Haemorrhages represent a major complication of treatment with vitamin K antagonists. In cases of severe bleeding, a prompt effect on the increased International Normalized Ratio value is vital to achieve haemostasis. As conventional treatment, that is plasma or plasma-derived concentrates, carries the risk of blood-borne virus transmission, new treatments are needed. An open, multicentre pilot tri

Despite its recognition as an important source of variation in recruitment probability, the ecological processes leading to mortality between fledging and independence are poorly studied. Accordingly, the proximate and ultimate impact of bottom-up (food limitation) and top-down factors (predators, pathogens) for individual survival as well as population productivity is largely unknown in most terr

Intrastriatal transplants of embryonic ventral mesencephalon can cause dyskinesia in patients with Parkinson's disease (PD). We assessed the impact of transplant size on the development of graft-induced dyskinesia. Rats with unilateral 6-hydroxydopamine lesions were primed to exhibit l-DOPA-induced dyskinesia. They were then intrastriatally grafted with different quantities of embryonic ventral me

Asymmetrical flow field-flow fractionation (AsFIFFF) in combination with multi-angle light scattering (MALS) was applied to cationic potato amylopectin (CPAP) to investigate how molar mass, root-mean-square (r.m.s.) radius and shape was influenced by different conditions of jet-cooking. The effect of different jet-cooking temperatures in the range 110 degrees C - 140 degrees C was studied in an ex

Patients who continue to stiffer from lasting and severely disabling angina pectoris despite Optimum drug treatment and who are not suitable candidates for invasive procedures,. suffer from a condition referred to as "chronic refractory angina pectoris". Based on the available data, spinal cord Stimulation, SCS, is considered Lis the first-fine additional treatment for these patients by the Europe

For a detailed understanding of the function of photosystem II (PSII), a molecular structure is needed, The crystal structure has not yet been determined, but the PSII reaction center proteins D1 and D2 show homology with the L and M subunits of the photosynthetic reaction center from purple bacteria, We have modeled important parts of the D1 and D2 proteins on the basis of the crystallographic st

Rationale: Budesonide/formoterol and tiotropium are commonly used maintenance treatments for patients with chronic obstructive pulmonary disease. Combining these medications may provide additional benefits. Objectives: To assess the efficacy and tolerability of budesonide/formoterol added to tiotropium in patients eligible for inhaled corticosteroid/long-acting beta(2)-agonist combination therapy.

The strength of the Zeeman splitting induced by an applied magnetic field is an important factor for the realization of spin-resolved transport in mesoscopic devices. We measure the Zeeman splitting for a quantum point contact etched into a Ga0.25In0.75As quantum well, with the field oriented parallel to the transport direction. We observe an enhancement of the Lande g-factor from vertical bar g*v

Complex traits, including inflammatory rheumatic diseases, have important genetic features, but most of the responsible genes have not been conclusively identified. Genetic analysis of inbred animal models and comparative genetics - the comparison of genes between different species - might help to identify the crucial genes and to investigate more directly the biology involved. Genome-wide linkage

Enzymatic hydrolysis of carboxymethyl cellulose (CMC) has been studied with purified endoglucanases Hi Cel5A (EG II), Hi Cel7B (EG I), and Hi Cel45A (EG V) from Humicola insolens, and Tr Cel7B (EG I), Tr Cel12A (EG III), and Tr Cel45Acore (EG V) from Trichoderma reesei. The CMC, with a degree of substitution (DS) of 0.7, was hydrolyzed with a single enzyme until no further hydrolysis was observed.

To assess the level of posttraumatic stress disorder (PTSD) symptoms among Bosnian war refugees, a consecutive cohort of 206 Bosnian refugees, arriving in Sweden in 1993, was screened for PTSD using a modified version of the self-report instrument PTSS-10. A comparison group of 387 visitors to seven Swedish health centers was recruited. Prevalence of possible PTSD, using two estimates, was 18 to 3

A new species of Delia Robineau-Desvoidy is described from Europe ( Denmark, Sweden, Finland and Czech Republic) by the name of D. coarctoides. It is very similar to and has been confused with the wheat bulb fly, D. coarctata (Fallen), a well known anthomyiid pest species of cereals and grasses in Europe. A brief overview of the D. coarctata species group and a key to males and females are given.

An experimental investigation of heat transfer and fluid flow in a rectangular duct roughened by broken V-shaped ribs pointing upstream was carried out. The rectangular duct had art aspect ratio of 1/8, and the Reynolds number range was from 1000 to 6000. Liquid Crystal Thermography (LCT) was used to obtain the detailed heat transfer distributions on the ribbed wall. The main observed characterist

Lipid freezing in dilute sonicated vesicular dispersions was studied using differential scanning calorimetry (DSC) and H-1 NMR. For charged, anionic, or cationic lipids, approximately half of the lipids remain in a fluid state when cooled 20 degrees C below the main chain melting temperature. With a zwitterionic phospholipid, on the other hand, essentially no supercooling of the liquid state was o

In this study a homogeneous liquid-liquid extraction based on the Ph-dependent phase-separation process was investigated using a ternary solvent system (water-acetic acid-chloroform) for the preconcentration of Cu2+ ions. 8-Hydroxy quinoline was used as the chelating agent prior to its extraction. Flame atomic absorption spectro photometry using acetylene-air flame was used for the quantitation of