is the low survival (typically 5-10%) of implanted nigral neurones. If cell death in nigral grafts can be prevented, less embryonic tissue would be needed per transplantation session and hence more patients could receive intracerebral gra
Ett mätinstrument för registrering av trafikkonflikter i fordon via ”Jerk” har tagits fram. Metoden bygger på sambandet mellan ”Jerk” (en plötslig förändring i retardationen) och trafikkonflikt. Utrustningen består av en accelerometer, en liten videokamera, GPS samt datalogg för registrering av händelser (bildsekvens och kördata som föregick en säkerhetskritisk händelse). Resultaten från testkörni
Essä om Statens Biografbyrås historia och nerläggning 2011
Det finns goda skäl till att engagera studenterna i kamratbedömning vid både formativ och summativ examination. Vi har under kursen Molekylär Cellbiologi för Ekosystemvetare vid LTH undersökt studenternas förmåga att bedöma muntliga projektredovisningar och jämfört den med lärarnas. Under kursen genomförde studenterna ett litteraturprojekt där en muntlig gruppredovisning med efterföljande kamratdi
Practically all modern control systems are based upon microprocessors and complex microcontrollers that yield high performance and functionality. This volume focuses on the design of computer-controlled systems, featuring computational tools that can be applied directly and are explained with simple paper-and-pencil calculations. The use of computational tools is balanced by a strong emphasis on c
In present work, we describe the formation and deposition of mixed Langmuir monolayers composed of inert amphiphile molecular matrix and guest ligand-stabilized metal-core nanoclusters. Such approach allowed obtaining the ordered stable reproducible planar monolayer and multilayer nanocluster nanostructures on solid substrates. The use of novel polymeric Langmuir monolayers formed by amphiphilic p
Environmental assessment of buildings has become an increasing research field and the methodology of LCA is increasingly used. In case studies, the phase after demolition is mostly either excluded or handled in a rather limited way. However, in the design phase, the aspects of future recycling needs to be regarded and by that the phases after demolition. Inclusion of these aspects in the assessmen
Popular Abstract in Swedish Vi tror på chefer och vi tror på lärande. Inte minst tror vi på chefers lärande. Den dominerande föreställningen är dessutom att chefer, via reflekterade erfarenheter, utvecklar en allt mer sofistikerad förståelse för sitt arbete, som i sin tur ligger till grund för ett skickligt agerande. Metaforiskt uttryckt kan läranderiktningen beskrivas som en resa från dum till klWe believe in managers and we believe in learning. Not least, we believe in managerial learning. Further, the dominant conception is that managers, through reflection on experience, develop an increasingly sophisticated understanding of their work, which in turn renders increasingly skillful managerial actions. Metaphorically, this learning trajectory can be described as a journey from stupidity t
The MUI framework supports composition of ad-hoc applications from services available on ad-hoc networked devices. MUI is an open-ended framework, relying on migrating user interfaces and standardized data formats for connecting services, allowing existing devices to be connected to new devices without needing any pre-defined knowledge of their services. We illustrate the benefits of the approach
Popular Abstract in Swedish Förmågan att kunna hitta mat är väldigt viktigt för alla djur eftersom detta påverkar flera saker, t ex hur snabbt man växer. Det i sin tur påverkar vilken roll man har i en grupp, hur mycket energi man har råd att lägga på fortplantning och hur många ungar man får. Att söka mat är oftast för-knippat med att äta, men inkluderar även andra aspekter som att söka efter matThe foraging ability of an organism is essential since it affects various traits, e.g. growth, reproduction effort, social status and, ultimately, fitness. Foraging is often associated with food intake but includes more aspects such as searching for and assessing food patches and evaluating the patch as good or bad compared to the rest of the environment. On top of that, a forager also has to surv
Key Messages • Sweden has an ideal opportunity to become a more important effect, reflecting the views of several Swedish organisations active international partner in DRR and resilience activities, originating in this area. from its strong history of donor support and long engagement • Acting on this opportunity would enable timely Swedish in DRR. contributions to the increasing global debate o
On 28 May 2009, at a closed meeting in Brussels, ministers and state secretaries of education and science from several EU countries decided to build the European Spallation Source (ESS) in Lund, Sweden. Or did they? It is common for big European science projects to be surrounded by secrecy and political deceit, but the ESS is extraordinary in its elusiveness. There is a remarkable lack of concrete
New high-efficiency power cycles and environmentally friendly cycles have introduced combustion atmospheres that differ from the traditional hydrocarbon-air mixtures. Wet cycles, solid oxide fuel cell with a gas turbine (SOFC-GT), CO2 separation/capture and biogas combustion are processes that involve high concentrations of inert gases such as H 2O, CO2 and N2
Popular Abstract in English Vernacular (local) architecture is in danger and about to disappear in several parts of the world. What we call native, traditional and handmade will disappear gradually and then the true meaning of vernacular vanishes. The present thesis shows that the disappearance of vernacular traditional skills creates an increasing threat to the existence of desert vernacular archDesert vernacular architecture has always been the product of a sustainable building cycle. People inherited the traditional way of building from their ancestors and the knowledge was transferred and developed from one generation to another. Inhabitants responded to their environment and climate through trial and error in a way that satisfied their needs and aspirations to create a developing buil
The rainflow filter is a non-linear filter which can be used to eliminate small-amplitude oscillations in a signal. In this paper, two approaches for investigation of the filter by means of an approximating transfer function are presented. The estimates are obtained from rainflow-filtered spectral simulations. One method is based on clipped Gaussian processes, the other uses a spline interpolation
